Search Results - "Korogod, S.M."

Perturbed Ca2+-dependent signaling of DYT2 hippocalcin mutant as mechanism of autosomal recessive dystonia by Osypenko, D.S., Dovgan, A.V., Kononenko, N.I., Dromaretsky, A.V., Matvieienko, M., Rybachuk, O.A., Zhang, J., Korogod, S.M., Venkataraman, V., Belan, P.

“…A recent report of autosomal-recessive primary isolated dystonia (DYT2 dystonia) identified mutations in HPCA, a gene encoding a neuronal calcium sensor…”
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Role of the Plasma Membrane [Ca.sup.2+]-ATPase Pump in the Regulation of Rhythm Generation by an Interstitial Cell of Cajal: A Computational Study by Ellingson, P.J, Korogod, S.M, Kahl, T.M, Kulagina, I.B, Makedonsky, I.A, Cymbalyuk, G.S

“…Gastrointestinal motility is based on the rhythmic activity of interstitial cells of Cajal (ICCs). The ICC rhythm generation relies upon characteristic…”
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Differential back-invasion of a single complex dendrite of an abducens motoneuron by N-methyl- d-aspartate-induced oscillations: a simulation study by Korogod, S.M, Kopysova, I.L, Bras, H, Gogan, P, Tyc-Dumont, S

“…Intracellular recording of abducens motoneurons in vivo has shown that ionophoretic applications of N-methyl- d-aspartate produced long-lasting membrane…”
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Adverse Modulation of the Firing Patterns of Cold Receptors by Volatile Anesthetics Affecting Activation of TRPM8 Channels: a Modeling Study by Korogod, S. M., Maksymchuk, N. V., Demianenko, L. E., Vlasov, O. O., Cymbalyuk, G. S.

“…Transient receptor potential melastatin 8 channels (TRPM8s) are molecular sensors of temperature. They are expressed in primary afferent neurons (PANs) and…”
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Impact of the Ratio of Metabotropic and Ionotropic Components of Parasympathetic Action on the Excitability of a Urinary Bladder Smooth Muscle Cell: a Simulation Study by Kochenov, A. V., Korogod, S. M.

“…On a computer model of a smooth muscle cell (SMC) of the urinary bladder detrusor (UBD) having a corresponding set of ion channels and intracellular signaling…”
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Temperature Deactivation of the Depolarizing TRP Current as a Mechanism of Hypothermia-Related Inhibition of Neuronal Activity: a Model Study by Korogod, S. M., Demianenko, L. E.

“…Therapeutic neuroprotective hypothermia is becoming increasingly used to suppress abnormally high neuronal activity in the brain occurring under conditions of…”
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Hypoxic Depression of Pacemaker Activity of Interstitial Cells of Cajal: A Threat of Gastrointestinal Dysmotility and Necrosis. A Simulation Study by Korogod, S. M., Cymbalyuk, G. S., Makedonsky, I. A., Kulagina, I. B.

“…Hypoxic-ischemic injury is a known risk factor of necrotizing enterocolitis (NEC), an inflammatory bowel disease of neonates, one of the most common causes of…”
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Mathematical Model of the Calcium-Dependent Chloride Current in a Smooth Muscle Cell by Korogod, S. M., Kochenov, A. V.

“…Employing the Hodgkin-Huxley formalism, we have developed a mathematical model of the calcium-dependent chloride current on the basis of published experimental…”
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Hypothermic Suppression of Epileptiform Bursting Activity of a Hyppocampal Granule Neuron Possessing Thermosensitive TRP Channels (a Model Study: Biophysical and Clinical Aspects) by Demianenko, L. E., Poddubnaya, E. P., Makedonsky, I. A., Kulagina, I. B., Korogod, S. M.

“…Synchronous burst discharges of action potentials (APs) of neurons are typical manifestations of cerebral epileptiform activity; such discharges are reflected…”
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Biophysical Mechanism of Parasympathetic Excitation of Urinary Bladder Smooth Muscle Cells: a Simulation Study by Korogod, S. M., Kochenov, A. V., Makedonsky, I. A.

