Search Results - "Kors, Suzan"

Regulation of Proteasome Activity by (Post-)transcriptional Mechanisms by Kors, Suzan, Geijtenbeek, Karlijne, Reits, Eric, Schipper-Krom, Sabine

“…Intracellular protein synthesis, folding, and degradation are tightly controlled processes to ensure proper protein homeostasis. The proteasome is responsible…”
Get full text

The diversity of ACBD proteins – From lipid binding to protein modulators and organelle tethers by Islinger, Markus, Costello, Joseph L., Kors, Suzan, Soupene, Eric, Levine, Timothy P., Kuypers, Frans A., Schrader, Michael

“…Members of the large multigene family of acyl-CoA binding domain containing proteins (ACBDs) share a conserved motif required for binding of Coenzyme A…”
Get full text

Multiple Ways to Keep FFAT Under Control by Kors, Suzan, Schrader, Michael, Costello, Joseph L.

“…Peroxisomes and the ER are closely inter-connected organelles, which collaborate in the metabolism of lipids. In a recent research paper in the Journal of Cell…”
Get full text

VAP Proteins - From Organelle Tethers to Pathogenic Host Interactors and Their Role in Neuronal Disease by Kors, Suzan, Costello, Joseph L, Schrader, Michael

“…Vesicle-associated membrane protein (VAMP)-associated proteins (VAPs) are ubiquitous ER-resident tail-anchored membrane proteins in eukaryotic cells. Their…”
Get full text

A Functional SMAD2/3 Binding Site in the PEX11β Promoter Identifies a Role for TGFβ in Peroxisome Proliferation in Humans by Azadi, Afsoon S., Carmichael, Ruth E., Kovacs, Werner J., Koster, Janet, Kors, Suzan, Waterham, Hans R., Schrader, Michael

“…In mammals, peroxisomes perform crucial functions in cellular metabolism, signaling and viral defense which are essential to the viability of the organism…”
Get full text

Assessing Peroxisomal Protein Interaction by Immunoprecipitation by Kors, Suzan, Schrader, Michael

“…Organelles physically interact with each other via protein tethering complexes that bridge the opposing membranes. Organelle membrane contacts are highly…”
Get more information

Controlling contacts—Molecular mechanisms to regulate organelle membrane tethering by Kors, Suzan, Kurian, Smija M., Costello, Joseph L., Schrader, Michael

“…In recent years, membrane contact sites (MCS), which mediate interactions between virtually all subcellular organelles, have been extensively characterized and…”
Get full text

Regulating peroxisome-ER contacts via the ACBD5-VAPB tether by FFAT motif phosphorylation and GSK3β by Kors, Suzan, Hacker, Christian, Bolton, Chloe, Maier, Renate, Reimann, Lena, Kitchener, Emily J A, Warscheid, Bettina, Costello, Joseph L, Schrader, Michael

“…Peroxisomes and the endoplasmic reticulum (ER) cooperate in cellular lipid metabolism. They form membrane contacts through interaction of the peroxisomal…”
Get full text

New insights into the functions of ACBD4/5-like proteins using a combined phylogenetic and experimental approach across model organisms by Kors, Suzan, Schuster, Martin, Maddison, Daniel C., Kilaru, Sreedhar, Schrader, Tina A., Costello, Joseph L., Islinger, Markus, Smith, Gaynor A., Schrader, Michael

“…Acyl-CoA binding domain-containing proteins (ACBDs) perform diverse but often uncharacterised functions linked to cellular lipid metabolism. Human ACBD4 and…”
Get full text

Peroxisomes : novel findings and future directions by Pedrosa, Ana G., Reglinski, Katharina, Lismont, Celien, Kors, Suzan, Costello, Joseph, Rodrigues, Tony A., Marques, Mariana, Linka, Nicole, Argyriou, Catherine, Weinhofer, Isabelle, Kocherlakota, Sai, Riccio, Victoria, Ferreira, Vanessa, Di Cara, Francesca, Ferreira, Ana Rita, Francisco, Tânia, Azevedo, Jorge E., Ribeiro, Daniela

Get full text

Insulin-Degrading Enzyme Efficiently Degrades polyQ Peptides but not Expanded polyQ Huntingtin Fragments by Geijtenbeek, Karlijne W, Aranda, Angela Santiago, Sanz, Alicia Sanz, Janzen, Jolien, Bury, Aleksandra E, Kors, Suzan, Al Amery, Nur, Schmitz, Nina C M, Reits, Eric A J, Schipper-Krom, Sabine

“…Huntington's disease is an inheritable autosomal dominant disorder caused by an expanded CAG trinucleotide repeat within the Huntingtin gene, leading to a…”
Get more information