Search Results - "Koretzky, G"

Frequency of hand contact with hospital surfaces in hospitalized pediatric patients by José F. Mier-de Leija, Daniela de la Rosa-Zamboni, Juan J. L. Sienra-Monge, Horacio Márquez-González, Solange G. Koretzky

“…Background: Hand hygiene (HH) is an important strategy for preventing health-care-associated infections (HAIs). Few programs focus on HH for family members and…”
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The Adapter Protein SLP-76 Mediates “Outside-In” Integrin Signaling and Function in T Cells by Baker, R. G., Hsu, C. J., Lee, D., Jordan, M. S., Maltzman, J. S., Hammer, D. A., Baumgart, T., Koretzky, G. A.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Transgénero en la edad pediátrica y riesgo cardiovascular by Solange G. Koretzky, Alfonso Buendía-Hernández

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Coupling of the TCR to Integrin Activation by SLAP-130/Fyb by Peterson, Erik J., Woods, Melody L., Dmowski, Sally A., Derimanov, Geo, Jordan, Martha S., Wu, Jennifer N., Myung, Peggy S., Liu, Qing-Hua, Pribila, Jonathan T., Freedman, Bruce D., Shimizu, Yoji, Koretzky, Gary A.

“…SLAP-130/Fyb (SLP-76-associated phosphoprotein or Fyn-binding protein; also known as Fyb/Slap) is a hematopoietic-specific adapter, which associates with and…”
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CpG motifs in bacterial DNA trigger direct B-cell activation by Krieg, Arthur M, Yi, Ae-Kyung, Matson, Sara, Waldschmidt, Thomas J, Bishop, Gail A, Teasdale, Rebecca, Koretzky, Gary A, Klinman, Dennis M

“…Unmethylated CpG dinucleotides are more frequent in the genomes of bacteria and viruses than of vertebrates. We report here that bacterial DNA and synthetic…”
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Requirement for the Leukocyte-Specific Adapter Protein SLP-76 for Normal T Cell Development by Clements, James L., Yang, Baoli, Ross-Barta, Susan E., Eliason, Steve L., Hrstka, Ronald F., Williamson, Roger A., Koretzky, Gary A.

“…The leukocyte-specific adapter molecule SLP-76 (Src homology 2 domain-containing leukocyte protein of 76 kilodaltons) is rapidly phosphorylated on tyrosine…”
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Tyrosine Phosphatase CD45 is Required for T-Cell Antigen Receptor and CD2- Mediated Activation of a Protein Tyrosine Kinase and Interleukin 2 Production by Koretzky, Gary A., Picus, Joel, Schultz, Terrie, Weiss, Arthur

“…CD45, a hematopoietic cell-specific surface antigen, has recently been shown to be a protein tyrosine phosphatase. Expression of CD45 is essential for the…”
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Regulation of NKT cell development by SAP, the protein defective in XLP by Nichols, Kim E, Stein, Paul L, Hom, Jamie, Gong, Shun-You, Ganguly, Arupa, Ma, Cindy S, Cannons, Jennifer L, Tangye, Stuart G, Schwartzberg, Pamela L, Koretzky, Gary A

“…The adaptor molecule SAP is expressed in T lymphocytes and natural killer (NK) cells, where it regulates cytokine production and cytotoxicity. Here, we show…”
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Adaptors as central mediators of signal transduction in immune cells by Koretzky, Gary A, Jordan, Martha S, Singer, Andrew L

“…Adaptors are molecular scaffolds that recruit effectors, which are critical for immune cell activation. Recent work has underscored the requirement for…”
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Coordination of receptor signaling in multiple hematopoietic cell lineages by the adaptor protein SLP-76 by Jordan, Martha S, Koretzky, Gary A

“…The adaptor protein SLP-76 is expressed in multiple hematopoietic lineages including T cells, platelets, and neutrophils. SLP-76 mediated signaling is…”
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Stimulatory effects of the protein tyrosine phosphatase inhibitor, pervanadate, on T-cell activation events by SECRIST, J. P, BURNS, L. A, KARNITZ, L, KORETZKY, G. A, ABRAHAM, R. T

“…Ligation of the multimeric T-cell antigen receptor complex (TCR) triggers a pleiotropic cellular activation response that includes lymphokine secretion,…”
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Regulation of Blood and Lymphatic Vascular Separation by Signaling Proteins SLP-76 and Syk by Abtahian, Farhad, Guerriero, Anastasia, Sebzda, Eric, Lu, Min-Min, Zhou, Rong, Mocsai, Attila, Myers, Erin E., Huang, Bin, Jackson, David G., Ferrari, Victor A., Tybulewicz, Victor, Lowell, Clifford A., Lepore, John J., Koretzky, Gary A., Kahn, Mark L.

“…Lymphatic vessels develop from specialized endothelial cells in preexisting blood vessels, but the molecular signals that regulate this separation are unknown…”
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Fas Ligation Induces Apoptosis and Jun Kinase Activation Independently of CD45 and Lck in Human T Cells by Latinis, Kevin M., Koretzky, Gary A.

“…Stimulation through the Fas/APO-1 receptor results in apoptosis through an incompletely characterized signaling pathway. More is known regarding signal…”
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Tyrosine phosphatase CD45 is essential for coupling T-cell antigen receptor to the phosphatidyl inositol pathway by Koretzky, Gary A, Picus, Joel, Thomas, Matthew L, Weiss, Arthur

“…Stimulation of T lymphocytes through their antigen receptor (T-cell receptor; TCR) results in the activation of a tyrosine kinase and the generation of…”
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Positive and negative regulation of t-cell activation by adaptor proteins by Koretzky, Gary A, Myung, Peggy S

“…Adaptor proteins, molecules that mediate intermolecular interactions, are now known to be as crucial for lymphocyte activation as are receptors and effectors…”
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The hematopoietic-specific adaptor protein Gads functions in T-cell signaling via interactions with the SLP-76 and LAT adaptors by Liu, Stanley K., Fang, Nan, Koretzky, Gary A., Jane McGlade, C.

“…Background: The adaptor protein Gads is a Grb2-related protein originally identified on the basis of its interaction with the tyrosine-phosphorylated form of…”
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Functional activation of the T-cell antigen receptor induces tyrosine phosphorylation of phospholipase C-gamma 1 by Weiss, A, Koretzky, G, Schatzman, R C, Kadlecek, T

“…Stimulation of the T-cell antigen receptor (TCR), which itself is not a protein-tyrosine kinase (PTK), activates a PTK and phospholipase C (PLC). Using the…”
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The SLP-76 family of adapter proteins by Wu, Jennifer N., Koretzky, Gary A.

“…Adapter molecules are multidomain proteins lacking intrinsic catalytic activity, functioning instead by nucleating molecular complexes during signal…”
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The future of the ASCI (American Society for Clinical Investigation) : a lesson from 2000 presidential election by Koretzky, G A

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Interaction of SLP adaptors with the SH2 domain of Tec family kinases by Su, Yu‐Wen, Zhang, Yong, Schweikert, Jutta, Koretzky, Gary A., Reth, Michael, Wienands, Jürgen

“…Activation of lymphocytes through their antigen receptors leads to mobilization of intracellular Ca2+ ions. This process requires expression of SLP adaptors…”
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