“…Using the Hodgkin-Huxley formalism, we developed a computer model of a smooth muscle cell (SMC) of the urinary bladder detrusor; the model included the main…”
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Biophysical Processes in a Urinary Bladder Detrusor Smooth Muscle Cell during Rehabilitation Stimulation of Parasympathetic Efferents: a Simulation Study by Kochenov, A. V., Poddubnaya, E. P., Makedonsky, I. A., Korogod, S. M.

“…In a computer model of an urinary bladder detrusor (UBD) smooth muscle cell (SMC), we investigated coupled changes in the membrane potential (MP), partial…”
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Organization of Activity of Hippocampal Pyramidal Neurons under Coactivation of Dendritic Glutamate- and GABA-Sensitive Receptors: a Simulation Study by Kulagina, I. B., Kaspirzhny, A. V., Korogod, S. M.

“…Using the model of a hippocampal pyramidal neuron with reconstructed dendritic arborization having active electrical properties of the membrane, we…”
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Biophysical Processes in a Urinary Bladder Detrusor Smooth Muscle Cell during Rehabilitation Electrostimulation: a Simulation Study by Kochenov, А. V., Poddubnaya, E. P., Makedonsky, I. A., Korogod, S. М.

“…The work was aimed at the search for approaches to solving the problem of biophysically reasonable selection of the parameters of electrical stimulation of…”
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Excitability Characteristics of a Urinary Bladder Detrusor Smooth Muscle Cell as a Basis for Choosing Parameters of Rehabilitation Electrostimulation: A Simulation Study by Kochenov, А. V., Poddubnaya, Ye. P., Makedonsky, I. A., Korogod, S. М.

“…Electrical stimulation targeted at smooth muscle cells (SMCs) of the urinary bladder detrusor (UBD) is used in a complex of rehabilitation procedures performed…”
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Dependence of Transformation of Intrinsic Rhythmic Impulse Activity of Neurons on Spatio-Temporal Organization of Synaptic Actions on Dendrites: A Simulation Study by Kulagina, I. B., Korogod, S. M.

“…The aim of the study to elucidate the biophysical mechanisms able to determine specific transformations of the patterns of output signals of neurons (neuronal…”
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Activity-Dependent Electrical Asymmetry of Dendrites as a Factor Determining the Repertoire of Intrinsic Firing Patterns of Neurons by Kaspirzhny, A. V., Кulagina, I. B., Коrogod, S. М.

“…Metrical asymmetry induced by the inequality of lengths and/or diameters of sister branches of dendrites is a common feature of complex dendritic arborizations…”
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Structure-Dependent Electrical and Concentration Processes in the Dendrites of Pyramidal Neurons of Superficial Neocortical Layers: Model Study by Kulagina, I. B., Kukushka, V. I., Korogod, S. M.

“…On mathematical models of pyramidal neurons localized in the neocortical layers 2/3, whose reconstructed dendritic arborization possessed passive linear or…”
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Conversion of Electrical and Synaptic Actions into Impulse Discharge Patterns in Purkinje Neurons with Active Dendrites: A Simulation Study by Кulagina, I. B., Launey, T., Кukushka, V. I., Коrogod, S. М.

“…We studied relations between the cell output spiking patterns (neuronal codes) and the intensity of input signals on a model of cerebellar Purkinje neuron with…”
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Impulse Coding of Electrical and Synaptic Input Actions by Nucl. Abducens Motoneurons with Active Dendrites: A Simulation Study by Kоrogod, S. М., Kulagina, I. B., Kukoushka, V. I.

“…The study was carried out on models of nucl. abducens motoneurons with dendritic arborizations reconstructed with a high spatial resolution. The arborizations…”
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Remote Modulation of Current Transfer from Dendritic Glutamatergic Synapses by GABA-ergic Synapses of the Somatic Zone of Motoneurons: a Simulation Study by Kulagina, I. B., Myakoushko, V. A., Korogod, S. M.

“…Until now, information concerning spatial interaction of postsynaptic excitation and inhibition in neuronal dendrites remains rather limited. In model…”
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