Search Results - "Kos, CH"

Stem cell engraftment at the endosteal niche is specified by the calcium-sensing receptor by Scadden, David T, Adams, Gregor B, Chabner, Karissa T, Alley, Ian R, Olson, Douglas P, Szczepiorkowski, Zbigniew M, Poznansky, Mark C, Kos, Claudine H, Pollak, Martin R, Brown, Edward M

“…During mammalian ontogeny, haematopoietic stem cells (HSCs) translocate from the fetal liver to the bone marrow, where haematopoiesis occurs throughout…”
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Localization of a renal sodium-phosphate cotransporter gene to human chromosome 5q35 by Kos, C H, Tihy, F, Econs, M J, Murer, H, Lemieux, N, Tenenhouse, H S

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Cre/loxP system for generating tissue-specific knockout mouse models by KOS, Claudine H

“…Alteration of the mouse genome by conventional transgenic and gene-targeted approaches has greatly facilitated studies of gene function. However, a gene…”
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Marked Disturbance of Calcium Homeostasis in Mice With Targeted Disruption of the Trpv6 Calcium Channel Gene by Bianco, Suzy DC, Peng, Ji‐Bin, Takanaga, Hitomi, Suzuki, Yoshiro, Crescenzi, Alessandra, Kos, Claudine H, Zhuang, Liyan, Freeman, Michael R, Gouveia, Cecilia HA, Wu, Jiangping, Luo, Hongyu, Mauro, Theodora, Brown, Edward M, Hediger, Matthias A

“…We report the phenotype of mice with targeted disruption of the Trpv6 (Trpv6 KO) epithelial calcium channel. The mice exhibit disordered Ca2+ homeostasis,…”
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Mice deficient in alpha -actinin-4 have severe glomerular disease by Kos, CH, Le, T C, Sinha, S, Henderson, J M, Kim, SH, Sugimoto, H, Kalluri, R, Gerszten, R E, Pollak, M R

“…Dominantly inherited mutations in ACTN4, which encodes alpha -actinin-4, cause a form of human focal and segmental glomerulosclerosis (FSGS). By homologous…”
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The calcium-sensing receptor is required for normal calcium homeostasis independent of parathyroid hormone by Kos, CH, Karaplis, A C, Peng, Ji-Bin, Hediger, MA, Goltzman, D, Mohammad, K S, Guise, T A, Pollak, M R

“…The extracellular calcium-sensing receptor (CAR; alternate gene names, CaR or Casr) is a membrane-spanning G protein-coupled receptor. CaR is highly expressed…”
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Alpha-actinin-4-mediated FSGS: an inherited kidney disease caused by an aggregated and rapidly degraded cytoskeletal protein by Yao, June, Le, Tu Cam, Kos, Claudine H, Henderson, Joel M, Allen, Phillip G, Denker, Bradley M, Pollak, Martin R

“…Focal segmental glomerulosclerosis (FSGS) is a common pattern of renal injury, seen as both a primary disorder and as a consequence of underlying insults such…”
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Structure of Murine and Human Renal Type II Na+-Phosphate Cotransporter Genes (Npt2 and NPT2) by Hartmann, C. M., Hewson, A. S., Kos, C. H., Hilfiker, H., Soumounou, Y., Murer, H., Tenenhouse, H. S.

“…Na+-phosphate (Pi) cotransport across the renal brush border membrane is the rate limiting step in the overall reabsorption of filtered Pi. Murine and human…”
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Structure of murine and human renal type II Na super(+)-phosphate cotransporter genes (Npt2 and NPT2) by Hartmann, C M, Hewson, A S, Kos, CH, Hilfiker, H, Soumounou, Y, Murer, H, Tenenhouse, H S

“…Na super(+)-phosphate (Pi) cotransport across the renal brush border membrane is the rate limiting step in the overall reabsorption of filtered Pi. Murine and…”
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High resolution mapping of the renal sodium-phosphate cotransporter gene (NPT2) confirms its localization to human chromosome 5q35 by MCPHERSON, J. D, KRANE, M. C, WAGNER-MCPHERSON, C. B, KOS, C. H, TENENHOUSE, H. S

“…The precise chromosomal localization of the type II renal-specific Na+-phosphate (Pi) cotransporter (NPT2) gene (gene symbol SLC17A2) is necessary for the…”
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Comparative mapping of Na+-phosphate cotransporter genes, NPT1 and NPT2, in human and rabbit by Kos, C H, Tihy, F, Murer, H, Lemieux, N, Tenenhouse, H S

“…The chromosome locations of the rabbit (Oryctolagus cuniculus) Na+-phosphate cotransporter genes NPT1 and NPT2 were determined by fluorescence in situ…”
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