Search Results - "Kornhuber, J."

Individual differences in inflammatory and oxidative mechanisms of stress-related mood disorders by Kalinichenko, L.S., Kornhuber, J., Müller, C.P.

“…•Stress as a risk factor of mental illnesses, particularly depression.•Coping style as a predictor of stress resilience.•Inflammatory and oxidative mechanisms…”
Get full text

BOLD fMRI deactivation of limbic and temporal brain structures and mood enhancing effect by transcutaneous vagus nerve stimulation by Kraus, T, Hösl, K, Kiess, O, Schanze, A, Kornhuber, J, Forster, C

“…Direct vagus nerve stimulation (VNS) has proved to be an effective treatment for seizure disorder and major depression. However, since this invasive technique…”
Get full text

Therapeutic approaches to Alzheimer's disease by Klafki, Hans-Wolfgang, Staufenbiel, Matthias, Kornhuber, Johannes, Wiltfang, Jens

“…Alzheimer's disease is an age-related progressive neurodegenerative disorder with an enormous unmet medical need. It is the most common form of dementia…”
Get full text

Neurogranin and YKL-40: independent markers of synaptic degeneration and neuroinflammation in Alzheimer's disease by Hellwig, Konstantin, Kvartsberg, Hlin, Portelius, Erik, Andreasson, Ulf, Oberstein, Timo Jan, Lewczuk, Piotr, Blennow, Kaj, Kornhuber, Johannes, Maler, Juan Manuel, Zetterberg, Henrik, Spitzer, Philipp

“…Neuroinflammation and synaptic degeneration are major neuropathological hallmarks in Alzheimer's disease (AD). Neurogranin and YKL-40 in cerebrospinal fluid…”
Get full text

Antiviral and Anti-Inflammatory Activities of Fluoxetine in a SARS-CoV-2 Infection Mouse Model by Péricat, D., Leon-Icaza, S. A., Sánchez-Rico, M., Mühle, C., Zoicas, I., Schumacher, F., Planès, R., Mazars, R., Gros, G., Carpinteiro, A., Becker, K. A., Izopet, J., Strub-Wourgaft, N., Sjö, P., Neyrolles, O., Kleuser, B., Limosin, F., Gulbins, E., Kornhuber, J., Meunier, E., Hoertel, N., Cougoule, C.

“…Introduction The coronavirus disease 2019 (COVID-19) pandemic continues to cause significant morbidity and mortality worldwide. Since a large portion of the…”
Get full text

Antidepressant Use and Its Association with 28-Day Mortality in Inpatients with SARS-CoV-2: Support for the FIASMA Model against COVID-19 by Hoertel, N., Sanchez-Rico, M., Kornhuber, J., Gulbins, E., Reiersen, A., Lenze, E., Fritz, B. A., Jalali, F., Mills, E., Cougoule, C., Carpinteiro, A., Mühle, C., Becker-Flegler, K. A., Boulware, D. R., Blanco, C., Alvarado, J. M., Strub-Wourgaft, N., Lemogne, C., Limosin, F.

“…Introduction To reduce Coronavirus Disease 2019 (COVID-19)-related mortality and morbidity, widely available oral COVID-19 treatments are urgently needed…”
Get full text

Genome-wide significant risk factors for Alzheimer’s disease: role in progression to dementia due to Alzheimer's disease among subjects with mild cognitive impairment by Lacour, A, Espinosa, A, Louwersheimer, E, Heilmann, S, Hernández, I, Wolfsgruber, S, Fernández, V, Wagner, H, Rosende-Roca, M, Mauleón, A, Moreno-Grau, S, Vargas, L, Pijnenburg, Y A L, Koene, T, Rodríguez-Gómez, O, Ortega, G, Ruiz, S, Holstege, H, Sotolongo-Grau, O, Kornhuber, J, Peters, O, Frölich, L, Hüll, M, Rüther, E, Wiltfang, J, Scherer, M, Riedel-Heller, S, Alegret, M, Nöthen, M M, Scheltens, P, Wagner, M, Tárraga, L, Jessen, F, Boada, M, Maier, W, van der Flier, W M, Becker, T, Ramirez, A, Ruiz, A

“…Few data are available concerning the role of risk markers for Alzheimer’s disease (AD) in progression to AD dementia among subjects with mild cognitive…”
Get full text

Biomarker validation of a cued recall memory deficit in prodromal: Alzheimer disease by WAGNER, M, WOLF, S, HAMPEL, H, PERNECZKY, R, PETERS, O, JAHN, H, LUCKHAUS, C, GERTZ, H.-J, SCHRÖDER, J, PANTEL, J, LEWCZUK, P, KORNHUBER, J, REISCHIES, F. M, WILTFANG, J, DAERR, M, WOLFSGRUBER, S, JESSEN, F, POPP, J, MAIER, W, HÜLL, M, FRÖLICH, L

“…To compare cued recall measures with other memory and nonmemory tests regarding their association with a biomarker profile indicative of Alzheimer disease (AD)…”
Get full text

