Search Results - "Kortum, Steve W"
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Design and Synthesis of a Pan-Janus Kinase Inhibitor Clinical Candidate (PF-06263276) Suitable for Inhaled and Topical Delivery for the Treatment of Inflammatory Diseases of the Lungs and Skin
Published in Journal of medicinal chemistry (26-01-2017)“…By use of a structure-based computational method for identification of structurally novel Janus kinase (JAK) inhibitors predicted to bind beyond the ATP…”
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Journal Article -
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Microfluidic-Enabled Intracellular Delivery of Membrane Impermeable Inhibitors to Study Target Engagement in Human Primary Cells
Published in ACS chemical biology (15-12-2017)“…Biochemical screening is a major source of lead generation for novel targets. However, during the process of small molecule lead optimization, compounds with…”
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Journal Article -
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Design and Synthesis of a Pan-Janus Kinase Inhibitor Clinical Candidate (PF-06263276) Suitable for Inhaled and Topical Delivery for the Treatment of Inflammatory Diseases of the Lungs and Skin
Published in Journal of medicinal chemistry (16-12-2016)“…By use of a structure-based computational method for identification of structurally novel Janus kinase (JAK) inhibitors predicted to bind beyond the ATP…”
Get full text
Journal Article