Search Results - "Kornacker, M."

Regorafenib in combination with FOLFOX or FOLFIRI as first- or second-line treatment of colorectal cancer: results of a multicenter, phase Ib study by Schultheis, B., Folprecht, G., Kuhlmann, J., Ehrenberg, R., Hacker, U.T., Köhne, C.H., Kornacker, M., Boix, O., Lettieri, J., Krauss, J., Fischer, R., Hamann, S., Strumberg, D., Mross, K.B.

“…Metastatic colorectal cancer (mCRC) is commonly treated with 5-fluorouracil, folinic acid, and oxaliplatin or irinotecan. The multitargeted kinase inhibitor,…”
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Characteristics of relapse after autologous stem-cell transplantation for follicular lymphoma: a long-term follow-up by Kornacker, M., Stumm, J., Pott, C., Dietrich, S., Süssmilch, S., Hensel, M., Nickelsen, M., Witzens-Harig, M., Kneba, M., Schmitz, N., Ho, A. D., Dreger, P.

“…Background: Pattern and outcome of disease recurrence after autologous stem-cell transplantation (autoSCT) for follicular lymphoma (FL) is not well known…”
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IMPROVED OUTCOMES IN PATIENTS (PTS) WITH BCL2‐POSITIVE DIFFUSE LARGE B‐CELL LYMPHOMA (DLBCL) TREATED WITH VENETOCLAX (VEN) PLUS R‐CHOP: RESULTS FROM THE PHASE 2 CAVALLI STUDY by Morschhauser, F., Flinn, I.W., Gasiorowski, R., Illés, Á., Feugier, P., Greil, R., Johnson, N.A., Larouche, J., Lugtenburg, P.J., Patti, C., Salles, G., Trněný, M., Vos, S., Mir, F., Kornacker, M., Punnoose, E.A., Samineni, D., Szafer‐Glusman, E., Petrich, A., Sinha, A., Spielewoy, N., Humphrey, K., Bazeos, A., Zelenetz, A.D.

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Phase IB study of sorafenib in combination with gemcitabine and cisplatin in patients with refractory solid tumors by Schultheis, B., Kummer, G., Zeth, M., Brendel, E., Xia, C., Kornacker, M., Strumberg, D.

“…Purpose Sorafenib (BAY 43-9006), a multikinase inhibitor, has been shown to inhibit tumor growth and tumor angiogenesis by targeting Raf kinase, vascular…”
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Commercial LightCycler®-based quantitative real-time PCR compared to nested PCR for monitoring of Bcl-2/IgH rearrangement in patients with follicular lymphoma by Kornacker, M., Kornacker, B., Schmitt, C., Leo, E., Ho, A. D., Hensel, M.

“…Translocation of chromosomes 14 and 18 [t(14;18)] for detection of minimal residual disease in follicular lymphoma patients can be analyzed by nested…”
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The apoptotic and proliferative fate of cytokine-induced killer cells after redirection to tumor cells with bispecific Ab by Kornacker, M., Verneris, M.R., Kornacker, B., Ganten, T.M., Scheffold, C., Negrin, R.S.

“…Cytokine-induced killer (CIK) cells are ex vivo expanded T cells with co-expression of CD3 and CD56 and NK activity. They have recently been evaluated in a…”
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Gene activation by the AraC protein can be inhibited by DNA looping between AraC and a LexA repressor that interacts with AraC: possible applications as a two‐hybrid system by Kornacker, M. G., Remsburg, B., Menzel, R.

“…The Escherichia coli activator and repressor proteins AraC and LexA bind DNA as homodimers. Here we show that their heterodimerization through fused cognate…”
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Information essential for cell-cycle-dependent secretion of the 591-residue Caulobacter hook protein is confined to a 21-amino-acid sequence near the N-terminus by Kornacker, M G, Newton, A

“…Recent findings suggest that axial flagellar proteins and virulence proteins of Gram-negative bacteria are exported from the cytoplasm via conserved…”
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Thrombotic microangiopathy after combined autografting–allografting for multiple myeloma – report of three cases by Kornacker, M., Luft, T., Ho, A. D., Schaefer, H.‐J.

