Search Results - "Korytowski, W"

Spontaneous Intermembrane Transfer of Various Cholesterol-Derived Hydroperoxide Species:  Kinetic Studies with Model Membranes and Cells by Vila, Andrew, Korytowski, Witold, Girotti, Albert W

“…Whereas spontaneous and protein-mediated transfer/exchange of cholesterol (Ch) between membranes has been widely studied, relatively little is known about the…”
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Antioxidant Action of Neuromelanin: The Mechanism of Inhibitory Effect on Lipid Peroxidation by Korytowski, W., Sarna, T., Zareba, M.

“…Iron and lipid peroxidation are believed to be involved in the degeneration of pigmented neurons in Parkinson′s disease. Melanin-iron interaction is thought to…”
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Bleaching of melanin pigments. Role of copper ions and hydrogen peroxide in autooxidation and photooxidation of synthetic dopa-melanin by Korytowski, W, Sarna, T

“…Bleaching of eumelanin has been studied in model systems consisting of synthetic dopa-melanin and various concentrations of hydrogen peroxide, molecular…”
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P-364 - Cholesterol hydroperoxide trafficking to macrophage mitochondria and its implications for atherogenesis under oxidative stress by Korytowski, W., Pabisz, P., Wawak, K., Girotti, AW

“…Under oxidative stress (chronic inflammation, obesity), scavenger receptor-expressing macrophages in arterial subendothelial space internalize oxidized LDL…”
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P-365 - Beneficial effects of inhibiting iNOS activity versus iNOS transcription in anti-tumor photodynamic therapy by Korytowski, W., Bazak, J., Fahey, J., Girotti, AW

“…We have shown that various cancer cells can exploit endogenous nitric oxide (NO) to resist elimination by photodynamic therapy (PDT) or cisplatin treatment…”
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Cholesterol hydroperoxide trafficking to macrophage mitochondria and its implications for atherogenesis under oxidative stress by Korytowski, W., Pabisz, P., Wawak, K., Girotti, AW

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Beneficial effects of inhibiting iNOS activity versus iNOS transcription in anti-tumor photodynamic therapy by Korytowski, W., Bazak, J., Fahey, J., Girotti, AW

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Photoinduced generation of hydrogen peroxide and hydroxyl radicals in melanins by Korytowski, W, Pilas, B, Sarna, T, Kalyanaraman, B

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Analysis of cholesterol and phospholipid hydroperoxides by high-performance liquid chromatography with mercury drop electrochemical detection by Korytowski, W, Bachowski, G J, Girotti, A W

“…High-performance liquid chromatography (HPLC) with reductive mode electrochemical detection on a mercury drop has been employed for the separation and…”
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Deleterious cholesterol hydroperoxide trafficking in star protein-expressing ma-10 leydig cells: Implications for oxidative stress-impaired steroidogenesis by Korytowski⁎, W., Girotti, A.W., Pilat, A., Schmitt, J.C.

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Reaction of superoxide anions with melanins: electron spin resonance and spin trapping studies by Korytowski, W, Kalyanaraman, B, Menon, I A, Sarna, T, Sealy, R C

“…Scavenging of superoxide radicals by melanin is a possible factor in the photoprotection afforded by melanin pigments. The reaction between superoxide anions…”
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Mechanism of dismutation of superoxide produced during autoxidation of melanin pigments by Korytowski, W, Hintz, P, Sealy, R C, Kalyanaraman, B

“…The hydrogen peroxide produced during the autoxidation of melanin pigments has been measured using an oxidase electrode. The autoxidation has been shown to…”
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Role of mitochondrial cardiolipin peroxidation in apoptotic photokilling of 5-aminolevulinate-treated tumor cells by Kriska, Tamas, Korytowski, Witold, Girotti, Albert W.

“…In 5-aminolevulinic acid (ALA)-based photodynamic therapy (PDT), ALA taken up by tumor cells is metabolized to protoporphyrin IX (PpIX), which sensitizes…”
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Loss of melanin from human RPE with aging: possible role of melanin photooxidation by Sarna, Tadeusz, Burke, Janice M., Korytowski, Witold, Różanowska, Małgorzata, Skumatz, Christine M.B., Zaręba, Agnieszka, Zaręba, Mariusz

“…The pigment melanin, which is believed to play a photoprotective role, was quantified here in human RPE cells from donors of different age. Electron spin…”
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Nitric oxide-induced resistance to lethal photooxidative damage in a breast tumor cell line by Niziolek, Magdalena, Korytowski, Witold, Girotti, Albert W.

“…The long-term effects of nitric oxide (NO) on cell susceptibility to photodynamic killing have been studied, using a human breast tumor line (COH-BR1)…”
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Cooperation of antioxidants in protection against photosensitized oxidation by Wrona, Marta, Korytowski, Witold, Różanowska, Małgorzata, Sarna, Tadeusz, Truscott, T.George

“…The aim of this study was to determine whether α-tocopherol and zeaxanthin offer synergistic protection against photosensitized lipid peroxidation mediated by…”
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Interactions of flavins with melanin. Studies on equilibrium binding of riboflavin to dopa-melanin and some spectroscopic characteristics of flavin-melanin complex by Kozik, A, Korytowski, W, Sarna, T, Bloom, A S

“…Natural melanins are photoprotective pigments that in mammals are principally found in the skin, hair, and eyes. Although the molecular mechanism of…”
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Photoreactivity of Aged Human RPE Melanosomes: A Comparison with Lipofuscin by Rozanowska, Malgorzata, Korytowski, Witold, Rozanowski, Bartosz, Skumatz, Christine, Boulton, Mike E, Burke, Janice M, Sarna, Tadeusz

“…To determine whether aging is accompanied by changes in aerobic photoreactivity of retinal pigment epithelial (RPE) melanosomes isolated from human donors of…”
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Reaction between ortho-semiquinones and oxygen: pulse radiolysis, electron spin resonance, and oxygen uptake studies by Kalyanaraman, B, Korytowski, W, Pilas, B, Sarna, T, Land, E J, Truscott, T G

“…The cytotoxicity to tumor cells or cardiotoxic side effects of certain para-quinone antitumor drugs have been attributed to the corresponding semiquinones and…”
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Evidence for the one-electron oxidation of 1-methyl-4-phenyl-2,3-dihydropyridinium (MPDP+) by Korytowski, W, Felix, C C, Kalyanaraman, B

“…Optical data have shown that the neurotoxin metabolite 1-methyl-4-phenyl-2,3-dihydropyridinium undergoes one-electron oxidation/reduction in the presence of…”
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