Search Results - "Kosai, Yuki"

Design, synthesis and biological evaluation of novel pyridine derivatives as gut-selective NaPi2b inhibitors by Ushiki, Yasunobu, Kawabe, Kenichi, Yamamoto-Okada, Kumiko, Uneuchi, Fumito, Asanuma, Yuta, Yamaguchi, Chitose, Ohta, Hiroshi, Shibata, Tsuyoshi, Abe, Tomohiro, Okumura-Kitajima, Lisa, Kosai, Yuki, Endo, Mayumi, Otake, Katsumasa, Munetomo, Eiji, Takahashi, Teisuke, Kakinuma, Hiroyuki

“…[Display omitted] We previously reported thiophene derivatives as gut-selective (minimally systemic) and potent sodium-dependent phosphate transport protein 2b…”
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Design, synthesis and biological evaluation of novel indole derivatives as gut-selective NaPi2b inhibitors by Ushiki, Yasunobu, Kawabe, Kenichi, Yamamoto-Okada, Kumiko, Uneuchi, Fumito, Asanuma, Yuta, Yamaguchi, Chitose, Ohta, Hiroshi, Shibata, Tsuyoshi, Abe, Tomohiro, Okumura-Kitajima, Lisa, Kosai, Yuki, Endo, Mayumi, Otake, Katsumasa, Munetomo, Eiji, Takahashi, Teisuke, Kakinuma, Hiroyuki

“…[Display omitted] Intestinal sodium-dependent phosphate transport protein 2b (SLC34A2, NaPi2b) inhibitors are expected to be potential new candidates for…”
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Design, synthesis and biological evaluation of novel 1H-pyrazole-4-carbonyl-4,5,6,7-tetrahydrobenzo [b]thiophene derivatives as gut-selective NaPi2b inhibitors by Ushiki, Yasunobu, Kawabe, Kenichi, Yamamoto-Okada, Kumiko, Uneuchi, Fumito, Asanuma, Yuta, Yamaguchi, Chitose, Ohta, Hiroshi, Shibata, Tsuyoshi, Abe, Tomohiro, Okumura-Kitajima, Lisa, Kosai, Yuki, Endo, Mayumi, Otake, Katsumasa, Munetomo, Eiji, Takahashi, Teisuke, Kakinuma, Hiroyuki

“…[Display omitted] Intestinal sodium-dependent phosphate transport protein 2b (SLC34A2, NaPi2b) inhibitors are expected to be potential new candidates for…”
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Expression, subunit composition, and function of AMPA-type glutamate receptors are changed in activated microglia; possible contribution of GluA2 (GluR-B)-deficiency under pathological conditions by Beppu, Kaoru, Kosai, Yuki, Kido, Mizuho A., Akimoto, Nozomi, Mori, Yuki, Kojima, Yuichiro, Fujita, Kyota, Okuno, Yuko, Yamakawa, Yukiko, Ifuku, Masataka, Shinagawa, Rika, Nabekura, Junichi, Sprengel, Rolf, Noda, Mami

“…Microglia express AMPA (α‐amino‐hydroxy‐5‐methyl‐isoxazole‐4‐propionate)‐type of glutamate (Glu) receptors (AMPAR), which are highly Ca2+ impermeable due to…”
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Neuroprotective role of bradykinin because of the attenuation of pro‐inflammatory cytokine release from activated microglia by Noda, Mami, Kariura, Yukihiro, Pannasch, Ulrike, Nishikawa, Kaori, Wang, Liping, Seike, Toshihiro, Ifuku, Masataka, Kosai, Yuki, Wang, Bing, Nolte, Christiane, Aoki, Shunsuke, Kettenmann, Helmut, Wada, Keiji

“…Bradykinin (BK) has been reported to be a mediator of brain damage in acute insults. Receptors for BK have been identified on microglia, the pathologic sensors…”
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A sensitive internal standard method for the determination of melatonin in mammals using precolumn oxidation reversed-phase high-performance liquid chromatography by HAMASE, Kenji, HIRANO, Junzo, KOSAI, Yuki, TOMITA, Tatsunosuke, ZAITSU, Kiyoshi

“…A sensitive and accurate internal standard method to determine melatonin in mammalian tissues and physiological fluids has been described. This method includes…”
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A sensitive internal standard method for the determination of melatonin in mammals using precolumn oxidation reversed-phase high-performance liquid chromatography by Hamase, Kenji, Hirano, Junzo, Kosai, Yuki, Tomita, Tatsunosuke, Zaitsu, Kiyoshi

“…A sensitive and accurate internal standard method to determine melatonin in mammalian tissues and physiological fluids has been described. This method includes…”
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Attenuation of cytokine release from microglia by bradykinin by Noda, Mami, Kariura, Yukihiro, Pannasch, Ulrike, Nishikawa, Kaori, Wang, Liping, Seike, Toshihiro, Ifuku, Masataka, Kosai, Yuki, Wang, Bing, Nolte, Christiane, Aoki, Shunsuke, Kettenmann, Helmut, Wada, Keiji

“…Bradykinin (BK) has been reported to be a mediator of brain damage in acute insults. Receptors for BK have been identified on microglia, the pathologic sensors…”
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