Search Results - "Kosaka, Mitsuko"
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Conclusive Evidence for OCT4 Transcription in Human Cancer Cell Lines: Possible Role of a Small OCT4‐Positive Cancer Cell Population
Published in Stem cells (Dayton, Ohio) (01-09-2018)“…The role of octamer‐binding transcription factor 4 (OCT4) in human cancer is still debated. Although many studies have been published on human OCT4,…”
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Prognostic value of OCT4A and SPP1C transcript variant co-expression in early-stage lung adenocarcinoma
Published in BMC cancer (05-06-2020)“…Octamer-binding transcription factor 4A (OCT4A) is essential for cell pluripotency and reprogramming both in humans and mice. To date, however, the function of…”
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Novel Variants of Oct-3/4 Gene Expressed in Mouse Somatic Cells
Published in The Journal of biological chemistry (07-11-2008)“…It has been suggested that Oct-3/4 may regulate self-renewal in somatic stem cells, as it does in embryonic stem cells. However, recent reports raise the…”
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Tsukushi functions as a Wnt signaling inhibitor by competing with Wnt2b for binding to transmembrane protein Frizzled4
Published in Proceedings of the National Academy of Sciences - PNAS (06-09-2011)“…The Wnt signaling pathway is essential for the development of diverse tissues during embryogenesis. Signal transduction is activated by the binding of Wnt…”
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Induction of photoreceptor-specific phenotypes in adult mammalian iris tissue
Published in Nature neuroscience (01-12-2001)“…We show that iris tissue in the adult rat eye, which is embryonically related to the neural retina, can generate cells expressing differentiated neuronal…”
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Developmental ability of cloned embryos from neural stem cells
Published in Reproduction (Cambridge, England) (01-12-2006)“…The success rate is generally higher when cloning mice from embryonic stem (ES) cell nuclei than from somatic cell nuclei, suggesting that the embryonic nature…”
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Molecular function of Tsukushi on neuronal stem cells
Published in Neuroscience research (2009)Get full text
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Abstract 5125: Biological and clinical value of OCT4A/SPP1C axis in endometrial and lung adenocarcinoma
Published in Cancer research (Chicago, Ill.) (15-06-2022)“…Background: It is largely unclear whether octamer-binding transcription factor 4A (OCT4A, OCT3/4A) functions physiologically or pathologically in adult somatic…”
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Multipotent cells from mammalian iris pigment epithelium
Published in Developmental biology (01-04-2007)“…The regeneration of lens tissue from the iris of newts has become a classical model of developmental plasticity, although little is known about the…”
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Novel Variants of Oct-3/4 Gene Expressed in Mouse Somatic CellsS
Published in The Journal of biological chemistry (07-11-2008)“…It has been suggested that Oct-3/4 may regulate self-renewal in somatic stem cells, as it does in embryonic stem cells. However, recent reports raise the…”
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Immediate differentiation of neuronal cells from stem/progenitor-like cells in the avian iris tissues
Published in Experimental eye research (01-06-2014)“…A simple culture method that was recently developed in our laboratory was applied to the chick iris tissues to characterize neural stem/progenitor-like cells…”
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Retinal stem/progenitor properties of iris pigment epithelial cells
Published in Developmental biology (2006)“…Neural stem cells/progenitors that give rise to neurons and glia have been identified in different regions of the brain, including the embryonic retina and…”
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Architecture of the subendothelial elastic fibers of small blood vessels and variations in vascular type and size
Published in Microscopy and microanalysis (01-04-2013)“…Most blood vessels contain elastin that provides the vessels with the resilience and flexibility necessary to control hemodynamics. Pathophysiological…”
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Adult human retinal pigment epithelial cells capable of differentiating into neurons
Published in Biochemical and biophysical research communications (26-03-2004)“…We investigated the ability of adult human RPE cells to differentiate into neurons. Two cell lines were evaluated. The cells were cultured in medium with 8%…”
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The Kinetics of Induction of Hox1.6 and C-JUN mRNA during Three Different Ways of Inducing Differentiation in Teratocarcinoma F9 Cells
Published in In vitro cellular & developmental biology. Animal (01-06-1995)“…Changes in Hox1.6 and c-jun gene expression were examined upon F9 cell differentiation that was induced by three independent methods: a drug treatment with…”
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Tsukushi inhibits the proliferation of retinal stem/progenitor cells
Published in Developmental biology (01-06-2007)Get full text
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WITHDRAWN: Tsukushi inhibits the proliferation of retinal stem/progenitor cells
Published in Developmental biology (01-04-2007)Get full text
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Tsukushi inhibits proliferation of retinal stem cells by Wnt signalling inhibition
Published in Neuroscience research (2007)Get full text
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In vitro culture system for iris-pigmented epithelial cells for molecular analysis of transdifferentiation
Published in Experimental cell research (15-12-1998)“…Dissociated cells of the iris-pigmented epithelium (IPE) from a 1-day-old chick grew in monolayer culture and stably maintained their differentiated state when…”
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Localization of FGFR-1 in axotomized and peripheral nerve transplanted ferret retina
Published in Neuroreport (16-12-1999)“…RETINAL ganglion cells (RGCs) survive axotomy and regenerate their axons into the peripheral nerve graft in adult mammals. To understand the potential role of…”
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