Search Results - "Korenč, Matevž"
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A novel allosteric mechanism in the cysteine peptidase cathepsin K discovered by computational methods
Published in Nature communications (11-02-2014)“…Allosteric modifiers have the potential to fine-tune enzyme activity. Therefore, targeting allosteric sites is gaining increasing recognition as a strategy in…”
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Human cathepsin L, a papain‐like collagenase without proline specificity
Published in The FEBS journal (01-11-2015)“…Several members of the papain‐like peptidase family have the ability to degrade collagen molecules by cleaving within the triple helix region of this difficult…”
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Scalable multimodal weak anion exchange chromatographic purification for stable mRNA drug substance
Published in Electrophoresis (01-12-2023)“…Messenger RNA (mRNA) has emerged as a modality with immense therapeutic potential. Recent innovations in production process of mRNA call for procedures to…”
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Gram‐Scale mRNA Production Using a 250‐mL Single‐Use Bioreactor
Published in Chemie ingenieur technik (01-12-2022)“…The COVID‐19 pandemic triggered an unprecedented surge in development of mRNA‐based vaccines. Despite the need to increase process productivity and thus…”
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