Search Results - "Korkmaz, Funda"

Fabrication of doxycycline-loaded electrospun PCL/PEO membranes for a potential drug delivery system by Eskitoros-Togay, Ş. Melda, Bulbul, Y. Emre, Tort, Serdar, Demirtaş Korkmaz, Funda, Acartürk, Füsun, Dilsiz, Nursel

“…[Display omitted] •Doxycycline-loaded membranes are successfully fabricated by electrospinning method.•Hydrophobic and hydrophilic polymers are blended for the…”
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FDI-6 inhibits VEGF-B expression in metastatic breast cancer: a combined in vitro and in silico study by Duzgun, Zekeriya, Korkmaz, Funda Demirtaş, Akgün, Egemen

“…Angiogenesis is the process by which new blood vessels are formed to meet the oxygen and nutrient needs of tissues. This process is vitally important in many…”
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Effects of thiostrepton alone or in combination with selumetinib on triple-negative breast cancer metastasis by Demirtas Korkmaz, Funda, Dogan Turacli, Irem, Esendagli, Guldal, Ekmekci, Abdullah

“…Objective FoxM1 transcription factor contributes to tumor metastasis and poor prognosis in many cancers including triple-negative breast cancer (TNBC). In this…”
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Flavopiridol's effects on metastasis in KRAS mutant lung adenocarcinoma cells by Dogan Turacli, Irem, Demirtas Korkmaz, Funda, Candar, Tuba, Ekmekci, Abdullah

“…Background There is still no clinically approved agent for mutant KRAS, which is the most common alteration in non–small‐cell lung cancer (NSCLC). Flavopiridol…”
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Bone circuitry and interorgan skeletal crosstalk by Zaidi, Mone, Kim, Se-Min, Mathew, Mehr, Korkmaz, Funda, Sultana, Farhath, Miyashita, Sari, Gumerova, Anisa Azatovna, Frolinger, Tal, Moldavski, Ofer, Barak, Orly, Pallapati, Anusha, Rojekar, Satish, Caminis, John, Ginzburg, Yelena, Ryu, Vitaly, Davies, Terry F, Lizneva, Daria, Rosen, Clifford J, Yuen, Tony

“…The past decade has seen significant advances in our understanding of skeletal homeostasis and the mechanisms that mediate the loss of bone integrity in…”
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Memantine shifts cancer cell metabolism via AMPK1/2 mediated energetic switch in A549 lung cancer cells by Albayrak, Gulsah, Demirtas Korkmaz, Funda

“…Memantine is used to prevent glutamate-mediated excitotoxicity and neurodegeneration in Alzheimer's disease. As glutamine is one of the major source of…”
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An atlas of brain-bone sympathetic neural circuits in mice by Ryu, Vitaly, Gumerova, Anisa Azatovna, Witztum, Ronit, Korkmaz, Funda, Cullen, Liam, Kannangara, Hasni, Moldavski, Ofer, Barak, Orly, Lizneva, Daria, Goosens, Ki A, Stanley, Sarah, Kim, Se-Min, Yuen, Tony, Zaidi, Mone

“…There is clear evidence that the sympathetic nervous system (SNS) mediates bone metabolism. Histological studies show abundant SNS innervation of the…”
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THIOSTREPTON MODULATES TLR4 EXPRESSION AND INDUCES APOPTOSIS IN MDA MB 231 CELLS: AN IN VITRO AND IN SILICO ANALYSIS by Demırtaş Korkmaz, Funda, Düzgün, Zekeriya, Deveci Özkan, Asuman

“…Objective: Toll-like receptors (TLRs) are key pattern recognition receptors involved in tumorigenesis, apoptosis, and metastasis. Triple-negative breast cancer…”
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Development and biophysical characterization of a humanized FSH-blocking monoclonal antibody therapeutic formulated at an ultra-high concentration by Rojekar, Satish, Pallapati, Anusha R, Gimenez-Roig, Judit, Korkmaz, Funda, Sultana, Farhath, Sant, Damini, Haeck, Clement M, Macdonald, Anne, Kim, Se-Min, Rosen, Clifford J, Barak, Orly, Meseck, Marcia, Caminis, John, Lizneva, Daria, Yuen, Tony, Zaidi, Mone

“…Highly concentrated antibody formulations are oftentimes required for subcutaneous, self-administered biologics. Here, we report the development of a unique…”
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Antitumorigenic Effect of Memantine via Interfering Glutamate Metabolism in Mouse 4T1 Breast Tumor Model by Albayrak, Gulsah, Korkmaz, Funda D, Bali, Elif B, Bagriacik, Emin U

“…Repurposing drug is an efficient strategy as the drug discovery process is timeconsuming, laborious and costly. Memantine is already used in Alzheimer's…”
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Brain atlas for glycoprotein hormone receptors at single-transcript level by Ryu, Vitaly, Gumerova, Anisa, Korkmaz, Funda, Kang, Seong Su, Katsel, Pavel, Miyashita, Sari, Kannangara, Hasni, Cullen, Liam, Chan, Pokman, Kuo, TanChun, Padilla, Ashley, Sultana, Farhath, Wizman, Soleil A, Kramskiy, Natan, Zaidi, Samir, Kim, Se-Min, New, Maria I, Rosen, Clifford J, Goosens, Ki A, Frolinger, Tal, Haroutunian, Vahram, Ye, Keqiang, Lizneva, Daria, Davies, Terry F, Yuen, Tony, Zaidi, Mone

