Search Results - "Korth, MJ"

Control of PKR Protein Kinase by Hepatitis C Virus Nonstructural 5A Protein: Molecular Mechanisms of Kinase Regulation by Gale, Michael, Blakely, Collin M., Kwieciszewski, Bart, Tan, Seng-Lai, Dossett, Michelle, Tang, Norina M., Korth, Marcus J., Polyak, Stephen J., Gretch, David R., Katze, Michael G.

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Evidence That Hepatitis C Virus Resistance to Interferon Is Mediated through Repression of the PKR Protein Kinase by the Nonstructural 5A Protein by Gale, Michael J., Korth, Marcus J., Tang, Norina M., Tan, Seng-Lai, Hopkins, Deborah A., Dever, Thomas E., Polyak, Stephen J., Gretch, David R., Katze, Michael G.

“…Hepatitis C virus (HCV) is the major cause of non-A non-B hepatitis and a leading cause of liver dysfunction worldwide. While the current therapy for chronic…”
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Gene Expression Patterns That Correlate With Hepatitis C and Early Progression to Fibrosis in Liver Transplant Recipients by Smith, Maria W., Walters, Kathie–Anne, Korth, Marcus J., Fitzgibbon, Matthew, Proll, Sean, Thompson, Jill C., Yeh, Matthew M., Shuhart, Margaret C., Furlong, Jeffrey C., Cox, Paula P., Thomas, David L., Phillips, John D., Kushner, James P., Fausto, Nelson, Carithers, Robert L., Katze, Michael G.

“…Background & Aims: Liver transplant recipients infected with hepatitis C virus (HCV) develop recurrent hepatitis soon after transplantation and, in some cases,…”
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Gene Expression Profiling of the Cellular Transcriptional Network Regulated by Alpha/Beta Interferon and Its Partial Attenuation by the Hepatitis C Virus Nonstructural 5A Protein by Geiss, Gary K, Carter, Victoria S, He, Yupeng, Kwieciszewski, Bartlomiej K, Holzman, Ted, Korth, Marcus J, Lazaro, Catherine A, Fausto, Nelson, Bumgarner, Roger E, Katze, Michael G

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High-Throughput Screening of the Yeast Kinome: Identification of Human Serine/Threonine Protein Kinases That Phosphorylate the Hepatitis C Virus NS5A Protein by Coito, Carlos, Diamond, Deborah L, Neddermann, Petra, Korth, Marcus J, Katze, Michael G

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Hijacking of the host-cell response and translational control during influenza virus infection by Kash, John C., Goodman, Alan G., Korth, Marcus J., Katze, Michael G.

“…Influenza virus is a major public health problem with annual deaths in the US of 36,000 with pandemic outbreaks, such as in 1918, resulting in deaths exceeding…”
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Unlocking the mysteries of virus-host interactions: does functional genomics hold the key? by Korth, Marcus J, Katze, Michael G

“…The interactions between viruses and the cells they infect are complex and multifaceted. While viruses strive to usurp cellular functions to their advantage,…”
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Analysis of the Macaca mulatta transcriptome and the sequence divergence between Macaca and human by Magness, Charles L, Fellin, P Campion, Thomas, Matthew J, Korth, Marcus J, Agy, Michael B, Proll, Sean C, Fitzgibbon, Matthew, Scherer, Christina A, Miner, Douglas G, Katze, Michael G, Iadonato, Shawn P

“…We report the initial sequencing and comparative analysis of the Macaca mulatta transcriptome. Cloned sequences from 11 tissues, nine animals, and three…”
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Functional gene analysis of individual response to challenge of SIVmac239 in M. mulatta PBMC culture by Thomas, Matthew J., Agy, Michael B., Proll, Sean C., Paeper, Bryan W., Li, Yu, Jensen, Kara L., Korth, Marcus J., Katze, Michael G.

