Search Results - "Korostoff, J"
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Photobiomodulation of Gingival Cells Challenged with Viable Oral Microbes
Published in Journal of dental research (01-07-2024)“…The oral cavity, a unique ecosystem harboring diverse microorganisms, maintains health through a balanced microflora. Disruption may lead to disease,…”
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Cell Junction Remodeling in Gingival Tissue Exposed to a Microbial Toxin
Published in Journal of dental research (01-06-2013)“…The gingival epithelium plays a key role in protecting the supporting structures of the teeth from bacteria and their products. In ex vivo experiments, we…”
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3
Cytolethal Distending Toxin Damages the Oral Epithelium of Gingival Explants
Published in Journal of dental research (01-07-2011)“…The cytolethal distending toxin (Cdt), expressed by the periodontal pathogen Aggregatibacter actinomycetemcomitans, inhibits the proliferation of cultured…”
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Variants of Porphyromonas gingivalis lipopolysaccharide alter lipidation of autophagic protein, microtubule-associated protein 1 light chain 3, LC3
Published in Molecular oral microbiology (01-12-2016)“…Summary Porphyromonas gingivalis often subverts host cell autophagic processes for its own survival. Our previous studies document the association of the cargo…”
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5
Targeted Inhibition of CD133+ Cells in Oral Cancer Cell Lines
Published in Journal of dental research (01-05-2011)“…Resistance to treatment and the appearance of secondary tumors in head and neck squamous cell carcinomas (HNSCC) have been attributed to the presence of cells…”
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Mechanical forces alter extracellular matrix synthesis by human periodontal ligament fibroblasts
Published in Journal of periodontal research (01-11-1998)“…Periodontal ligament fibroblasts (PDLFs) are a heterogeneous population of cells that are involved in the normal maintenance, repair and regeneration of both…”
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Heparan Sulfate Interacting Protein (HIP/L29) Negatively Regulates Growth Responses to Basic Fibroblast Growth Factor in Gingival Fibroblasts
Published in Journal of dental research (01-04-2002)“…Basic fibroblast growth factor (bFGF) modulates gingival growth, and its release from heparan sulfate (HS) in the extracellular matrix (ECM) governs local…”
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Beyond the specific plaque hypothesis: are highly leukotoxic strains of Actinobacillus actinomycetemcomitans a paradigm for periodontal pathogenesis?
Published in Critical reviews in oral biology and medicine (01-01-2001)“…Actinobacillus actinomycetemcomitans is a facultative anaerobe implicated in a variety of periodontal diseases. Its presence is most closely associated with…”
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Analysis of In Situ Protease Activity in Chronic Adult Periodontitis Patients: Expression of Activated MMP‐2 and a 40 kDa Serine Protease
Published in Journal of periodontology (1970) (01-03-2000)“…Background: Periodontitis is characterized by extensive destruction of the gingival tissues and associated supporting structures of the teeth. Although the…”
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Neonatal exposure to thymotropic gross murine leukemia virus induces virus-specific immunologic nonresponsiveness
Published in The Journal of experimental medicine (01-12-1990)“…Neonatal exposure to Gross murine leukemia virus results in a profound inhibition of the virus-specific T and B cell responses of adult animals. Animals…”
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A novel digital approach for fixed full-mouth implant-supported rehabilitations: A case report
Published in Journal of clinical and experimental dentistry (01-09-2020)“…Successful rehabilitation of a patient’s entire dentition with implant-supported fixed prostheses requires restoration of function, esthetics and comfort. To…”
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Evaluation of the humoral immune response to the cytolethal distending toxin of Aggregatibacter actinomycetemcomitans Y4 in subjects with localized aggressive periodontitis
Published in Oral microbiology and immunology (01-04-2009)“…Introduction: Cytolethal distending toxin (Cdt) is potentially one of several virulence factors of Aggregatibacter actinomycetemcomitans, the prime…”
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A Multidisciplinary Approach to the Diagnosis and Treatment of Early‐Onset Periodontitis: A Case Report
Published in Journal of periodontology (1970) (01-01-2001)“…Background: The diagnosis and treatment of earlyonset forms of periodontitis (EOP) represent a major challenge to periodontists. In this case report, we…”
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The interaction between RTX toxins and target cells
Published in Trends in Microbiology (01-09-1999)“…RTX toxins are important virulence factors produced by a wide range of Gram-negative bacteria. They fall into two categories: the hemolysins, which affect a…”
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Patterns of Ig V region expression among neonatal hemagglutinin- responsive B cells. Evidence for non-random VH gene representation during later stages of development
Published in The Journal of immunology (1950) (15-11-1988)“…Hybridoma libraries were established whose specificities reflect those within the BALB/c hemagglutinin-responsive B cell repertoire at 1 or 2 wk of age. These…”
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Impaired immune responsiveness is an essential component in persistent central nervous system infection with gross murine leukemia virus
Published in Journal of neuroimmunology (01-10-1991)“…Exposure of newborn mice to Gross murine leukemia virus (GMuLV) results in persistent viral infection of the central nervous system (CNS) white matter. Animals…”
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RTX toxins recognize a beta 2 integrin on the surface of human target cells
Published in The Journal of biological chemistry (28-11-1997)“…Actinobacillus actinomycetemcomitans leukotoxin and Escherichia coli alpha -hemolysin are RTX toxins that kill human immune cells. We have obtained a…”
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Characterization of point mutations in the cdtA gene of the cytolethal distending toxin of Actinobacillus actinomycetemcomitans
Published in Molecular microbiology (01-12-2005)“…Summary The Cdt is a family of gram‐negative bacterial toxins that typically arrest eukaryotic cells in the G0/G1 or G2/M phase of the cell cycle. The toxin is…”
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Manipulation of the immune response by foreign gene expression in the thymus
Published in Leukemia (01-10-1995)“…Retroviral gene transfer vectors have been developed for optimal in vivo gene therapy. Ideally, these vectors should target gene expression specifically to…”
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Resistance of Human Periodontal Ligament Fibroblasts to the Cytolethal Distending Toxin of Actinobacillus actinomycetemcomitans
Published in Journal of periodontology (1970) (01-07-2005)“…Background: The cytolethal distending toxin (CDT) of Actinobacillus actinomycetemcomitans is a typical member of this Gram‐negative bacterium holotoxin family…”
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