Search Results - "Korf, H W"
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Spinocerebellar ataxia type 1 (SCA1): new pathoanatomical and clinico-pathological insights
Published in Neuropathology and applied neurobiology (01-12-2012)“…U. Rüb, K. Bürk, D. Timmann, W. den Dunnen, K. Seidel, K. Farrag, E. Brunt, H. Heinsen, R. Egensperger, A. Bornemann, S. Schwarzacher, H.‐W. Korf, L. Schöls,…”
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Melatonin: A Clock-Output, A Clock-Input
Published in Journal of neuroendocrinology (01-04-2003)“…In mammals, the circadian system is comprised of three major components: the lateral eyes, the hypothalamic suprachiasmatic nucleus (SCN) and the pineal gland…”
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Huntington's disease (HD): the neuropathology of a multisystem neurodegenerative disorder of the human brain
Published in Brain pathology (Zurich, Switzerland) (01-11-2016)“…Huntington's disease (HD) is an autosomal dominantly inherited, and currently untreatable, neuropsychiatric disorder. This progressive and ultimately fatal…”
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Photoperiodic Control of TSH-β Expression in the Mammalian Pars Tuberalis has Different Impacts on the Induction and Suppression of the Hypothalamo-Hypopysial Gonadal Axis
Published in Journal of neuroendocrinology (01-01-2010)“…Seasonal reproduction depends on photoperiod‐regulated activation or suppression of the gonadal axis. Recent studies in quail have identified long‐day induced…”
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Polyglutamine aggregation in Huntington's disease and spinocerebellar ataxia type 3: similar mechanisms in aggregate formation
Published in Neuropathology and applied neurobiology (01-02-2016)“…Aims Polyglutamine (polyQ) diseases are characterized by the expansion of a polymorphic glutamine sequence in disease‐specific proteins and exhibit aggregation…”
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Molecular cloning, localization and circadian expression of chicken melanopsin (Opn4): differential regulation of expression in pineal and retinal cell types
Published in Journal of neurochemistry (01-01-2005)“…The avian retina and pineal gland contain autonomous circadian oscillators and photo‐entrainment pathways, but the photopigment(s) that mediate entrainment…”
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Inhibition of microglial and astrocytic inflammatory responses by the immunosuppressant mycophenolate mofetil
Published in Neuropathology and applied neurobiology (01-12-2010)“…F. Dehghani, M. Sayan, A. Conrad, J. Evers, C. Ghadban, R. Blaheta, H.‐W. Korf and N. P. Hailer (2010) Neuropathology and Applied Neurobiology36, 598–611…”
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Klaus Unsicker: in honor of his seventieth birthday
Published in Cell and tissue research (2012)“…Issue Title: TGF-ß in Aging and Disease…”
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Dynamics of core body temperature cycles in long-term measurements under real life conditions in women
Published in Chronobiology international (01-01-2018)“…Studies under real life conditions become more and more relevant in chronobiological and chronomedical research. The present study aims to analyze one of the…”
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Pineal melatonin synthesis is altered in Period1 deficient mice
Published in Neuroscience (01-12-2010)“…Abstract Melatonin is an important endocrine signal for darkness in mammals. Transcriptional activation of the arylalkylamine- N -acetyltransferase gene…”
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Prognostic implication of histopathological, immunohistochemical and clinical features of oligodendrogliomas : a study of 89 cases
Published in Acta neuropathologica (01-05-1998)“…Histopathological, immunohistochemical and clinical parameters were correlated with survival in 89 cases of oligodendroglioma (65 patients with grade II and 24…”
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The bisphosphonate clodronate depletes microglial cells in excitotoxically injured organotypic hippocampal slice cultures
Published in Experimental neurology (01-05-2003)“…The bisphosphonate clodronate, clinically used in the treatment of osteoporosis, is known to deplete cells of the monocytic lineage. Using an in vitro model of…”
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Molecular Cellular Mechanisms of Peptide Regulation of Melatonin Synthesis in Pinealocyte Culture
Published in Bulletin of experimental biology and medicine (01-06-2012)“…The effects of epithalone and vilone peptides on the synthesis of melatonin and factors involved in this process, arylalkylamine-N-acetyltransferase (AANAT)…”
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The circadian system and melatonin: lessons from rats and mice
Published in Chronobiology international (01-01-2003)“…The circadian system (CS) comprises three key components: (1) endogenous oscillators (clocks) generating a circadian rhythm; (2) input pathways entraining the…”
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Selective adrenergic/cyclic AMP-dependent switch-off of proteasomal proteolysis alone switches on neural signal transduction : An example from the pineal gland
Published in Journal of neurochemistry (01-11-2000)“…The molecular processes underlying neural transmission are central issues in neurobiology. Here we describe a novel mechanism through which noradrenaline (NA)…”
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Activation of Arylalkylamine N-Acetyltransferase by Phorbol Esters in Bovine Pinealocytes Suggests a Novel Regulatory Pathway in Melatonin Synthesis
Published in Journal of neuroendocrinology (01-09-2004)“…In all mammalian species investigated, noradrenaline activates a β‐adrenoceptor/cAMP/protein kinase A‐dependent mechanism to switch on arylalkylamine…”
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Clock Gene Protein mPER1 is Rhythmically Synthesized and Under cAMP Control in the Mouse Pineal Organ
Published in Journal of neuroendocrinology (01-04-2001)“…The mammalian clock gene Per1 is an important element of endogenous oscillators that control daily rhythms in central and peripheral tissues. Although such…”
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Calcium responses of isolated, immunocytochemically identified rat pinealocytes to noradrenergic, cholinergic and vasopressinergic stimulations
Published in Neurochemistry international (01-08-1995)“…Calcium responses of isolated rat pineal cells to noradrenergic, cholinergic and vasopressinergic stimulations were recorded by use of the fura-2 technique and…”
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Distribution of regulatory subunits of protein kinase A and A kinase anchor proteins (AKAP 95, 150) in rat pinealocytes
Published in Cell and tissue research (01-12-2002)“…The rat pineal organ is an established model to study signal transduction cascades that are activated by norepinephrine (NE) and cause increases in cAMP levels…”
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The pituitary adenylate cyclase-activating polypeptide-induced phosphorylation of the transcription factor CREB (cAMP response element binding protein) in the rat suprachiasmatic nucleus is inhibited by melatonin
Published in Neuroscience letters (23-05-1997)“…The mammalian hypothalamic suprachiasmatic nucleus (SCN) is an endogenous pacemaker generating circadian rhythms. SCN activity is synchronized with…”
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