Search Results - "Kornfilt, David"

Copper-Catalyzed Trifluoromethylation of Alkyl Bromides by Kornfilt, David J. P, MacMillan, David W. C

“…Copper oxidative addition into organohalides is a challenging two-electron process. In contrast, formal oxidative addition of copper to Csp2 carbon–bromine…”
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p97: An Emerging Target for Cancer, Neurodegenerative Diseases, and Viral Infections by Huryn, Donna M, Kornfilt, David J. P, Wipf, Peter

“…The AAA+ ATPase, p97, also referred to as VCP, plays an essential role in cellular homeostasis by regulating endoplasmic reticulum-associated degradation…”
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Catalytic, Enantioselective, Intramolecular Sulfenofunctionalization of Alkenes with Phenols by Denmark, Scott E, Kornfilt, David J. P

“…The catalytic, enantioselective, cyclization of phenols with electrophilic sulfenophthalimides onto isolated or conjugated alkenes affords 2,3-disubstituted…”
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Catalytic Asymmetric Thiofunctionalization of Unactivated Alkenes by Denmark, Scott E, Kornfilt, David J. P, Vogler, Thomas

“…Catalytic asymmetric sulfenylation of double bonds has been achieved using a BINAM-based phosphoramide catalyst and an electrophilic sulfur source. Simple…”
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Mechanistic, crystallographic, and computational studies on the catalytic, enantioselective sulfenofunctionalization of alkenes by Denmark, Scott E., Hartmann, Eduard, Kornfilt, David J. P., Wang, Hao

“…The stereocontrolled introduction of vicinal heteroatomic substituents into organic molecules is one of the most powerful ways of adding value and function…”
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Induction of G-quadruplex DNA structure by Zn(II) 5,10,15,20-tetrakis( N-methyl-4-pyridyl)porphyrin by Bhattacharjee, Amlan J., Ahluwalia, Karan, Taylor, Scott, Jin, Ou, Nicoludis, John M., Buscaglia, Robert, Brad Chaires, J., Kornfilt, David J.P., Marquardt, David G.S., Yatsunyk, Liliya A.

“…G-quadruplexes (GQ) are formed by the association of guanine-rich stretches of DNA. Certain small molecules can influence kinetics and thermodynamics of this…”
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Catalytic, Enantioselective Sulfenofunctionalisation of Alkenes: Mechanistic, Crystallographic, and Computational Studies by Denmark, Scott E., Hartmann, Eduard, Kornfilt, David J. P., Wang, Hao

“…The stereocontrolled introduction of vicinal heteroatomic substituents into organic molecules is one of the most powerful ways of adding value and function…”
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Abstract B037: Hit-finding by Cysteine-Scanning (HCS): A method for finding druggable pockets by van Tienen, Laurens Moore, Bayoumi, Shadwa, Muneeruddin, Khaja, Leymarie, Nancy, Kornfilt, David, Bian, Yuemin, Kesar, Devishi, Li, Ruitong, Atack, Thomas, Popa, Alexandra-Mariela, Jandova, Zuzana, Trollmann, Philipp, Bergner, Andreas, Rumpel, Klaus, Kessler, Dirk, Sellers, William R.

“…Large-scale cancer sequencing efforts coupled with deep functional genomic interrogation of cancer models provides us an increasingly detailed view of the…”
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Lewis Base Catalyzed Enantioselective Oxysulfenylation of Alkenes by Kornfilt, David Jean Pierre

“…The Lewis base activation of Lewis acids has been harnessed in the development of an enantioselective oxysulfenylation reaction for unactivated alkenes. The…”
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