Search Results - "Kosar, Andrew"
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Novel, Rapid, and Inexpensive Cell-Based Quantification of Antimalarial Drug Efficacy
Published in Antimicrobial Agents and Chemotherapy (01-05-2004)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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The structure of malaria pigment β-haematin
Published in Nature (London) (16-03-2000)“…Despite the worldwide public health impact of malaria, neither the mechanism by which the Plasmodium parasite detoxifies and sequesters haem, nor the action of…”
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Drug resistance-associated pfCRT mutations confer decreased Plasmodium falciparum digestive vacuolar pH
Published in Molecular and biochemical parasitology (2004)“…Elucidating the altered physiology of various chloroquine resistant (CQR) strains of Plasmodium falciparum is essential for understanding the molecular basis…”
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Phase homogeneity and crystal morphology of the malaria pigment β-hematin
Published in Acta crystallographica. Section D, Biological crystallography. (01-10-2002)“…Hemoglobin digestion in the intraerythrocytic trophozoite stages of the malaria parasite releases large quantities of heme, which is then detoxified by…”
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Propionic acid side chain hydrogen bonding in the malaria pigment β-hematin
Published in Biochemical and biophysical research communications (31-05-2002)“…Malaria pigment, or β-hematin, the insoluble heme detoxification product resulting from the intraerythrocitic digestion of hemoglobin by young malaria…”
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Plasmodium falciparum strain GC-03 exhibits hyper-gametocytogenesis in partially hemoglobin depleted red blood cells
Published in Molecular and biochemical parasitology (01-02-2005)Get full text
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The reversible hydration of the malaria pigment β-hematin
Published in Canadian journal of chemistry (01-11-2003)“…β-Hematin, the crystalline heme detoxification product of red blood cell digestion by the malaria parasite, can reversibly absorb up to 14% of its mass in…”
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Structure of the Amodiaquine−FPIX μ Oxo Dimer Solution Complex at Atomic Resolution
Published in Inorganic chemistry (13-12-2004)“…Using NMR inversion recovery experiments and XPLOR distance restraint calculations, we recently deduced the structure of ferriprotoporphyrin IX (FPIX) heme μ…”
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The reversible hydration of the malaria pigment [beta]-hematin1
Published in Canadian journal of chemistry (01-11-2003)“…[beta]-Hematin, the crystalline heme detoxification product of red blood cell digestion by the malaria parasite, can reversibly absorb up to 14% of its mass in…”
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The structure and physical analysis of the malaria pigment, hemozoin
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Dissertation -
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The reversible hydration of the malaria pigment b-hematin
Published in Canadian journal of chemistry (01-11-2003)“…b-Hematin, the crystalline heme detoxification product of red blood cell digestion by the malaria parasite, can reversibly absorb up to 14% of its mass in…”
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Journal Article -
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The structure and physical analysis of the malaria pigment, hemozoin
Published 01-01-2002“…This dissertation is divided into four sections. Chapter 1 provides background information on the malaria problem and the research that has been conducted thus…”
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Dissertation