“…: Thrombotic microangiopathy (TMA) has been described as a complication of bone marrow or stem cell transplantation. It is usually associated with high dose…”
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1241 Mass balance study of the novel epothilone compound sagopilone in patients with advanced solid tumours by Focan, C, Kreutz, F, Moeneclaey, N, Lindemann, S, Reif, S, Wiesinger, H, Kornacker, M

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Escherichia coli One- and Two-Hybrid Systems for the Analysis and Identification of Protein–Protein Interactions by Hu, James C., Kornacker, Michael G., Hochschild, Ann

“…Genetic methods based on fusion proteins allow the power of a genetic approach to be applied to the self-assembly of proteins or protein fragments, regardless…”
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The normally periplasmic enzyme beta-lactamase is specifically and efficiently translocated through the Escherichia coli outer membrane when it is fused to the cell-surface enzyme pullulanase by Kornacker, M G, Pugsley, A P

“…Hybrid proteins were constructed in which C-terminal regions of the bacterial cell surface and extracellular protein pullulanase were replaced by the mature…”
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The general protein-export pathway is directly required for extracellular pullulanase secretion in Escherichia coli K12 by Pugsley, A P, Kornacker, M G, Poquet, I

“…Pullulanase is an extracellular, cell surface-anchored lipoprotein produced by Gram-negative bacteria belonging to the genus Klebsiella. Its correct…”
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1320MO Early evidence of efficacy in patients (pts) with non-small cell lung cancer (NSCLC) with HER2 exon20 insertion (ex20ins) mutations treated in a phase I study with BAY 2927088 by Loong, H.H.F., Daniele, G., Yang, T-Y., Leal, T.A., Goto, K., Shinno, Y., Nishino, K., Sakamoto, T., Felip, E., Ruffinelli, J.C., Gallot, N., Wang, Z., Chen, C., Brennan, B., Pu, S-F., Kornacker, M., Grassi, P., Le, X., Tan, D.S.W., Goh, B-C.

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48MO SQZ-PBMC-HPV-101: Preliminary results of a first-in-human, dose-escalation study of a cell-based vaccine in HLA A02+ patients with recurrent, locally advanced, or metastatic HPV16+ solid tumors by Park, J-C., Baranda, J.C., Mita, M.M., Iams, W.T., Gordon, M.S., Taylor, M., Dhani, N., Loughhead, S.M., Ji, R-R., Zwirtes, R.F., Kornacker, M., Rosen, O., Bernstein, H., Jimeno, A.

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Analysis of the subcellular location of pullulanase produced by Escherichia coli carrying the pulA gene from Klebsiella pneumoniae strain UNF5023 by Pugsley, A P, Kornacker, M G, Ryter, A

“…Three different techniques, protease accessibility, cell fractionation and in situ immunocytochemistry, were used to study the location of the lipoprotein…”
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Detection of identical Hodgkin-Reed Sternberg cell specific immunoglobulin gene rearrangements in a patient with Hodgkin's disease of mixed cellularity subtype at primary diagnosis and in relapse two and a half years later by Jox, A., Zander, T., Kornacker, M., Kanzler, H., Küppers, R., Diehl, V., Wolf, J.

“…Background: The malignant nature of Hodgkin-Reed Sternberg (H-RS) cells has been questioned due to their scarcity in lymphoma tissues. Recently, using…”
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Detection of a Hodgkin/Reed‐Sternberg cell specific immunoglobulin gene rearrangement in the serum DNA of a patient with Hodgkin's disease by Kornacker, M., Jox, A., Vockerodt, M., Tesch, H., Bohlen, H., Diehl, V., Wolf, J.

“…We analysed multiple serum samples from a patient with mixed cellularity Hodgkin's disease for the Hodgkin/Reed‐Sternberg cell clone‐specific rearranged Ig…”
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Loss of heterozygosity in the Hodgkin-Reed Sternberg cell line L1236 by STARATSCHEK-JOX, A, THOMAS, R. Kurt, ZANDER, T, MASSOUDI, N, KORNACKER, M, BULLERDIEK, J, FONATSCH, C, DIEHL, V, WOLF, J

“…Hodgkin-Reed Sternberg cells are derived from germinal centre B-cells in most cases. Somatic mutations affecting their rearranged immunoglobulin genes were…”
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Two distinct steps in pullulanase secretion by Escherichia coli K12 by Pugsley, A P, Poquet, I, Kornacker, M G

“…Two distinct steps in the secretion of the extracellular, cell-surface-anchored lipoprotein pullulanase by Escherichia coli were uncoupled by allowing export…”
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