Soluble amyloid precursor proteins in the cerebrospinal fluid as novel potential biomarkers of Alzheimer's disease: a multicenter study by Lewczuk, P, Kamrowski-Kruck, H, Peters, O, Heuser, I, Jessen, F, Popp, J, Bürger, K, Hampel, H, Frölich, L, Wolf, S, Prinz, B, Jahn, H, Luckhaus, Ch, Perneczky, R, Hüll, M, Schröder, J, Kessler, H, Pantel, J, Gertz, H-J, Klafki, H-W, Kölsch, H, Reulbach, U, Esselmann, H, Maler, J M, Bibl, M, Kornhuber, J, Wiltfang, J

“…In this report, we present the results of a multicenter study to test analytic and diagnostic performance of soluble forms of amyloid precursor proteins α and…”
Get full text

Sphingolipids in psychiatric disorders and pain syndromes by Mühle, C, Reichel, M, Gulbins, E, Kornhuber, J

“…Despite the high prevalence and devastating impact of psychiatric disorders, little is known about their etiopathology. In this review, we provide an overview…”
Get more information

Prenatal and adult androgen activities in alcohol dependence by Lenz, B., Mühle, C., Braun, B., Weinland, C., Bouna‐Pyrrou, P., Behrens, J., Kubis, S., Mikolaiczik, K., Muschler, M.‐R., Saigali, S., Sibach, M., Tanovska, P., Huber, S. E., Hoppe, U., Eichler, A., Heinrich, H., Moll, G. H., Engel, A., Goecke, T. W., Beckmann, M. W., Fasching, P. A., Müller, C. P., Kornhuber, J.

“…Objective Alcohol dependence is more prevalent in men than in women. The evidence for how prenatal and adult androgens influence alcohol dependence is limited…”
Get full text

Excerpt from the history of the “Hochschulpsychiatrie Erlangen” (1818–2016): On the history of a connection between University and Institutional Psychiatry, Unique in Germany (1903–1974) by Braun, B, Kornhuber, J

“…Objective To examine the more than 70-year history of a connection between University and Institutional Psychiatry. Method Relevant archival material as well…”
Get full text

Characterization of the postsynaptic protein neurogranin in paired cerebrospinal fluid and plasma samples from Alzheimer's disease patients and healthy controls by Kvartsberg, Hlin, Portelius, Erik, Andreasson, Ulf, Brinkmalm, Gunnar, Hellwig, Konstantin, Lelental, Natalia, Kornhuber, Johannes, Hansson, Oskar, Minthon, Lennart, Spitzer, Philipp, Maler, Juan M, Zetterberg, Henrik, Blennow, Kaj, Lewczuk, Piotr

“…Synaptic dysfunction and degeneration are central events in Alzheimer's disease (AD) pathophysiology that are thought to occur early in disease progression…”
Get full text

Friedrich Georg Josef Meggendorfer (07.06.1880–12.02.1953) by Braun, B, Kornhuber, J

“…Introduction The DGPPN, as a German psychiatric professional society, demands a new, systematic viewing of the biographies, motivations, participations and…”
Get full text

Karl Leonhard (21.03.1904-23.04.1988) by Braun, B, Kornhuber, J

“…Introduction The procedure of meticulous description of the signs and symptoms of disease with ascription to localization applied was decisive to Leonhard's…”
Get full text

Epigenetic control of epilepsy target genes contributes to a cellular memory of epileptogenesis in cultured rat hippocampal neurons by Kiese, K, Jablonski, J, Hackenbracht, J, Wrosch, J K, Groemer, T W, Kornhuber, J, Blümcke, I, Kobow, K

“…Hypersynchronous neuronal excitation manifests clinically as seizure (ictogenesis), and may recur spontaneously and repetitively after a variable latency…”
Get full text

P.2.006 Prenatal testosterone activity determines adult alcohol drinking and morphology in mice by Huber, S, Lenz, B, Kornhuber, J, Müller, C

Get full text

Association between benzodiazepine receptor agonist use and mortality in patients hospitalised for COVID-19: a multicentre observational study by Hoertel, N., Sánchez-Rico, M., Gulbins, E., Kornhuber, J., Vernet, R., Beeker, N., Neuraz, A., Blanco, C., Olfson, M., Airagnes, G., Lemogne, C., Alvarado, J. M., Arnaout, M., Cougoule, C., Meneton, P., Limosin, F.

“…To examine the association between benzodiazepine receptor agonist (BZRA) use and mortality in patients hospitalised for coronavirus disease 2019 (COVID-19). A…”
Get full text

Association of Common Polymorphisms in the Nicotinic Acetylcholine Receptor Alpha4 Subunit Gene with an Electrophysiological Endophenotype in a Large Population-Based Sample by Mobascher, A, Diaz-Lacava, A, Wagner, M, Gallinat, J, Wienker, T F, Drichel, D, Becker, T, Steffens, M, Dahmen, N, Gründer, G, Thürauf, N, Kiefer, F, Kornhuber, J, Toliat, M R, Thiele, H, Nürnberg, P, Steinlein, O, Winterer, G

“…Variation in genes coding for nicotinic acetylcholine receptor (nAChR) subunits affect cognitive processes and may contribute to the genetic architecture of…”
Get full text

Lowered DNA methyltransferase (DNMT-3b) mRNA expression is associated with genomic DNA hypermethylation in patients with chronic alcoholism by Bönsch, D, Lenz, B, Fiszer, R, Frieling, H, Kornhuber, J, Bleich, S

“…DNA methyltransferases (DNMTs) are involved within the epigenetic control of DNA methylation processes. Recently, it has been shown that the genomic DNA…”
Get full text