Search Results - "Korf, H. ‐W."

Spinocerebellar ataxia type 1 (SCA1): new pathoanatomical and clinico-pathological insights by Rüb, U., Bürk, K., Timmann, D., den Dunnen, W., Seidel, K., Farrag, K., Brunt, E., Heinsen, H., Egensperger, R., Bornemann, A., Schwarzacher, S., Korf, H.-W., Schöls, L., Bohl, J., Deller, T.

“…U. Rüb, K. Bürk, D. Timmann, W. den Dunnen, K. Seidel, K. Farrag, E. Brunt, H. Heinsen, R. Egensperger, A. Bornemann, S. Schwarzacher, H.‐W. Korf, L. Schöls,…”
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Melatonin: A Clock-Output, A Clock-Input by Stehle, J. H., Von Gall, C., Korf, H.-W.

“…In mammals, the circadian system is comprised of three major components: the lateral eyes, the hypothalamic suprachiasmatic nucleus (SCN) and the pineal gland…”
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Huntington's disease (HD): the neuropathology of a multisystem neurodegenerative disorder of the human brain by Rüb, U., Seidel, K., Heinsen, H., Vonsattel, J.P., den Dunnen, W.F., Korf, H.W.

“…Huntington's disease (HD) is an autosomal dominantly inherited, and currently untreatable, neuropsychiatric disorder. This progressive and ultimately fatal…”
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Photoperiodic Control of TSH-β Expression in the Mammalian Pars Tuberalis has Different Impacts on the Induction and Suppression of the Hypothalamo-Hypopysial Gonadal Axis by Yasuo, S., Yoshimura, T., Ebihara, S., Korf , H.-W.

“…Seasonal reproduction depends on photoperiod‐regulated activation or suppression of the gonadal axis. Recent studies in quail have identified long‐day induced…”
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Polyglutamine aggregation in Huntington's disease and spinocerebellar ataxia type 3: similar mechanisms in aggregate formation by Seidel, K., Siswanto, S., Fredrich, M., Bouzrou, M., Brunt, E. R., van Leeuwen, F. W., Kampinga, H. H., Korf, H. -W., Rüb, U., den Dunnen, W. F. A.

“…Aims Polyglutamine (polyQ) diseases are characterized by the expansion of a polymorphic glutamine sequence in disease‐specific proteins and exhibit aggregation…”
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Molecular cloning, localization and circadian expression of chicken melanopsin (Opn4): differential regulation of expression in pineal and retinal cell types by Chaurasia, S. S., Rollag, M. D., Jiang, G., Hayes, W. P., Haque, R., Natesan, A., Zatz, M., Tosini, G., Liu, C., Korf, H. W., Iuvone, P. M., Provencio, I.

“…The avian retina and pineal gland contain autonomous circadian oscillators and photo‐entrainment pathways, but the photopigment(s) that mediate entrainment…”
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Inhibition of microglial and astrocytic inflammatory responses by the immunosuppressant mycophenolate mofetil by Dehghani, F., Sayan, M., Conrad, A., Evers, J., Ghadban, C., Blaheta, R., Korf, H.-W., Hailer, N. P.

“…F. Dehghani, M. Sayan, A. Conrad, J. Evers, C. Ghadban, R. Blaheta, H.‐W. Korf and N. P. Hailer (2010) Neuropathology and Applied Neurobiology36, 598–611…”
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Klaus Unsicker: in honor of his seventieth birthday by Korf, H.-W.

