Search Results - "Kos, Z."

The evaluation of tumor-infiltrating lymphocytes (TILs) in breast cancer: recommendations by an International TILs Working Group 2014 by Salgado, R., Denkert, C., Demaria, S., Sirtaine, N., Klauschen, F., Pruneri, G., Wienert, S., Van den Eynden, G., Baehner, F.L., Penault-Llorca, F., Perez, E.A., Thompson, E.A., Symmans, W.F., Richardson, A.L., Brock, J., Criscitiello, C., Bailey, H., Ignatiadis, M., Floris, G., Sparano, J., Kos, Z., Nielsen, T., Rimm, D.L., Allison, K.H., Reis-Filho, J.S., Loibl, S., Sotiriou, C., Viale, G., Badve, S., Adams, S., Willard-Gallo, K., Loi, S.

“…Evidence is strengthening for the morphological evaluation of tumor infiltrating lymphocytes (TILs) in breast cancer. Herein, the concepts for TILs assessment…”
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Novel epigenetic determinants of type 2 diabetes in Mexican-American families by Kulkarni, Hemant, Kos, Mark Z, Neary, Jennifer, Dyer, Thomas D, Kent, Jr, Jack W, Göring, Harald H H, Cole, Shelley A, Comuzzie, Anthony G, Almasy, Laura, Mahaney, Michael C, Curran, Joanne E, Blangero, John, Carless, Melanie A

“…Although DNA methylation is now recognized as an important mediator of complex diseases, the extent to which the genetic basis of such diseases is accounted…”
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Nematodynamics and structures in junctions of cylindrical micropores by Kos, Ž., Ravnik, M., Žumer, S.

“…We explore equilibrium structures and flow-driven deformations of nematic liquid crystals confined to 3D junctions of cylindrical micropores with homeotropic…”
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A pilot investigation of differential hydroxymethylation levels in patient-derived neural stem cells implicates altered cortical development in bipolar disorder by Kumar, Ashish, Kos, Mark Z, Roybal, Donna, Carless, Melanie A

“…Bipolar disorder (BD) is a chronic mental illness characterized by recurrent episodes of mania and depression and associated with social and cognitive…”
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Blood-Based miRNA Biomarkers as Correlates of Brain-Based miRNA Expression by Kos, Mark Z, Puppala, Sobha, Cruz, Dianne, Neary, Jennifer L, Kumar, Ashish, Dalan, Emma, Li, Cun, Nathanielsz, Peter, Carless, Melanie A

“…The use of easily accessible peripheral samples, such as blood or saliva, to investigate neurological and neuropsychiatric disorders is well-established in…”
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The Cdc42/Rac1 regulator CdGAP is a novel E-cadherin transcriptional co-repressor with Zeb2 in breast cancer by He, Y, Northey, J J, Pelletier, A, Kos, Z, Meunier, L, Haibe-Kains, B, Mes-Masson, A-M, Côté, J-F, Siegel, P M, Lamarche-Vane, N

“…The loss of E-cadherin causes dysfunction of the cell–cell junction machinery, which is an initial step in epithelial-to-mesenchymal transition (EMT),…”
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Genz and Mendell-Elston Estimation of the High-Dimensional Multivariate Normal Distribution by Blondell, Lucy, Kos, Mark Z., Blangero, John, Göring, Harald H. H.

“…Statistical analysis of multinomial data in complex datasets often requires estimation of the multivariate normal (mvn) distribution for models in which the…”
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Whole Genome Sequence Data From Captive Baboons Implicate RBFOX1 in Epileptic Seizure Risk by Kos, Mark Z., Carless, Melanie A., Blondell, Lucy, Leland, M. Michelle, Knape, Koyle D., Göring, Harald H. H., Szabó, Charles Ákos

“…In this study, we investigate the genetic determinants that underlie epilepsy in a captive baboon pedigree and evaluate the potential suitability of this…”
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Genetic effects on DNA methylation and its potential relevance for obesity in Mexican Americans by Carless, Melanie A, Kulkarni, Hemant, Kos, Mark Z, Charlesworth, Jac, Peralta, Juan M, Göring, Harald H H, Curran, Joanne E, Almasy, Laura, Dyer, Thomas D, Comuzzie, Anthony G, Mahaney, Michael C, Blangero, John

“…Several studies have identified effects of genetic variation on DNA methylation patterns and associated heritability, with research primarily focused on…”
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Common biological networks underlie genetic risk for alcoholism in African‐ and European‐American populations by Kos, M. Z., Yan, J., Dick, D. M., Agrawal, A., Bucholz, K. K., Rice, J. P., Johnson, E. O., Schuckit, M., Kuperman, S., Kramer, J., Goate, A. M., Tischfield, J. A., Foroud, T., Nurnberger, J., Hesselbrock, V., Porjesz, B., Bierut, L. J., Edenberg, H. J., Almasy, L.

