Search Results - "Korotchenko, Evgeniia"
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Synergistic effects of dendritic cell targeting and laser-microporation on enhancing epicutaneous skin vaccination efficacy
Published in Journal of controlled release (28-11-2017)“…Due to its unique immunological properties, the skin is an attractive target tissue for allergen-specific immunotherapy. In our current work, we combined a…”
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Mechanisms of Particles in Sensitization, Effector Function and Therapy of Allergic Disease
Published in Frontiers in immunology (30-06-2020)“…Humans have always been in contact with natural airborne particles from many sources including biologic particulate matter (PM) which can exhibit allergenic…”
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Functionalized multifunctional nanovaccine for targeting dendritic cells and modulation of immune response
Published in International journal of pharmaceutics (25-01-2021)“…[Display omitted] Multifunctional gelatin nanoparticles modified by NIR-emitting gold/silver alloy nanoclusters and loaded with ovalbumin (OVA) as a model…”
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Mast cells and γδ T cells are largely dispensable for adaptive immune responses after laser-mediated epicutaneous immunization
Published in Vaccine (29-01-2020)“…[Display omitted] The skin resembles an attractive target for vaccination due to its accessibility and abundance of resident immune cells. Cells like γδ T…”
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Paired nicking-mediated COL17A1 reframing for junctional epidermolysis bullosa
Published in Molecular therapy (03-08-2022)“…Junctional epidermolysis bullosa (JEB) is a debilitating hereditary skin disorder caused by mutations in genes encoding laminin-332, type XVII collagen (C17),…”
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IL‐31 transgenic mice show reduced allergen‐induced lung inflammation
Published in European journal of immunology (01-01-2021)“…Interleukin‐31 (IL‐31) is a Th2 cell–derived cytokine that has been closely linked to pruritic skin inflammation. More recently, enhanced IL‐31 serum levels…”
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Laser‐facilitated epicutaneous immunotherapy with depigmented house dust mite extract alleviates allergic responses in a mouse model of allergic lung inflammation
Published in Allergy (Copenhagen) (01-05-2020)“…Background Skin‐based immunotherapy of type 1 allergies has recently been re‐investigated as an alternative for subcutaneous injections. In the current study,…”
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Laser‐facilitated epicutaneous immunotherapy with hypoallergenic beta‐glucan neoglycoconjugates suppresses lung inflammation and avoids local side effects in a mouse model of allergic asthma
Published in Allergy (Copenhagen) (01-01-2021)“…Background Allergen‐specific immunotherapy via the skin targets a tissue rich in antigen‐presenting cells, but can be associated with local and systemic side…”
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A novel vaccination platform for epicutaneous allergen-specific immunotherapy based on beta-glucan neoglycoconjugates
Published in The Journal of immunology (1950) (01-05-2019)“…Abstract Coupling of long chain carbohydrates to allergens can mask IgE epitopes and thus reduce the allergenicity of the neoglycoconjugates. The resulting…”
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