“…It has previously been shown in macaques that individual animals exhibit varying responses to challenge with the same strain of SIV. We attempted to elucidate…”
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Evading the interferon response: hepatitis C virus and the interferon-induced protein kinase, PKR by Korth, M J, Katze, M G

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Control of PERK eIF2[alpha] kinase activity by the endoplasmic reticulum stress-induced molecular chaperone P58 super(IPK) by Yan, W, Frank, CL, Korth, MJ, Sopher, B L, Novoa, I, Ron, D, Katze, M G

“…P58 super(IPK) is an Hsp40 family member known to inhibit the interferon (IFN)-induced, double-stranded RNA-activated, eukaryotic initiation factor 2[alpha]…”
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Repression of the PKR protein kinase by the hepatitis C virus NS5A protein: a potential mechanism of interferon resistance by Gale, Jr, Michael J, Korth, Marcus J, Katze, Michael G

“…Background: Chronic infection with hepatitis C virus (HCV) is associated with progressive liver damage, including the development of cirrhosis and…”
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Inhibition of double-stranded RNA- and tumor necrosis factor alpha-mediated apoptosis by tetratricopeptide repeat protein and cochaperone P58(IPK) by Tang, N M, Korth, M J, Gale, Jr, M, Wambach, M, Der, S D, Bandyopadhyay, S K, Williams, B R, Katze, M G

“…P58(IPK) is a tetratricopeptide repeat-containing cochaperone that is involved in stress-activated cellular pathways and that inhibits the activity of protein…”
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Interferon Inhibits the Replication of HIV-1, SIV, and SHIV Chimeric Viruses by Distinct Mechanisms by Korth, Marcus J., Taylor, Matthew D., Katze, Michael G.

“…Interferon (IFN) treatment of lentivirus-infected cells substantially reduces virus replicationin vitro. Although the replication of both HIV-1 and simian…”
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Cloning, expression, and cellular localization of the oncogenic 58-kDa inhibitor of the RNA-activated human and mouse protein kinase by Korth, Marcus J., Lyons, Christopher N., Wambach, Marlene, Katze, Michael G.

“…The 58-kDa inhibitor of the interferon-induced double-stranded RNA-activated protein kinase (PKR) is a cellular protein that is activated during influenza…”
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Interferon Treatment Inhibits the Replication of Simian Immunodeficiency Virus at an Early Stage: Evidence for a Block between Attachment and Reverse Transcription by Taylor, Matthew D., Korth, Marcus J., Katze, Michael G.

“…Interferon (IFN) dramatically reduces both SIV and HIV-1 replicationin vitro. However, we previously found that whereas IFN treatment of SIV-infected cells…”
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Inhibition of Double-Stranded RNA- and Tumor Necrosis Factor Alpha-Mediated Apoptosis by Tetratricopeptide Repeat Protein and Cochaperone P58 super(IPK) by Tang, N M, Korth, MJ, Gale, M, Wambach, M, Der, S D, Bandyopadhyay, S K, Williams, BRG, Katze, M G

“…P58 super(IPK) is a tetratricopeptide repeat- containing cochaperone that is involved in stress-activated cellular pathways and that inhibits the activity of…”
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Chromosomal assignment of the gene encoding the human 58-kDa inhibitor (PRKRI) of the interferon-induced dsRNA-activated protein kinase to chromosome 13q32 by KORTH, M. J, EDELHOFF, S, DISTECHE, C. M, KATZE, M. G

“…The 58-kDa inhibitor (p58) of the interferon-induced dsRNA-activated protein kinase (PKR) is a cellular protein recruited by the influenza virus to…”
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Epithelial cell invasion by bovine septicemic Escherichia coli by Korth, M.J, Lara, J.C, Moseley, S.L

“…Little is known regarding the pathogenesis of Escherichia coli-induced septicemic colibacillosis of calves. To understand the mechanism by which these strains…”
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Functional expression of heterologous fimbrial subunits mediated by the F41, K88, and CS31A determinants of Escherichia coli by KORTH, M. J, APOSTOL, J. M, MOSELEY, S. L

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