Search Results - "Korotkevych, N V"

EFFECT OF DIPHTHERIA TOXIN T-DOMAIN ON ENDOSOMAL pH by Labyntsev, A J, Korotkevych, N V, Kolybo, D V, Komisarenko, S V

“…A key step in the mode of cytotoxic action of diphtheria toxin (DT) is the transfer of its catalytic domain (Cd) from endosomes into the cytosol. The main…”
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Effect of the T-domain on intracellular transport of diphtheria toxin by Labyntsev, A J, Kolybo, D V, Yurchenko, E S, Kaberniuk, A A, Korotkevych, N V, Komisarenko, S V

“…Subunit B of diphtheria toxin (DT), which consists of two domains: R (receptor-binding) and T (transmembrane), plays an important role in toxin-receptor…”
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Cell model for the study of receptor and regulatory functions of human proHB-EGF by Korotkevych, N V, Labyntsev, A Iu, Manoĭlov, K Iu, Krynina, O I, Diachenko, K V, Kolybo, D V, Komisarenko, S V

“…Developing of new models and approaches, particularly with fluorescent techniques, for investigation of intracellular transport of proHB-EGF and its…”
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Influence of human HB-EGF secreted form on cells with different EGFR and ErbB4 quantity by Krynina, O. I., Korotkevych, N. V., Labyntsev, A. J., Romaniuk, S. I., Kolybo, D. V., Komisarenko, S. V.

“…HB-EGF is one of the most potent ligands of EGFR and ErbB4 receptors. This growth factor plays a pivotal role in many cellular processes, but its effect…”
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Particular Features of Diphtheria Toxin Internalization by Resistant and Sensitive Mammalian Cells by Manoilov, K. Y., Labyntsev, A. Ju, Korotkevych, N. V., Maksymovych, I. S., Kolybo, D. V., Komisarenko, S. V.

“…Several mammalian species are resistant to diphtheria toxin (DT). The DT receptor, proHB-EGF in resistant and sensitive species, has a different primary…”
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Enhancement of internalization of diphtheria toxin recombinant fragments in sensitive cells mediated by toxin’s T-domain by Manoilov, K. Yu, Labyntsev, A. J., Korotkevych, N. V., Kolybo, D. V.

“…Subunit B of diphtheria toxin (DT) and its R-domain differ by the presence of T-domain. The aim of the present work was to analyze the interaction of these…”
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Heparin-binding EGF-like growth factor: mechanisms of biological activity and potential therapeutic applications by Dronko, L. M., Lutsenko, T. M., Korotkevych, N. V., Vovk, I. O., Zhukova, D. A., Romaniuk, S. I., Siromolot, A. A., Labyntsev, A. J., Kolybo, D. V.

“…The diphtheria toxin receptor on sensitive mammalian cells is known as the membrane anchored precursor of heparin-binding EGF-like growth factor (HB-EGF). When…”
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OBTAINING OF RECOMBINANT ANALOGUE OF HUMAN SHB-EGF USING OF TRANSPOSON-TRANSPOSASE GENETIC SYSTEM by N. V., Korotkevych

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INTERACTION OF RECOMBINANT DIPHTHERIA TOXOIDS WITH CELLULAR RECEPTORS in vitro by K. Yu. Manoilov, A. Ju. Labyntsev, N. V. Korotkevych, D. V. Kolibo, S. V. Komisarenko

“…The aim of the research was to compare in vitro characteristics of reception of the natural diphtheria toxin — DT and its nontoxic recombinant analogs —…”
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INTERACTION OF RECOMBINANT DIPHTHERIA TOXOIDS WITH CELLULAR RECEPTORS in vitro by Manoilov, K Yu, Labyntsev, A Ju, Korotkevych, N V, Kolibo, D V, Komisarenko, S V

“…The aim of the research was to compare in vitro characteristics of reception of the natural diphtheria toxin -- DT and its nontoxic recombinant analogs --…”
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OBTAINING OF RECOMBINANT ANALOGUE OF HUMAN SHB-EGF BY TRANSPOSON-TRANSPOSASE GENETIC SYSTEM by Korotkevych, N V, Labyntsev, A Yu, Kolybo, D V, Komisarenko, S V

“…The goal of this work was to obtain the recombinant soluble form of heparin-binding EGF-like growth factor sHB-EGF in eukaryotic cells based on transposon…”
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Recombinant fluorescent models for studying the diphtheria toxin by Labyntsev, A. J., Korotkevych, N. V., Manoilov, K. J., Kaberniuk, A. A., Kolybo, D. V., Komisarenko, S. V.

“…Diphtheria toxin is a major factor of the pathogenicity of the causative agent of diphtheria Corynebacterium . Due to a small size, it is of considerable…”
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Cytotoxicity of the B subunit of diphtheria toxin to human histocytic lymphoma U937 by Korotkevych, N V, Labyntsev, A Iu, Kaberniuk, A A, Oliĭnyk, O S, Romaniuk, S I, Kolybo, D V, Komisarenko, S V

“…The B subunit of diphtheria toxin (DT) is responsible for interaction with receptor on the cell surface and translocation of the catalytically active A subunit…”
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Construction of immune library of murine immunoglobulin genes and screening of single-chain Fv-antibodies specific to diphtheria toxin B subunit by Oliĭnyk, O S, Kaberniuk, A A, Redchuk, T A, Korotkevych, N V, Labyntsev, A Iu, Romaniuk, S I, Kolybo, D V, Komisarenko, S V

“…The aim of this work was to obtain the panel of recombinant single-chain Fv-antibodies against diphtheria toxin B subunit, the main diagnostic and pathogenic…”
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Fluorescent derivatives of diphtheria toxin subunit B and their interaction with Vero cells by Kaberniuk, A A, Labyntsev, A Iu, Kolybo, D V, Oliĭnyk, O S, Redchuk, T A, Korotkevych, N V, Horchev, V F, Karakhim, S O, Komisarenko, S V

“…Diphtheria toxin's B subunit provides toxin interaction with its receptor on the cell surface and translocation of toxin's A subunit from endosome to cytozole…”
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