Search Results - "Korcari, Antonion"

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  1. 1
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    Scleraxis-lineage cell depletion improves tendon healing and disrupts adult tendon homeostasis by Best, Katherine T, Korcari, Antonion, Mora, Keshia E, Nichols, Anne Ec, Muscat, Samantha N, Knapp, Emma, Buckley, Mark R, Loiselle, Alayna E

    Published in eLife (22-01-2021)
    “…Despite the requirement for -lineage (Scx ) cells during tendon development, the function of Scx cells during adult tendon repair, post-natal growth, and adult…”
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    Journal Article
  3. 3

    Scleraxis-lineage cells are required for tendon homeostasis and their depletion induces an accelerated extracellular matrix aging phenotype by Korcari, Antonion, Nichols, Anne E C, Buckley, Mark R, Loiselle, Alayna E

    Published in eLife (19-01-2023)
    “…Aged tendons have disrupted homeostasis, increased injury risk, and impaired healing capacity. Understanding mechanisms of homeostatic disruption is crucial…”
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    Journal Article
  4. 4

    Depletion of Scleraxis-lineage cells during tendon healing transiently impairs multi-scale restoration of tendon structure during early healing by Korcari, Antonion, Muscat, Samantha, McGinn, Elizabeth, Buckley, Mark R, Loiselle, Alayna E

    Published in PloS one (14-10-2022)
    “…Tendons are composed of a heterogeneous cell environment, with Scleraxis-lineage (ScxLin) cells being the predominant population. Although ScxLin cells are…”
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    Journal Article
  5. 5

    Impact of aging on tendon homeostasis, tendinopathy development, and impaired healing by Korcari, Antonion, Przybelski, Samantha J, Gingery, Anne, Loiselle, Alayna E

    Published in Connective tissue research (02-01-2023)
    “…Aging is a complex and progressive process where the tissues of the body demonstrate a decreased ability to maintain homeostasis. During aging, there are…”
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    Journal Article
  6. 6

    Deciphering the Functions of Scleraxis-Lineage (ScxLin) Cells to Define Cellular and Molecular Programs Responsible for Tendon Homeostasis Maintenance and Regeneration after Injury by Korcari, Antonion

    Published 01-01-2022
    “…During adulthood, tendon homeostasis is maintained via ongoing turnover of extracellular matrix (ECM) components. However, during aging, declines in tendon…”
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    Dissertation
  7. 7

    Characterization of scar tissue biomechanics during adult murine flexor tendon healing by Korcari, Antonion, Buckley, Mark R., Loiselle, Alayna E.

    “…Tendon injuries are very common and result in significant impairments in mobility and quality of life. During healing, tendons produce a scar at the injury…”
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    Journal Article
  8. 8

    Method development and characterization of chick embryo tendon mechanical properties by Navarro, Javier, Korcari, Antonion, Nguyen, Phong, Bah, Ibrahima, AlKhalifa, Abdulrahman, Fink, Spencer, Buckley, Mark, Kuo, Catherine K.

    Published in Journal of biomechanics (01-03-2022)
    “…Tendons are involved in multiple disorders and injuries, ranging from birth deformities to tendinopathies to acute ruptures. The ability to characterize…”
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    Journal Article
  9. 9

    Increased Ca2+ signaling through CaV1.2 induces tendon hypertrophy with increased collagen fibrillogenesis and biomechanical properties by Li, Haiyin, Korcari, Antonion, Ciufo, David, Mendias, Christopher L., Rodeo, Scott A., Buckley, Mark R., Loiselle, Alayna E., Pitt, Geoffrey S., Cao, Chike

    Published in The FASEB journal (01-07-2023)
    “…Tendons are tension‐bearing tissues transmitting force from muscle to bone for body movement. This mechanical loading is essential for tendon development,…”
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    Journal Article
  10. 10

    Increased Ca2+ signaling through CaV 1.2 induces tendon hypertrophy with increased collagen fibrillogenesis and biomechanical properties by Li, Haiyin, Korcari, Antonion, Ciufo, David, Mendias, Christopher L, Rodeo, Scott A, Buckley, Mark R, Loiselle, Alayna E, Pitt, Geoffrey S, Cao, Chike

    Published in The FASEB journal (01-07-2023)
    “…Tendons are tension-bearing tissues transmitting force from muscle to bone for body movement. This mechanical loading is essential for tendon development,…”
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    Journal Article
  11. 11

    Identification of Periostin as a critical niche for myofibroblast dynamics and fibrosis during tendon healing by Ackerman, Jessica E., Muscat, Samantha N., Adjei-Sowah, Emmanuela, Korcari, Antonion, Nichols, Anne E.C., Buckley, Mark R., Loiselle, Alayna E.

    Published in Matrix biology (01-01-2024)
    “…•Periostin-lineage cells contribute to a transient but not persistent myofibroblast population.•Periostin serves as a supportive niche for myofibroblast…”
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    Journal Article
  12. 12

    Increased Ca 2+ signaling through Ca V 1.2 induces tendon hypertrophy with increased collagen fibrillogenesis and biomechanical properties by Li, Haiyin, Korcari, Antonion, Ciufo, David, Mendias, Christopher L, Rodeo, Scott A, Buckley, Mark R, Loiselle, Alayna E, Pitt, Geoffrey S, Cao, Chike

    Published in The FASEB journal (01-07-2023)
    “…Tendons are tension-bearing tissues transmitting force from muscle to bone for body movement. This mechanical loading is essential for tendon development,…”
    Get full text
    Journal Article
  13. 13

    Cue-Signal-Response Analysis in 3D Chondrocyte Scaffolds with Anabolic Stimuli by Neidlin, Michael, Korcari, Antonion, Macheras, Giorgos, Alexopoulos, Leonidas G.

    Published in Annals of biomedical engineering (01-02-2018)
    “…Articular cartilage is an avascular connective tissue responsible for bearing loads. Cell signaling plays a central role in cartilage homeostasis and tissue…”
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    Journal Article
  14. 14
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    Depletion of Scleraxis-lineage cells during tendon healing transiently impairs multi-scale restoration of tendon structure during early healing by Antonion Korcari, Samantha Muscat, Elizabeth McGinn, Mark R Buckley, Alayna E Loiselle

    Published in PloS one (01-01-2022)
    “…Tendons are composed of a heterogeneous cell environment, with Scleraxis-lineage (ScxLin) cells being the predominant population. Although ScxLin cells are…”
    Get full text
    Journal Article