“…Alcohol dependence (AD) is a heritable substance addiction with adverse physical and psychological consequences, representing a major health and economic…”
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Data on genetic associations of carotid atherosclerosis markers in Mexican American and European American rheumatoid arthritis subjects by Arya, Rector, Escalante, Agustin, Farook, Vidya S., Restrepo, Jose F., Battafarano, Daniel F., Almeida, Marcio, Kos, Mark Z., Fourcaudot, Marcel J., Mummidi, Srinivas, Kumar, Satish, Curran, Joanne E., Jenkinson, Christopher P., Blangero, John, Duggirala, Ravindranath, del Rincon, Inmaculada

“…Carotid Intima-media thickness (CIMT) and plaque are well established markers of subclinical atherosclerosis and are widely used for identifying subclinical…”
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A genetic association study of carotid intima-media thickness (CIMT) and plaque in Mexican Americans and European Americans with rheumatoid arthritis by Arya, Rector, Escalante, Agustin, Farook, Vidya S., Restrepo, Jose F., Battafarano, Daniel F., Almeida, Marcio, Kos, Mark Z., Fourcaudot, Marcel J., Mummidi, Srinivas, Kumar, Satish, Curran, Joanne E., Jenkinson, Christopher P., Blangero, John, Duggirala, Ravindranath, del Rincon, Inmaculada

“…Little is known about specific genetic determinants of carotid-intima-media thickness (CIMT) and carotid plaque in subjects with rheumatoid arthritis (RA). We…”
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Genotype phasing in pedigrees using whole-genome sequence data by Blackburn, August N, Blondell, Lucy, Kos, Mark Z, Blackburn, Nicholas B, Peralta, Juan M, Stevens, Peter T, Lehman, Donna M, Blangero, John, Göring, Harald H H

“…Phasing is the process of inferring haplotypes from genotype data. Efficient algorithms and associated software for accurate phasing in pedigrees are needed,…”
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Exome Sequence Data From Multigenerational Families Implicate AMPA Receptor Trafficking in Neurocognitive Impairment and Schizophrenia Risk by Kos, Mark Z, Carless, Melanie A, Peralta, Juan, Blackburn, August, Almeida, Marcio, Roalf, David, Pogue-Geile, Michael F, Prasad, Konasale, Gur, Ruben C, Nimgaonkar, Vishwajit, Curran, Joanne E, Duggirala, Ravi, Glahn, David C, Blangero, John, Gur, Raquel E, Almasy, Laura

“…Schizophrenia is a mental disorder characterized by impairments in behavior, thought, and neurocognitive performance. We searched for susceptibility loci at a…”
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Exome sequences of multiplex, multigenerational families reveal schizophrenia risk loci with potential implications for neurocognitive performance by Kos, Mark Z., Carless, Melanie A., Peralta, Juan, Curran, Joanne E., Quillen, Ellen E., Almeida, Marcio, Blackburn, August, Blondell, Lucy, Roalf, David R., Pogue‐Geile, Michael F., Gur, Ruben C., Göring, Harald H.H., Nimgaonkar, Vishwajit L., Gur, Raquel E., Almasy, Laura

“…Schizophrenia is a serious mental illness, involving disruptions in thought and behavior, with a worldwide prevalence of about one percent. Although highly…”
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Using genetic information from candidate gene and genome-wide association studies in risk prediction for alcohol dependence by Yan, Jia, Aliev, Fazil, Webb, Bradley T., Kendler, Kenneth S., Williamson, Vernell S., Edenberg, Howard J., Agrawal, Arpana, Kos, Mark Z., Almasy, Laura, Nurnberger Jr, John I., Schuckit, Marc A., Kramer, John R., Rice, John P., Kuperman, Samuel, Goate, Alison M., Tischfield, Jay A., Porjesz, Bernice, Dick, Danielle M.

“…Family‐based and genome‐wide association studies (GWAS) of alcohol dependence (AD) have reported numerous associated variants. The clinical validity of these…”
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Dopamine perturbation of gene co-expression networks reveals differential response in schizophrenia for translational machinery by Kos, Mark Z., Duan, Jubao, Sanders, Alan R., Blondell, Lucy, Drigalenko, Eugene I., Carless, Melanie A., Gejman, Pablo V., Göring, Harald H. H.

“…The dopaminergic hypothesis of schizophrenia (SZ) postulates that positive symptoms of SZ, in particular psychosis, are due to disturbed neurotransmission via…”
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66P Digital profiling of immune biomarkers: Relation to anthracycline benefit by Shenasa, E., He, Y., Wang, Z., Tu, D., Gao, D., Kos, Z., Thornton, S., Nielsen, T.O.

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Novel QTL at chromosome 6p22 for alcohol consumption: Implications for the genetic liability of alcohol use disorders by Kos, Mark Z., Glahn, David C., Carless, Melanie A., Olvera, Rene, McKay, D. Reese, Quillen, Ellen E., Gelernter, Joel, Chen, Xiang-Ding, Deng, Hong-Wen, Kent, Jack W., Dyer, Thomas D., Göring, Harald H.H., Curran, Joanne E., Duggirala, Ravi, Blangero, John, Almasy, Laura

“…Linkage studies of alcoholism have implicated several chromosome regions, leading to the successful identification of susceptibility genes, including ADH4 and…”
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Selected rapporteur summaries from the XX world congress of psychiatric genetics, Hamburg, Germany, october 14-18, 2012 by Anderson-Schmidt, Heike, Beltcheva, Olga, Brandon, Mariko D., Byrne, Enda M., Diehl, Eric J., Duncan, Laramie, Gonzalez, Suzanne D., Hannon, Eilis, Kantojärvi, Katri, Karagiannidis, Iordanis, Kos, Mark Z., Kotyuk, Eszter, Laufer, Benjamin I., Mantha, Katarzyna, McGregor, Nathaniel W., Meier, Sandra, Nieratschker, Vanessa, Spiers, Helen, Squassina, Alessio, Thakur, Geeta A., Tiwari, Yash, Viswanath, Biju, Way, Michael J., Wong, Cybele C.P., O'Shea, Anne, DeLisi, Lynn E.

“…The XXth World Congress of Psychiatric Genetics (WCPG), sponsored by The International Society of Psychiatric Genetics (ISPG) took place in Hamburg, Germany on…”
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