Simulating NEMA characteristics of the modular total-body J-PET scanner -- an economic total-body PET from plastic scintillators

Simulating NEMA characteristics of the modular total-body J-PET scanner -- an economic total-body PET from plastic scintillators

The purpose of the presented research is estimation of the performance characteristics of the economic Total-Body Jagiellonian-PET system (TB-J-PET) constructed from plastic scintillators. The characteristics are estimated according to the NEMA NU-2-2018 standards utilizing the GATE package. The sim...

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Main Authors: Moskal, Paweł, Kowalski, Paweł, Shopa, Roman, Raczyński, Lech, Baran, Jakub, Chug, Neha, Curceanu, Catalina, Czerwiński, Eryk, Dadgar, Meysam, Dulski, Kamil, Gajos, Aleksander, Hiesmayr, Beatrix, Kacprzak, Krzysztof, Kapłon, Łukasz, Kisielewska, Daria, Klimaszewski, Konrad, Kopka, Przemysław, Korcyl, Gregorz, Krawczyk, Nikodem, Krzemień, Wojciech, Kubicz, Ewelina, Niedźwiecki, Szymon, Parzych, Szymon, Raj, Juhi, Sharma, Sushil, Shivani, Shivani, Stȩpień, Ewa, Tayefi, Faranak, Wiślicki, Wojciech
Format: Journal Article
Language:English
Published: 03-07-2021
Subjects:
Physics - Instrumentation and Detectors
Physics - Medical Physics
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Summary:The purpose of the presented research is estimation of the performance characteristics of the economic Total-Body Jagiellonian-PET system (TB-J-PET) constructed from plastic scintillators. The characteristics are estimated according to the NEMA NU-2-2018 standards utilizing the GATE package. The simulated detector consists of 24 modules, each built out of 32 plastic scintillator strips (each with cross section of 6 mm times 30 mm and length of 140 cm or 200 cm) arranged in two layers in regular 24-sided polygon circumscribing a circle with the diameter of 78.6 cm. For the TB-J-PET with an axial field-of-view (AFOV) of 200 cm, a spatial resolutions of 3.7 mm (transversal) and 4.9 mm (axial) are achieved. The NECR peak of 630 kcps is expected at 30 kBq/cc activity concentration and the sensitivity at the center amounts to 38 cps/kBq. The SF is estimated to 36.2 %. The values of SF and spatial resolution are comparable to those obtained for the state-of-the-art clinical PET scanners and the first total-body tomographs: uExplorer and PennPET. With respect to the standard PET systems with AFOV in the range from 16 cm to 26 cm, the TB-J-PET is characterized by an increase in NECR approximately by factor of 4 and by the increase of the whole-body sensitivity by factor of 12.6 to 38. The TOF resolution for the TB-J-PET is expected to be at the level of CRT=240 ps (FWHM). For the TB-J-PET with an axial field-of-view (AFOV) of 140 cm, an image quality of the reconstructed images of a NEMA IEC phantom was presented with a contrast recovery coefficient (CRC) and a background variability parameters. The increase of the whole-body sensitivity and NECR estimated for the TB-J-PET with respect to current commercial PET systems makes the TB-J-PET a promising cost-effective solution for the broad clinical applications of total-body PET scanners.
DOI:10.48550/arxiv.2107.01356