Search Results - "Kornisiuk, Edgar"
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Hippocampal NMDA receptors and the previous experience effect on memory
Published in Journal of physiology, Paris (01-09-2014)“…[Display omitted] •Previous OF sessions prevent IA amnesia caused by hippocampal NMDAR or MAChR blockade.•This “previous experience effect” would require some…”
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Amnesia of inhibitory avoidance by scopolamine is overcome by previous open-field exposure
Published in Learning & memory (Cold Spring Harbor, N.Y.) (01-11-2014)“…The muscarinic cholinergic receptor (MAChR) blockade with scopolamine either extended or restricted to the hippocampus, before or after training in inhibitory…”
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Muscarinic Inhibition of Hippocampal and Striatal Adenylyl Cyclase is Mainly Due to the M4 Receptor
Published in Neurochemical research (01-08-2009)“…The five muscarinic acetylcholine receptors (M 1 –M 5 ) are differentially expressed in the brain. M 2 and M 4 are coupled to inhibition of stimulated adenylyl…”
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Cholinergic neurotransmission and synaptic plasticity concerning memory processing
Published in Neurochemical research (01-04-1997)“…The brain is able to change the synaptic strength in response to stimuli that leave a memory trace. Long-term potentiation (LTP) and long-term depression (LTD)…”
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GluN1 and GluN2A NMDA Receptor Subunits Increase in the Hippocampus during Memory Consolidation in the Rat
Published in Frontiers in behavioral neuroscience (13-01-2017)“…It is widely accepted that NMDA receptors (NMDAR) are required for learning and memory formation, and for synaptic plasticity induction. We have previously…”
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Amnesia of Inhibitory Avoidance by Scopolamine Is Overcome by Previous Openfield Exposure
Published in Learning & memory (Cold Spring Harbor, N.Y.) (01-11-2014)“…The muscarinic cholinergic receptor (MAChR) blockade with scopolamine either extended or restricted to the hippocampus, before or after training in inhibitory…”
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A novel dihydro-pyrazolo(3,4d)(1,2,4)triazolo(1,5a)pyrimidin-4-one (AJ23) is an antagonist at adenosine A1 receptors and enhances consolidation of step-down avoidance
Published in Behavioural brain research (01-10-2012)“…► AJ23 is a non-xanthine compound with micromolar affinity at adenosine A1 receptors. ► AJ23 has little affinity at non-purine receptors for other neuroactive…”
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A novel dihydro-pyrazolo(3,4d)(1,2,4)triazolo(1,5a)pyrimidin-4-one (AJ23) is an antagonist at adenosine A(1) receptors and enhances consolidation of step-down avoidance
Published in Behavioural brain research (01-10-2012)“…Adenosine A(1) receptor antagonists are of potential value in the treatment of cognitive dysfunction. We have developed compound AJ23…”
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Memory impairment in rats by hippocampal administration of the serine protease subtilisin
Published in Behavioural brain research (16-05-2011)“…▶ Subtilisin (100ng) was injected into the hippocampus to assess effects on learning. ▶ In a step-through inhibitory avoidance of a mild footshock subtilisin…”
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M 4 muscarinic receptors are involved in modulation of neurotransmission at synapses of Schaffer collaterals on CA1 hippocampal neurons in rats
Published in Journal of neuroscience research (15-02-2009)“…All five subtypes of muscarinic acetylcholine receptors (mAChR; M 1 –M 5 ) are expressed in the hippocampus, where they are involved both in cognitive…”
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M4 muscarinic receptors are involved in modulation of neurotransmission at synapses of Schaffer collaterals on CA1 hippocampal neurons in rats
Published in Journal of neuroscience research (15-02-2009)“…All five subtypes of muscarinic acetylcholine receptors (mAChR; M1–M5) are expressed in the hippocampus, where they are involved both in cognitive functions…”
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Muscarinic Inhibition of Hippocampal and Striatal Adenylyl Cyclase is Mainly Due to the M sub(4) Receptor
Published in Neurochemical research (01-08-2009)“…The five muscarinic acetylcholine receptors (M sub(1)-M sub(5)) are differentially expressed in the brain. M sub(2) and M sub(4) are coupled to inhibition of…”
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Role of hippocampal M1 and M4 muscarinic receptor subtypes in memory consolidation in the rat
Published in Pharmacology, biochemistry and behavior (2003)“…Muscarinic receptors in the hippocampus are relevant to learning and memory, but the role of each subtype is poorly understood. Muscarinic toxins (MTs) from…”
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Facilitatory effect of the intra-hippocampal pre-test administration of MT3 in the inhibitory avoidance task
Published in Behavioural brain research (27-02-2007)“…The cholinergic system plays a crucial role in learning and memory. Modulatory mechanisms of this system in the acquisition and consolidation processes have…”
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Role of hippocampal M 1 and M 4 muscarinic receptor subtypes in memory consolidation in the rat
Published in Pharmacology, biochemistry and behavior (2003)“…Muscarinic receptors in the hippocampus are relevant to learning and memory, but the role of each subtype is poorly understood. Muscarinic toxins (MTs) from…”
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Effects of muscarinic toxins MT1 and MT2 from green mamba on different muscarinic cholinoceptors
Published in Neurochemical research (01-11-2002)“…MT1 and MT2, polypeptides from green mamba venom, known to bind to muscarinic cholinoceptors, behave like muscarinic agonists in an inhibitory avoidance task…”
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Muscarinic inhibition of hippocampal and striatal adenylyl cyclase is mainly due to the M(4) receptor
Published in Neurochemical research (01-08-2009)“…The five muscarinic acetylcholine receptors (M(1)-M(5)) are differentially expressed in the brain. M(2) and M(4) are coupled to inhibition of stimulated…”
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Binding of muscarinic toxins MT×1 and MT×2 from the venom of the green mamba Dendroaspis angusticeps to cloned human muscarinic cholinoceptors
Published in Toxicon (Oxford) (1995)“…Muscarinic toxins MTx1 and MTx2 are 7500 mol. wt polypeptides isolated from the venom of the green mamba snake Dendroaspis angusticeps. Previous competition…”
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Muscarinic toxin selective for m4 receptors impairs memory in the rat
Published in Neuroreport (11-05-1998)“…THE selectivity of the muscarinic toxin MT3 from green mamba snake venom was corroborated by inhibition of the binding of [H]NMS, a classical muscarinic…”
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Muscarinic toxins from the venom of Dendroaspis snakes with agonist-like actions
Published in Toxicon (Oxford) (01-04-1995)“…The venom of some Dendroaspis snakes contains small proteins (7500 mol. wt) that inhibit the binding of radiolabelled muscarinic antagonist to brain synaptomal…”
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