Search Results - "Kortright, Kaitlyn"

Phage Therapy: A Renewed Approach to Combat Antibiotic-Resistant Bacteria by Kortright, Kaitlyn E., Chan, Benjamin K., Koff, Jonathan L., Turner, Paul E.

“…Phage therapy, long overshadowed by chemical antibiotics, is garnering renewed interest in Western medicine. This stems from the rise in frequency of…”
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High-throughput discovery of phage receptors using transposon insertion sequencing of bacteria by Kortright, Kaitlyn E., Chan, Benjamin K., Turner, Paul E.

“…As the most abundant microbes on Earth, novel bacteriophages (phages; bacteria-specific viruses) are readily isolated from environmental samples. However, it…”
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Phage selection restores antibiotic sensitivity in MDR Pseudomonas aeruginosa by Chan, Benjamin K., Sistrom, Mark, Wertz, John E., Kortright, Kaitlyn E., Narayan, Deepak, Turner, Paul E.

“…Increasing prevalence and severity of multi-drug-resistant (MDR) bacterial infections has necessitated novel antibacterial strategies. Ideally, new approaches…”
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Rapid construction of metabolite biosensors using domain-insertion profiling by Nadler, Dana C., Morgan, Stacy-Anne, Flamholz, Avi, Kortright, Kaitlyn E., Savage, David F.

“…Single-fluorescent protein biosensors (SFPBs) are an important class of probes that enable the single-cell quantification of analytes in vivo . Despite…”
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Selection for Phage Resistance Reduces Virulence of Shigella flexneri by Kortright, Kaitlyn E, Done, Rachel E, Chan, Benjamin K, Souza, Valeria, Turner, Paul E

“…There is an increasing interest in phage therapy as an alternative to antibiotics for treating bacterial infections, especially using phages that select for…”
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Arms race and fluctuating selection dynamics in Pseudomonas aeruginosa bacteria coevolving with phage OMKO1 by Kortright, Kaitlyn E., Chan, Benjamin K., Evans, Benjamin R., Turner, Paul E.

“…Experimental evolution studies have examined coevolutionary dynamics between bacteria and lytic phages, where two models for antagonistic coevolution dominate:…”
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Evolution of Bacterial Cross-Resistance to Lytic Phages and Albicidin Antibiotic by Kortright, Kaitlyn E, Doss-Gollin, Simon, Chan, Benjamin K, Turner, Paul E

“…Due to concerns over the global increase of antibiotic-resistant bacteria, alternative antibacterial strategies, such as phage therapy, are increasingly being…”
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Hydrogen peroxide vapor decontamination of N95 respirators for reuse by Kenney, Patrick A, Chan, Benjamin K, Kortright, Kaitlyn E, Cintron, Margaret, Russi, Mark, Epright, Jacqueline, Lee, Lorraine, Balcezak, Thomas J, Havill, Nancy L, Martinello, Richard A

“…The coronavirus disease 2019 (COVID-19) pandemic has led to global shortages of N95 respirators. Reprocessing of used N95 respirators may provide a higher…”
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Optimized preparation pipeline for emergency phage therapy against Pseudomonas aeruginosa at Yale University by Würstle, Silvia, Lee, Alina, Kortright, Kaitlyn E., Winzig, Franziska, An, William, Stanley, Gail L., Rajagopalan, Govindarajan, Harris, Zach, Sun, Ying, Hu, Buqu, Blazanin, Michael, Hajfathalian, Maryam, Bollyky, Paul L., Turner, Paul E., Koff, Jonathan L., Chan, Benjamin K.

“…Bacteriophage therapy is one potential strategy to treat antimicrobial resistant or persistent bacterial infections, and the year 2021 marked the centennial of…”
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Programmed Ribosomal Frameshifting Mediates Expression of the α-Carboxysome by Chaijarasphong, Thawatchai, Nichols, Robert J., Kortright, Kaitlyn E., Nixon, Charlotte F., Teng, Poh K., Oltrogge, Luke M., Savage, David F.

“…Many bacteria employ a protein organelle, the carboxysome, to catalyze carbon dioxide fixation in the Calvin Cycle. Only 10 genes from Halothiobacillus…”
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Salphage: salvage bacteriophage therapy for a recalcitrant Klebsiella pneumoniae prosthetic shoulder infection - a case report by Doub, James B, Shishido, Akira, Srikumaran, Uma, Haskoor, John, Tran-Nguyen, Phuong, Lee, Myounghee, Würstle, Silvia, Lee, Alina, Kortright, Kaitlyn, Chan, Benjamin K

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Extending the lifetime of antibiotics: how can phage therapy help? by Chan, Benjamin K, Brown, Kevin, Kortright, Kaitlyn E, Mao, Stephanie, Turner, Paul E

“…[...]evolved modifications of surface-expressed receptors may be beneficial to bacteria in the presence of phage, but deleterious in their absence(9). [...]the…”
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The Use of Bacteriophages and Immunological Monitoring for the Treatment of a Case of Chronic Septicemic Cutaneous Ulcerative Disease in a Loggerhead Sea Turtle Caretta caretta by Greene, Whitney, Chan, Benjamin, Bromage, Erin, Grose, Julianne H., Walsh, Cathy, Kortright, Kaitlyn, Forrest, Sue, Perry, Grace, Byrd, Lynne, Stamper, M. Andrew

“…In this case study, phage therapy was applied to treat a multidrug‐resistant case of septicemic cutaneous ulcerative disease (SCUD) caused by Citrobacter…”
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Phage Selection against Antibiotic Resistance or Virulence in Opportunistic Bacterial Pathogens by Kortright, Kaitlyn E

“…Bacteriophages (phages) are prolific, ubiquitous viruses that infect bacterial cells. Phages have proven to be invaluable tools of the biological sciences,…”
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Adenomatous polyposis coli mutants dominantly activate Hsf1-dependent cell stress pathways through inhibition of microtubule dynamics by Davies, Alexander E, Kortright, Kaitlyn, Kaplan, Kenneth B

“…Cancer cells up-regulate cell stress pathways, including the protein chaperone Hsp90. Increases in Hsp90 are believed "buffer" mutant protein activities…”
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