“…Issue Title: TGF-ß in Aging and Disease…”
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Dynamics of core body temperature cycles in long-term measurements under real life conditions in women by Ekhart, D, Wicht, H, Kersken, T, Ackermann, H, Kaczmarczyk, M, Pretzsch, G, Alexander, H, Korf, H W

“…Studies under real life conditions become more and more relevant in chronobiological and chronomedical research. The present study aims to analyze one of the…”
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Pineal melatonin synthesis is altered in Period1 deficient mice by Christ, E, Pfeffer, M, Korf, H.W, von Gall, C

“…Abstract Melatonin is an important endocrine signal for darkness in mammals. Transcriptional activation of the arylalkylamine- N -acetyltransferase gene…”
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Prognostic implication of histopathological, immunohistochemical and clinical features of oligodendrogliomas : a study of 89 cases by DEHGHANI, F, SCHACHENMAYR, W, LAUN, A, KORF, H.-W

“…Histopathological, immunohistochemical and clinical parameters were correlated with survival in 89 cases of oligodendroglioma (65 patients with grade II and 24…”
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The bisphosphonate clodronate depletes microglial cells in excitotoxically injured organotypic hippocampal slice cultures by Kohl, A., Dehghani, F., Korf, H.-W., Hailer, N.P.

“…The bisphosphonate clodronate, clinically used in the treatment of osteoporosis, is known to deplete cells of the monocytic lineage. Using an in vitro model of…”
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Molecular Cellular Mechanisms of Peptide Regulation of Melatonin Synthesis in Pinealocyte Culture by Khavinson, V. Kh, Linkova, N. S., Kvetnoy, I. M., Kvetnaia, T. V., Polyakova, V. O., Korf, H.-W.

“…The effects of epithalone and vilone peptides on the synthesis of melatonin and factors involved in this process, arylalkylamine-N-acetyltransferase (AANAT)…”
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The circadian system and melatonin: lessons from rats and mice by Korf, H W, Von Gall, C, Stehle, J

“…The circadian system (CS) comprises three key components: (1) endogenous oscillators (clocks) generating a circadian rhythm; (2) input pathways entraining the…”
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Selective adrenergic/cyclic AMP-dependent switch-off of proteasomal proteolysis alone switches on neural signal transduction : An example from the pineal gland by SCHOMERUS, Christof, KORF, Horst-Werner, LAEDTKE, Elke, WELLER, Joan L, KLEIN, David C

“…The molecular processes underlying neural transmission are central issues in neurobiology. Here we describe a novel mechanism through which noradrenaline (NA)…”
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Activation of Arylalkylamine N-Acetyltransferase by Phorbol Esters in Bovine Pinealocytes Suggests a Novel Regulatory Pathway in Melatonin Synthesis by Schomerus, C., Laedtke, E., Korf, H.-W.

“…In all mammalian species investigated, noradrenaline activates a β‐adrenoceptor/cAMP/protein kinase A‐dependent mechanism to switch on arylalkylamine…”
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Clock Gene Protein mPER1 is Rhythmically Synthesized and Under cAMP Control in the Mouse Pineal Organ by Von Gall, C., Schneider-Hüther, I., Pfeffer, M., Dehghani, F., Korf, H.-W., Stehle, J. H.

“…The mammalian clock gene Per1 is an important element of endogenous oscillators that control daily rhythms in central and peripheral tissues. Although such…”
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Calcium responses of isolated, immunocytochemically identified rat pinealocytes to noradrenergic, cholinergic and vasopressinergic stimulations by Schomerus, C., Laedtke, E., Korf, H.-W.

“…Calcium responses of isolated rat pineal cells to noradrenergic, cholinergic and vasopressinergic stimulations were recorded by use of the fura-2 technique and…”
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Distribution of regulatory subunits of protein kinase A and A kinase anchor proteins (AKAP 95, 150) in rat pinealocytes by Koch, M, Korf, H-W

“…The rat pineal organ is an established model to study signal transduction cascades that are activated by norepinephrine (NE) and cause increases in cAMP levels…”
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The pituitary adenylate cyclase-activating polypeptide-induced phosphorylation of the transcription factor CREB (cAMP response element binding protein) in the rat suprachiasmatic nucleus is inhibited by melatonin by Kopp, Michael, Meissl, Hilmar, Korf, Horst-W

“…The mammalian hypothalamic suprachiasmatic nucleus (SCN) is an endogenous pacemaker generating circadian rhythms. SCN activity is synchronized with…”
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