Search Results - "Koroleva, Marina"
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The novel coronary artery disease risk gene JCAD/KIAA1462 promotes endothelial dysfunction and atherosclerosis
Published in European heart journal (01-08-2019)“…Recent genome-wide association studies (GWAS) have identified that the JCAD locus is associated with risk of coronary artery disease (CAD) and myocardial…”
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Tannic acid as a plant-derived polyphenol exerts vasoprotection via enhancing KLF2 expression in endothelial cells
Published in Scientific reports (27-07-2017)“…The transcription factor Kruppel-like factor 2 (KLF2) is a critical anti-inflammatory and anti-atherogenic molecule in vascular endothelium. Enhancing KLF2…”
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SIRT6 protects against endothelial dysfunction and atherosclerosis in mice
Published in Aging (Albany, NY.) (30-05-2016)“…SIRT6 is an important member of sirtuin family that represses inflammation, aging and DNA damage, three of which are causing factors for endothelial…”
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Controlling pore sizes in highly porous Poly(Styrene-Divinylbenzene) sponges for preferable oil sorption
Published in Polymer testing (01-08-2019)“…Highly porous polymeric materials with an open and interconnected pore structure are prospective for oil spill remediation. These materials are obtained by…”
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Co-Isolation of Cytokines and Exosomes: Implications for Immunomodulation Studies
Published in Frontiers in immunology (19-04-2021)“…Exosomes play a vital role in intercellular communication and their immunomodulatory potential have become an important focus in cancer research. Various…”
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Suberanilohydroxamic Acid as a Pharmacological Kruppel‐Like Factor 2 Activator That Represses Vascular Inflammation and Atherosclerosis
Published in Journal of the American Heart Association (01-12-2017)“…Background Kruppel‐like factor 2 (KLF2) is an important zinc‐finger transcription factor that maintains endothelial homeostasis by its anti‐inflammatory,…”
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A novel TRPV4-specific agonist inhibits monocyte adhesion and atherosclerosis
Published in Oncotarget (21-06-2016)“…TRPV4 ion channel mediates vascular mechanosensitivity and vasodilation. Here, we sought to explore whether non-mechanical activation of TRPV4 could limit…”
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Composites Composed of Hydrophilic and Hydrophobic Polymers, and Hydroxyapatite Nanoparticles: Synthesis, Characterization, and Study of Their Biocompatible Properties
Published in Journal of functional biomaterials (01-10-2021)“…The creation of artificial biocomposites consisting of biocompatible materials in combination with bioactive molecules is one of the main tasks of tissue…”
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Atheroprotective laminar flow inhibits Hippo pathway effector YAP in endothelial cells
Published in Translational research : the journal of laboratory and clinical medicine (01-10-2016)“…Abstract Atherosclerosis is a mechanobiology-related disease that preferentially develops in the aortic arch (AA) and arterial branches which are exposed to…”
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Preparation and characterization of lipid microcapsules coated with SiO2@Al2O3 core-shell nanoparticles as carries for lipophilic drug delivery
Published in Materials chemistry and physics (01-12-2017)“…Solid lipid microparticles coated by silica nanoparticles and loaded with lipophilic drugs: curcumin, hydrocortisone, nimesulide or α-tocopherol were…”
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Endothelial-specific YY1 governs sprouting angiogenesis through directly interacting with RBPJ
Published in Proceedings of the National Academy of Sciences - PNAS (03-03-2020)“…Angiogenesis, the formation of new blood vessels, is tightly regulated by gene transcriptional programs. Yin Ying 1 (YY1) is a ubiquitously distributed…”
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Myofibroblast-specific YY1 promotes liver fibrosis
Published in Biochemical and biophysical research communications (30-06-2019)“…Liver fibrosis is a common consequence of various chronic hepatitis and liver injuries. The myofibroblasts, through the accumulation of extracellular matrix…”
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Flow-dependent epigenetic regulation of IGFBP5 expression by H3K27me3 contributes to endothelial anti-inflammatory effects
Published in Theranostics (01-01-2018)“…: Atherosclerosis is a chronic inflammatory and epigenetic disease that is influenced by different patterns of blood flow. However, the epigenetic mechanism…”
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A Rapid Exosome Isolation Using Ultrafiltration and Size Exclusion Chromatography (REIUS) Method for Exosome Isolation from Melanoma Cell Lines
Published in Methods in molecular biology (Clifton, N.J.) (2021)“…Cells release extracellular vesicles (EVs) that can be detected both in vivo and in cell culture medium. Among EVs, exosomes are 50-150 nm vesicles that are…”
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Microemulsions and nanoemulsions modified with cationic surfactants for improving the solubility and therapeutic efficacy of loaded drug indomethacin
Published in Nanotechnology (09-04-2022)“…In this work, a noncovalent strategy was successfully used to modify colloidal stability and and efficacy of two amphiphilic formulations of the…”
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Abstract 006: Role of Endothelial YingYang1 in Controlling Angiogenetic Sprouting and Maturation
Published in Arteriosclerosis, thrombosis, and vascular biology (01-05-2018)“…Abstract only Angiogenesis is essential for growth and repair, and irregularity of angiogenesis contributes to numerous malignant, inflammatory and ischemic…”
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Abstract 12231: PECAM1 is Essential for Flow-mediated Gab1 Tyrosine Phosphorylation and Signaling in vitro and in vivo
Published in Circulation (New York, N.Y.) (10-11-2015)“…IntroductionImpaired activation of endothelial nitric oxide (NO) synthase (eNOS) and ensued NO production is a common mechanism of various cardiovascular…”
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Simulations of emulsion stabilization by silica nanoparticles
Published in Mendeleev communications (01-09-2017)“…[Display omitted] The Langevin dynamics simulation was used for studying the mechanisms of Pickering emulsion stabilization. The ranges of kinetically stable…”
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Highly porous polymeric sponges for oil sorption
Published in Mendeleev communications (01-03-2019)“…[Display omitted] Highly porous poly(styrene-co-divinylbenzene) sponges with highly hydrophobic internal surface, 95 vol% porosity and controllable pore sizes…”
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PECAM1 regulates flow-mediated Gab1 tyrosine phosphorylation and signaling
Published in Cellular signalling (01-03-2016)“…Endothelial dysfunction, characterized by impaired activation of endothelial nitric oxide (NO) synthase (eNOS) and ensued decrease of NO production, is a…”
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