Search Results - "Korman, L"
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Early Androgen Effects on Spatial and Mechanical Abilities: Evidence From Congenital Adrenal Hyperplasia
Published in Behavioral neuroscience (01-02-2012)“…There is considerable controversy about the origins of sex differences in cognitive abilities, particularly the male superiority in spatial abilities. We…”
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Interleukin 6 gene polymorphism is associated with protein serum level and disease activity in Polish patients with rheumatoid arthritis
Published in HLA : immune response genetics (01-12-2018)“…Interleukin 6 (IL‐6) is a pro‐inflammatory cytokine involved in the development of rheumatoid arthritis (RA). The present study aimed to determine the possible…”
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Capsule endoscopy structured terminology (CEST): proposal of a standardized and structured terminology for reporting capsule endoscopy procedures
Published in Endoscopy (01-10-2005)Get more information
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Tenfibgen ligand nanoencapsulation delivers bi-functional anti-CK2 RNAi oligomer to key sites for prostate cancer targeting using human xenograft tumors in mice
Published in PloS one (15-10-2014)“…Protected and specific delivery of nucleic acids to malignant cells remains a highly desirable approach for cancer therapy. Here we present data on the…”
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Mechanism and efficacy of sub-50-nm tenfibgen nanocapsules for cancer cell-directed delivery of anti-CK2 RNAi to primary and metastatic squamous cell carcinoma
Published in Molecular cancer therapeutics (01-08-2014)“…Improved survival for patients with head and neck cancers (HNC) with recurrent and metastatic disease warrants that cancer therapy is specific, with protected…”
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Antinuclear and antiphospholipid antibodies in patients with multiple sclerosis
Published in Lupus (01-04-2012)“…The prevalence of autoantibodies in multiple sclerosis (MS) patients and their clinical associations differ between various studies. This study investigated…”
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Site-directed spectroscopic probes of actomyosin structural dynamics
Published in Annual review of biophysics (01-01-2009)“…Spectroscopy of myosin and actin has entered a golden age. High-resolution crystal structures of isolated actin and myosin have been used to construct detailed…”
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Anthrax vaccine adsorbed: Further evidence supporting continuing the vaccination series rather than restarting the series when doses are delayed
Published in Vaccine (03-09-2014)“…Highlights • The anti-PA IgG antibody response and B. anthracis lethal toxin neutralization activity of a cohort delayed as long as 7 years in receiving an…”
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Structured terminology for capsule endoscopy: results of retrospective testing and validation in 766 small-bowel investigations
Published in Endoscopy (01-10-2005)“…Capsule endoscopy (CE) is an effective means of investigating the small bowel in patients with gastrointestinal diseases. Computerized reports are frequently…”
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Structural Dynamics of the Actin–Myosin Interface by Site-directed Spectroscopy
Published in Journal of molecular biology (10-03-2006)“…We have used site-directed spin and fluorescence labeling to test molecular models of the actin–myosin interface. Force is generated when the actin–myosin…”
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Phase I study of escalating doses of low-dose-rate, locoregional irradiation preceding Cytoxan-TBI for patients with chemotherapy-resistant non-Hodgkin's or Hodgkin's lymphoma
Published in International journal of radiation oncology, biology, physics (01-09-2003)“…In patients in whom bone marrow transplantation (BMT) fails, recurrence often occurs at sites known to have contained disease before initiating BMT. The…”
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Mutations in Actin Subdomain 3 That Impair Thin Filament Regulation by Troponin and Tropomyosin
Published in The Journal of biological chemistry (06-08-1999)“…Thin filament-mediated regulation of striated muscle contraction involves conformational switching among a few quaternary structures, with transitions induced…”
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Nanoencapsulated anti-CK2 small molecule drug or siRNA specifically targets malignant cancer but not benign cells
Published in Cancer letters (01-02-2012)“…Abstract CK2, a pleiotropic Ser/Thr kinase, is an important target for cancer therapy. We tested our novel tenfibgen-based nanocapsule for delivery of the…”
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Abstract 3746: A high dose priming strategy with the novel RNAi therapeutic GS-10 elevates RISC Ago2, Ago4 and GW182 protein levels to enhance RNAi efficacy in a metastatic solid tumor model
Published in Cancer research (Chicago, Ill.) (15-07-2016)“…Abstract A high initial priming dose of the novel RNAi therapeutic GS-10 was investigated as a strategy to elevate important RISC complex proteins that have…”
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CK2 targeted RNAi therapeutic delivered via malignant cell-directed tenfibgen nanocapsule: dose and molecular mechanisms of response in xenograft prostate tumors
Published in Oncotarget (20-09-2016)“…CK2, a protein serine/threonine kinase, promotes cell proliferation and suppresses cell death. This essential-for-survival signal demonstrates elevated…”
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An Actin Subdomain 2 Mutation That Impairs Thin Filament Regulation by Troponin and Tropomyosin
Published in The Journal of biological chemistry (21-07-2000)“…Striated muscle thin filaments adopt different quaternary structures, depending upon calcium binding to troponin and myosin binding to actin. Modification of…”
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Systemic administration of antisense oligonucleotides simultaneously targeting CK2α and α′ subunits reduces orthotopic xenograft prostate tumors in mice
Published in Molecular and cellular biochemistry (01-10-2011)“…CK2 is a highly conserved, ubiquitous, signal responsive protein serine/threonine kinase. CK2 promotes cell proliferation and suppresses apoptosis, and…”
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Digital imaging in endoscopy
Published in Gastrointestinal endoscopy (01-09-1998)Get full text
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Structured reporting in gastrointestinal endoscopy:: Integration with DICOM and minimal standard terminology
Published in International journal of medical informatics (01-02-1998)“…The interest of the international gastrointestinal endoscopy community in developing standards for endoscopic reporting resulted in a standard lexicon for…”
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Dialectical behavior therapy and the treatment of emotion dysregulation
Published in Journal of clinical psychology (01-02-2001)“…Borderline personality disorder (BPD) is a disorder characterized by severe disturbances in emotion regulation. In Dialectical Behavior Therapy (DBT), affect…”
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