Search Results - "Kornilayev, Boris"
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Protein interactions with subcutaneously implanted biosensors
Published in Biomaterials (01-04-2006)“…Biofouling of in vivo glucose sensors has been indicated as the primary reason for sensitivity losses observed during the first 24 h after implant [Wisniewski…”
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Development and optimization of a useful assay for determining Hsp90’s inherent ATPase activity
Published in Bioorganic & medicinal chemistry (15-02-2006)“…The Hsp90 molecular chaperone is responsible for the conformational maturation of nascent polypeptides and the rematuration of denatured proteins. Inhibition…”
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QUANTITATIVE ANALYSIS OF CYTOCHROME P450 ISOZYMES BY MEANS OF UNIQUE ISOZYME-SPECIFIC TRYPTIC PEPTIDES: A PROTEOMIC APPROACH
Published in Drug metabolism and disposition (01-09-2005)“…A novel matrix-assisted laser desorption/ionization-time of flight (MALDI-TOF) mass spectrometry method has been developed to quantitate cytochrome P450 (P450)…”
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High-throughput screening for Hsp90 ATPase inhibitors
Published in Bioorganic & medicinal chemistry letters (01-06-2006)“…Recently, we reported a useful assay for the determination of Hsp90 ATPase activity. Using this assay, high-throughput screening of ∼10,000 compounds was…”
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Utility of polyclonal antibodies targeted toward unique tryptic peptides in the proteomic analysis of cytochrome P450 isozymes
Published in Toxicology in vitro (01-04-2008)“…P450s are key enzymes responsible for biotransformation of numerous endogenous and exogenous compounds and are located in almost every tissue. This superfamily…”
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Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry-based amino acid analysis
Published in Analytical biochemistry (15-12-2004)“…Amino acid analysis has been an integral part of analytical biochemistry for more than 50 years. However, its experimental design, which includes…”
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Identifying protein stabilizing ligands using GroEL
Published in Biopolymers (01-03-2010)“…Over the past 5 years, it has become increasingly apparent to researchers that the initial promise and excitement of using gene replacement therapies to…”
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Strategies for folding of affinity tagged proteins using GroEL and osmolytes
Published in Journal of structural and functional genomics (01-03-2009)“…Obtaining a proper fold of affinity tagged chimera proteins can be difficult. Frequently, the protein of interest aggregates after the chimeric affinity tag is…”
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