Search Results - "Kornberg, Lori J."

Focal adhesion kinase and its potential involvement in tumor invasion and metastasis by Kornberg, Lori J.

“…Background Integrins are cell surface receptors which, in part, mediate the adhesion of cells to the extracelluar matrix. In addition to providing a molecular…”
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Expression of focal adhesion kinase and phosphorylated focal adhesion kinase in squamous cell carcinoma of the larynx by Aronsohn, Michael S., Brown, Heather M., Hauptman, Garrett, Kornberg, Lori J.

“…Objectives: Focal adhesion kinase (FAK) is overexpressed in a variety of human cancers including those derived from the oral cavity. The purpose of this work…”
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Adenoviruses increase endothelial cell proliferation, migration, and tube formation: Partial reversal by the focal adhesion kinase inhibitor, FRNK by Kornberg, Lori J., Grant, Maria B.

“…During the course of examining the feasibility of using an adenoviral vector to deliver a potential anti-angiogenic agent to endothelial cells, we discovered…”
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Adenovirus-mediated Transfer of FRNK Augments Drug-induced Cytotoxicity in Cultured SCCHN Cells by KORNBERG, Lori J

“…Background: Focal adhesion kinase (FAK), which is overexpressed in many human epithelial cancers, regulates cell cycle progression, cellular migration,…”
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Prevalence of genital psoriasis in patients with psoriasis by Meeuwis, Kim A. P., Potts Bleakman, Alison, van de Kerkhof, Peter C. M., Dutronc, Yves, Henneges, Carsten, Kornberg, Lori J., Menter, Alan

“…Background: Psoriatic lesions in the genital area (GenPs) can cause considerable physical and emotional distress. To increase physician awareness, we estimated…”
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Patient Characteristics, Health Care Resource Utilization, and Costs Associated with Treatment-Regimen Failure with Biologics in the Treatment of Psoriasis by Foster, Shonda A, Zhu, Baojin, Guo, Jiaying, Nikai, Enkeleida, Ojeh, Clement, Malatestinic, William, Goldblum, Orin, Kornberg, Lori J, Wu, Jashin J

“…Psoriasis is a chronic, incurable, and immune-mediated skin disorder that is characterized by erythematous scaly papules and plaques. Understanding of…”
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Hepatocyte growth factor/scatter factor stimulates mitogenesis and migration of a head and neck squamous cell carcinoma cell line by Fleigel, Jeffery, Sedwick, Jack, Kornberg, Lori J.

“…Objective: We sought to assess the effect of extracellular matrix and hepatocyte growth factor/scatter factor (HGF/SF) on the growth and motility of cultured…”
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Gene Expression Profiling in Squamous Cell Carcinoma of the Oral Cavity Shows Abnormalities in Several Signaling Pathways by Kornberg, Lori J., Villaret, Douglas, Popp, Michael, Lui, Li, McLaren, Rachel, Brown, Heather, Cohen, Donald, Yun, James, McFadden, Michael

“…Objectives/Hypothesis: To examine gene expression profiles in squamous cell carcinoma of the oral cavity (oral SCC) compared with histologically matched normal…”
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Phase II Study of Gemcitabine and Bevacizumab As First-Line Treatment in Taxane-Pretreated, HER2-Negative, Locally Recurrent or Metastatic Breast Cancer by Borson, Rachel, Harker, Graydon, Reeves, James, Beck, Thaddeus, Hager, Steven, Horvath, William, Jones, Michael, Tillinghast, Guy, Arrowsmith, Edward, Harrer, Grant, Kudrik, Fred J, Malamud, Stephen C, Bromund, Jane, Zeigler, Haoyue, Tai, Datchen Fritz, Kornberg, Lori J, Obasaju, Coleman, Orlando, Mauro, Yardley, Denise A

“…Micro-Abstract This single-arm phase II trial involving women with recurrent or metastatic breast cancer examined the efficacy and safety of adding bevacizumab…”
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Focal adhesion kinase expression in oral cancers by Kornberg, Lori J.

“…Background Evidence suggests that focal adhesion kinase (FAK) is involved in the pathogenesis of certain cancers. Focal adhesion kinase is overexpressed in…”
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Focal Adhesion Kinase Overexpression Induces Enhanced Pathological Retinal Angiogenesis by Kornberg, Lori J, Shaw, Lynn C, Spoerri, Polyxenie E, Caballero, Sergio, Grant, Maria B

“…Focal adhesion kinase (FAK) is involved in processes integral to angiogenesis, such as cell growth, survival, and migration. FAK is activated by angiogenic…”
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Two New Aromatic Constituents from the Rootwood of Aeschynomene mimosifolia by Fullas, Fekadu, Kornberg, Lori J, Wani, Mansukh C, Wall, Monroe E, Farnsworth, Norman R, Chagwedera, Tangai E, Kinghorn, A. Douglas

“…The rootwood of Aeschynomene mimosifolia Vatke (Leguminosae) has yielded a new neoflavonoid, mimosifoliol (1), and an unusual C16-styrylcycloheptenone…”
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Gene Expression Profiling in Squamous Cell Carcinoma of the Oral Cavity Shows Abnormalities in Several Signaling Pathways by Kornberg, Lori J., Villaret, Douglas, Popp, Michael, Lui, Li, McLaren, Rachel, Brown, Heather, Cohen, Donald, Yun, James, McFadden, Michael

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Signal Transduction by Integrins: Increased Protein Tyrosine Phosphorylation Caused by Clustering of β1Integrins by Kornberg, Lori J., Earp, H. Shelton, Turner, Christopher E., Prockop, Carol, Juliano, R. L.

“…The integrin family of cell adhesion receptors mediates many of the interactions between cells and the extracellular matrix. Because the extracellular matrix…”
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Overexpression of scatter factor and its receptor (c-met) in oral squamous cell carcinoma by Marshall, Darby D., Rornberg, Lori J.

“…Hypothesis: Scatter factor (SF) is a pleiotropic growth factor that recently has been shown to induce epithelial cell proliferation, random motility, and…”
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Nb2 cell mitogenesis: effect of lactogens on cAMP and protein phosphorylation by Kornberg, L J, Liberti, J P

“…Rat lymphoma cells (Nb2) are exquisitely sensitive to lactogenic hormones and are an ideal system to study receptor-mediated signal transduction. The effect of…”
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Lactogen-induced protein phosphorylation in Nb2 cells by Kornberg, L J, Liberti, J P

“…Lactogenic hormones are potent mitogenic agents in the Nb2 rat lymphoma cell line. Because selective phosphorylation/dephosphorylation of specific proteins by…”
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