“…There is increasing evidence that anterior pituitary hormones, traditionally thought to have unitary functions in regulating single endocrine targets, act on…”
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Musculoskeletal and neurocognitive clinical significance of adult hypophosphatasia by Kim, Se-Min, Korkmaz, Funda, Sims, Steve, Ryu, Vitaly, Yuen, Tony, Zaidi, Mone

“…Hypophosphatasia (HPP), also called Rathbun disease, is a rare genetic disorder that is caused by the loss-of-function mutation in the gene encoding tissue…”
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Independent Skeletal Actions of Pituitary Hormones by Kim, Se-Min, Sultana, Farhath, Korkmaz, Funda, Lizneva, Daria, Yuen, Tony, Zaidi, Mone

“…Over the past years, pituitary hormones and their receptors have been shown to have non-traditional actions that allow them to bypass the…”
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FSH-blocking therapeutic for osteoporosis by Gera, Sakshi, Kuo, Tan-Chun, Gumerova, Anisa Azatovna, Korkmaz, Funda, Sant, Damini, DeMambro, Victoria, Sudha, Karthyayani, Padilla, Ashley, Prevot, Geoffrey, Munitz, Jazz, Teunissen, Abraham, van Leent, Mandy M T, Post, Tomas G J M, Fernandes, Jessica C, Netto, Jessica, Sultana, Farhath, Shelly, Eleanor, Rojekar, Satish, Kumar, Pushkar, Cullen, Liam, Chatterjee, Jiya, Pallapati, Anusha, Miyashita, Sari, Kannangara, Hasni, Bhongade, Megha, Sengupta, Puja, Ievleva, Kseniia, Muradova, Valeriia, Batista, Rogerio, Robinson, Cemre, Macdonald, Anne, Hutchison, Susan, Saxena, Mansi, Meseck, Marcia, Caminis, John, Iqbal, Jameel, New, Maria I, Ryu, Vitaly, Kim, Se-Min, Cao, Jay J, Zaidi, Neeha, Fayad, Zahi A, Lizneva, Daria, Rosen, Clifford J, Yuen, Tony, Zaidi, Mone

“…Pharmacological and genetic studies over the past decade have established the follicle-stimulating hormone (FSH) as an actionable target for diseases affecting…”
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Genotoxicity of Two Nanoparticles: Titanium Dioxide and Zinc Oxide by ÜNAL, Fatma, DEMIRTAŞ KORKMAZ, Funda, SULUDERE, Zekiye, EROL, Özlem, YÜZBAŞIOĞLU, Deniz

“…Nanoparticles (NPs) and nanoparticle-based materials have been increasingly used in various consumer and medical applications. However, investigations have…”
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The outcomes of an impaired powerhouse in KRAS mutant lung adenocarcinoma cells by Elesclomol by Albayrak, Gulsah, Korkmaz, Funda Demirtas, Tozcu, Duygu, Dogan Turacli, Irem

“…Objectives Lung cancer stands out as the most common cancer type worldwide. The most common genetic alteration detected in adenocarcinoma patients is KRAS…”
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Does memantine show chemopreventive effect against mice 4T1 breast tumor model? by Albayrak, Gülşah, Bali, Elif Burcu, Korkmaz, Funda Demirtaş, Bağrıaçık, Emin Ümit

“…Cancer cells express higher levels of N-methyl-d-aspartate (NMDA) receptor. In this study, we aimed to use memantine as a potential blocker to inhibit the…”
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Development of PCL/PEO electrospun fibrous membranes blended with silane-modified halloysite nanotube as a curcumin release system by Bulbul, Y. Emre, Okur, Mujgan, Demirtas-Korkmaz, Funda, Dilsiz, Nursel

“…In this work, electrospun fibrous membranes based on the polycaprolactone (PCL)/polyethylene oxide (PEO) blended with pure, 3-Aminopropyltriethoxysilane…”
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FSH blockade improves cognition in mice with Alzheimer’s disease by Xiong, Jing, Kang, Seong Su, Wang, Zhihao, Liu, Xia, Kuo, Tan-Chun, Korkmaz, Funda, Padilla, Ashley, Miyashita, Sari, Chan, Pokman, Zhang, Zhaohui, Katsel, Pavel, Burgess, Jocoll, Gumerova, Anisa, Ievleva, Kseniia, Sant, Damini, Yu, Shan-Ping, Muradova, Valeriia, Frolinger, Tal, Lizneva, Daria, Iqbal, Jameel, Goosens, Ki A., Gera, Sakshi, Rosen, Clifford J., Haroutunian, Vahram, Ryu, Vitaly, Yuen, Tony, Zaidi, Mone, Ye, Keqiang

“…Alzheimer’s disease has a higher incidence in older women, with a spike in cognitive decline that tracks with visceral adiposity, dysregulated energy…”
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Multi-walled carbon nanotube-incorporating electrospun composite fibrous mats for controlled drug release profile by Bulbul, Y. Emre, Eskitoros-Togay, Ş. Melda, Demirtas-Korkmaz, Funda, Dilsiz, Nursel

“…[Display omitted] The fabrication of electrospun composite nanofiber mats used as drug delivery systems with controlled release property is of general interest…”
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