Search Results - "Korte, F."
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Growth of Engineered Human Myocardium With Mechanical Loading and Vascular Coculture
Published in Circulation research (24-06-2011)“…RATIONALE:The developing heart requires both mechanical load and vascularization to reach its proper size, yet the regulation of human heart growth by these…”
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2
The embryonic myosin R672C mutation that underlies Freeman-Sheldon syndrome impairs cross-bridge detachment and cycling in adult skeletal muscle
Published in Human molecular genetics (15-06-2015)“…Distal arthrogryposis is the most common known heritable cause of congenital contractures (e.g. clubfoot) and results from mutations in genes that encode…”
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3
Particle size traces modern Saharan dust transport and deposition across the equatorial North Atlantic
Published in Atmospheric chemistry and physics (04-11-2016)“…Mineral dust has a large impact on regional and global climate, depending on its particle size. Especially in the Atlantic Ocean downwind of the Sahara, the…”
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4
Physiological function and transplantation of scaffold-free and vascularized human cardiac muscle tissue
Published in Proceedings of the National Academy of Sciences - PNAS (29-09-2009)“…Success of human myocardial tissue engineering for cardiac repair has been limited by adverse effects of scaffold materials, necrosis at the tissue core, and…”
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5
How newcomers learn the social norms of an organization: A case study of the socialization of newly hired engineers
Published in Human resource development quarterly (01-09-2009)“…Current scholarship views organizational socialization as a learning process that is primarily the responsibility of the newcomer. Yet recent learning research…”
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6
Tropical rains controlling deposition of Saharan dust across the North Atlantic Ocean
Published in Geophysical research letters (16-03-2020)“…Mineral dust plays an important role in the atmospheric radiation budget as well as in the ocean carbon cycle through fertilization and by ballasting of…”
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7
Downward particle fluxes of biogenic matter and Saharan dust across the equatorial North Atlantic
Published in Atmospheric chemistry and physics (16-05-2017)“…Massive amounts of Saharan dust are blown from the coast of northern Africa across the Atlantic Ocean towards the Americas each year. This dust has, depending…”
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8
Thin filament incorporation of an engineered cardiac troponin C variant (L48Q) enhances contractility in intact cardiomyocytes from healthy and infarcted hearts
Published in Journal of molecular and cellular cardiology (01-07-2014)“…Abstract Many current pharmaceutical therapies for systolic heart failure target intracellular [Ca 2 + ] ([Ca 2 + ]i ) metabolism, or cardiac troponin C (cTnC)…”
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9
Upregulation of cardiomyocyte ribonucleotide reductase increases intracellular 2 deoxy-ATP, contractility, and relaxation
Published in Journal of molecular and cellular cardiology (01-12-2011)“…Abstract We have previously demonstrated that substitution of ATP with 2 deoxy-ATP (dATP) increased the magnitude and rate of force production at all levels of…”
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10
Formation of microbumps and nanojets on gold targets by femtosecond laser pulses
Published in Applied physics. A, Materials science & processing (01-09-2004)“…Femtosecond laser-induced sub-wavelength microstructuring of a thin gold layer coated onto a quartz glass substrate is investigated. Formation of microbumps…”
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Prevascularized microtemplated fibrin scaffolds for cardiac tissue engineering applications
Published in Tissue engineering. Part A (01-04-2013)“…Myocardial infarction (MI) causes significant cell loss and damage to myocardium. Cell-based therapies for treatment of MI aim to remuscularize the resultant…”
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12
Loaded Shortening, Power Output, and Rate of Force Redevelopment Are Increased With Knockout of Cardiac Myosin Binding Protein-C
Published in Circulation research (17-10-2003)“…ABSTRACT—Myosin binding protein-C (MyBP-C) is localized to the thick filaments of striated muscle where it appears to have both structural and regulatory…”
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13
Coccolithophore fluxes in the open tropical North Atlantic: influence of thermocline depth, Amazon water, and Saharan dust
Published in Biogeosciences (17-10-2017)“…Coccolithophores are calcifying phytoplankton and major contributors to both the organic and inorganic oceanic carbon pumps. Their export fluxes, species…”
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14
Nanotexturing of gold films by femtosecond laser-induced melt dynamics
Published in Applied physics. A, Materials science & processing (01-07-2005)Get full text
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15
Sarcomere length dependence of rat skinned cardiac myocyte mechanical properties: dependence on myosin heavy chain
Published in The Journal of physiology (01-06-2007)“…The effects of sarcomere length (SL) on sarcomeric loaded shortening velocity, power output and rates of force development were examined in rat skinned cardiac…”
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Power output is linearly related to MyHC content in rat skinned myocytes and isolated working hearts
Published in American journal of physiology. Heart and circulatory physiology (01-08-2005)“…The amount of work the heart can perform during ejection is governed by the inherent contractile properties of individual myocytes. One way to alter…”
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17
Transcription factor CHF1/Hey2 regulates EC coupling and heart failure in mice through regulation of FKBP12.6
Published in American journal of physiology. Heart and circulatory physiology (01-05-2012)“…Heart failure is a leading cause of morbidity and mortality in Western society. The cardiovascular transcription factor CHF1/Hey2 has been linked to…”
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18
Towards nanostructuring with femtosecond laser pulses
Published in Applied physics. A, Materials science & processing (01-07-2003)“…Detailed investigations of the possibilities for using femtosecond lasers for the nanostructuring of metal layers and transparent materials are reported. The…”
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19
Enhanced Ca2+ binding of cardiac troponin reduces sarcomere length dependence of contractile activation independently of strong crossbridges
Published in American journal of physiology. Heart and circulatory physiology (01-10-2012)“…Calcium sensitivity of the force-pCa relationship depends strongly on sarcomere length (SL) in cardiac muscle and is considered to be the cellular basis of the…”
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Loaded shortening and power output in cardiac myocytes are dependent on myosin heavy chain isoform expression
Published in American journal of physiology. Heart and circulatory physiology (01-09-2001)“…The purpose of this study was to examine the role of myosin heavy chain (MHC) in determining loaded shortening velocities and power output in cardiac myocytes…”
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