Search Results - "Korcari, Antonion"
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Correction: Scleraxis-lineage cells are required for tendon homeostasis and their depletion induces an accelerated extracellular matrix aging phenotype
Published in eLife (03-01-2024)Get full text
Journal Article -
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Scleraxis-lineage cell depletion improves tendon healing and disrupts adult tendon homeostasis
Published in eLife (22-01-2021)“…Despite the requirement for -lineage (Scx ) cells during tendon development, the function of Scx cells during adult tendon repair, post-natal growth, and adult…”
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Journal Article -
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Scleraxis-lineage cells are required for tendon homeostasis and their depletion induces an accelerated extracellular matrix aging phenotype
Published in eLife (19-01-2023)“…Aged tendons have disrupted homeostasis, increased injury risk, and impaired healing capacity. Understanding mechanisms of homeostatic disruption is crucial…”
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Journal Article -
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Depletion of Scleraxis-lineage cells during tendon healing transiently impairs multi-scale restoration of tendon structure during early healing
Published in PloS one (14-10-2022)“…Tendons are composed of a heterogeneous cell environment, with Scleraxis-lineage (ScxLin) cells being the predominant population. Although ScxLin cells are…”
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Journal Article -
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Impact of aging on tendon homeostasis, tendinopathy development, and impaired healing
Published in Connective tissue research (02-01-2023)“…Aging is a complex and progressive process where the tissues of the body demonstrate a decreased ability to maintain homeostasis. During aging, there are…”
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Journal Article -
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Deciphering the Functions of Scleraxis-Lineage (ScxLin) Cells to Define Cellular and Molecular Programs Responsible for Tendon Homeostasis Maintenance and Regeneration after Injury
Published 01-01-2022“…During adulthood, tendon homeostasis is maintained via ongoing turnover of extracellular matrix (ECM) components. However, during aging, declines in tendon…”
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Dissertation -
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Characterization of scar tissue biomechanics during adult murine flexor tendon healing
Published in Journal of the mechanical behavior of biomedical materials (01-06-2022)“…Tendon injuries are very common and result in significant impairments in mobility and quality of life. During healing, tendons produce a scar at the injury…”
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Journal Article -
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Method development and characterization of chick embryo tendon mechanical properties
Published in Journal of biomechanics (01-03-2022)“…Tendons are involved in multiple disorders and injuries, ranging from birth deformities to tendinopathies to acute ruptures. The ability to characterize…”
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Journal Article -
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Increased Ca2+ signaling through CaV1.2 induces tendon hypertrophy with increased collagen fibrillogenesis and biomechanical properties
Published in The FASEB journal (01-07-2023)“…Tendons are tension‐bearing tissues transmitting force from muscle to bone for body movement. This mechanical loading is essential for tendon development,…”
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Journal Article -
10
Increased Ca2+ signaling through CaV 1.2 induces tendon hypertrophy with increased collagen fibrillogenesis and biomechanical properties
Published in The FASEB journal (01-07-2023)“…Tendons are tension-bearing tissues transmitting force from muscle to bone for body movement. This mechanical loading is essential for tendon development,…”
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Journal Article -
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Identification of Periostin as a critical niche for myofibroblast dynamics and fibrosis during tendon healing
Published in Matrix biology (01-01-2024)“…•Periostin-lineage cells contribute to a transient but not persistent myofibroblast population.•Periostin serves as a supportive niche for myofibroblast…”
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Journal Article -
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Increased Ca 2+ signaling through Ca V 1.2 induces tendon hypertrophy with increased collagen fibrillogenesis and biomechanical properties
Published in The FASEB journal (01-07-2023)“…Tendons are tension-bearing tissues transmitting force from muscle to bone for body movement. This mechanical loading is essential for tendon development,…”
Get full text
Journal Article -
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Cue-Signal-Response Analysis in 3D Chondrocyte Scaffolds with Anabolic Stimuli
Published in Annals of biomedical engineering (01-02-2018)“…Articular cartilage is an avascular connective tissue responsible for bearing loads. Cell signaling plays a central role in cartilage homeostasis and tissue…”
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Journal Article -
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Correction to: Cue-Signal-Response Analysis in 3D Chondrocyte Scaffolds with Anabolic Stimuli
Published in Annals of biomedical engineering (01-07-2019)“…This erratum is to add the following paragraph in the Acknowledgement section:…”
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Journal Article -
15
Depletion of Scleraxis-lineage cells during tendon healing transiently impairs multi-scale restoration of tendon structure during early healing
Published in PloS one (01-01-2022)“…Tendons are composed of a heterogeneous cell environment, with Scleraxis-lineage (ScxLin) cells being the predominant population. Although ScxLin cells are…”
Get full text
Journal Article