Search Results - "Koral, K F"

MIRD Pamphlet No. 16: Techniques for Quantitative Radiopharmaceutical Biodistribution Data Acquisition and Analysis for Use in Human Radiation Dose Estimates by Siegel, Jeffry A, Thomas, Stephen R, Stubbs, James B, Stabin, Michael G, Hays, Marguerite T, Koral, Kenneth F, Robertson, James S, Howell, Roger W, Wessels, Barry W, Fisher, Darrell R, Weber, David A, Brill, A. Bertrand

“…This report describes recommended techniques for radiopharmaceutical biodistribution data acquisition and analysis in human subjects to estimate radiation…”
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Imaging, dosimetry, and radioimmunotherapy with iodine 131-labeled anti-CD37 antibody in B-cell lymphoma by Kaminski, M S, Fig, L M, Zasadny, K R, Koral, K F, DelRosario, R B, Francis, I R, Hanson, C A, Normolle, D P, Mudgett, E, Liu, C P

“…This study was undertaken to evaluate the tumor targeting, toxicity, and therapeutic potential of the anti-B-cell-reactive monoclonal antibody MB-1 (anti-CD37)…”
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Tumor-absorbed-dose estimates versus response in tositumomab therapy of previously untreated patients with follicular non-Hodgkin's lymphoma: preliminary report by Koral, K F, Dewaraja, Y, Clarke, L A, Li, J, Zasadny, K R, Rommelfanger, S G, Francis, I R, Kaminski, M S, Wahl, R L

“…I-131-radiolabeled tositumomab (Anti-B1 Antibody), in conjunction with unlabeled tositumomab, was employed in a phase II clinical trial for the therapy of 76…”
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Accurate dosimetry in I-131 radionuclide therapy using patient-specific, 3-dimensional methods for SPECT reconstruction and absorbed dose calculation by Dewaraja, Y K, Wilderman, S J, Ljungberg, Michael, Koral, K F, Zasadny, K, Kaminiski, M S

“…I-131 radionuclide therapy studies have not shown a strong relationship between tumor absorbed dose and response, possibly due to inaccuracies in activity…”
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SPECT Dual-Energy-Window Compton Correction: Scatter Multiplier Required for Quantification by Koral, Kenneth F, Swailem, Fayez M, Buchbinder, Steven, Clinthorne, Neal H, Rogers, W. Leslie, Tsui, Benjamin M.W

“…The dual-energy window Compton-scattering correction technique is defined here especially for accurate quantification of focal regions having higher than…”
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CT-SPECT Fusion Plus Conjugate Views for Determining Dosimetry in Iodine-131-Monoclonal Antibody Therapy of Lymphoma Patients by Koral, Kenneth F, Zasadny, Kenneth R, Kessler, Marc L, Luo, Jian-Qiao, Buchbinder, Steven F, Kaminski, Mark S, Francis, Isaac, Wahl, Richard L

“…A method for performing 131I quantitative SPECT imaging is described which uses the superimposition of markers placed on the skin to accomplish fusion of…”
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SPRINT II: a second generation single photon ring tomograph by Rogers, W.L., Clinthorne, N.H., Shao, L., Chiao, P., Ding, Y., Stamos, J.A., Koral, K.F.

“…SPRINT II is a stationary detector ring tomograph designed for brain imaging. Eleven two-dimensional sodium iodide camera modules that use maximum-likelihood…”
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Preliminary results from intensity‐based CT‐SPECT fusion in I‐131 anti‐B1 monoclonal‐antibody therapy of lymphoma by Koral, Kenneth F., Lin, Shuhong, Fessler, Jeffrey A., Kaminski, Mark S., Wahl, Richard L.

“…BACKGROUND In treatment of non‐Hodgkin's lymphoma patients with predose‐plus‐I‐131‐labeled anti‐B1 (anti‐CD20) monoclonal antibody, an intratherapy single…”
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SPECT Compton-Scattering Correction by Analysis of Energy Spectra by Koral, Kenneth F, Wang, Xiaoqin, Rogers, W. Leslie, Clinthorne, Neal H, Wang, Xiaohan

“…The hypothesis that energy spectra at individual spatial locations in single photon emission computed tomographic projection images can be analyzed to separate…”
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Monte Carlo evaluation of object shape effects in iodine-131 SPET tumor activity quantification by Dewaraja, Y K, Ljungberg, M, Koral, K F

“…In our clinical iodine-131 single-photon emission tomography (SPET) quantification for radioimmunotherapy, calibration and partial volume correction are based…”
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Correction for patient Compton scattering--current status by Koral, K F

“…Short communication…”
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Testing of local gamma-ray scatter fractions determined by spectral fitting by Koral, K F, Wang, X, Zasadny, K R, Clinthorne, N H, Rogers, W L, Floyd, Jr, C E, Jaszczak, R J

“…The spectral-fitting method of correction for gamma-ray Compton scattering within objects separates the unscattered and scattered components of locally…”
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Quantification of aspiration: methodological and clinical perspectives by Fig, L M, Koral, K F, Gross, M D, Shapiro, B

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Correlation of radiation absorbed doses to nodal metastases by Koral, K F, Adler, R S

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Field-Flood Requirements for Emission Computed Tomography with an Anger Camera by Rogers, W. L, Clinthorne, N. H, Harkness, B. A, Koral, K. F, Keyes, J. W., Jr

“…Emission computed tomography with a rotating camera places stringent requirements on camera uniformity and the stability of camera response. In terms of…”
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Fast Envelope Detection for Thinned Display of Finely Digitized Ultrasound Scans by Koral, K. F., Dupuy, M. E., Meyer, C. R.

“…In ultrasound tissue characterization, the backscattered RF signal is finely digitized. The signal envelope is displayed in a version thinned 1-8. Three…”
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Characterization of Scatter and Penetration Using Monte Carlo Simulation in 131I Imaging by Dewaraja, Yuni K, Ljungberg, Michael, Koral, Kenneth F

“…In 131I SPECT, image quality and quantification accuracy are degraded by object scatter as well as scatter and penetration in the collimator. The…”
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Quantitative autoradiographic evaluation of the influence of protein dose on monoclonal antibody distribution in human ovarian adenocarcinoma xenografts by YANG, F. E, BROWN, R. S, KORAL, K. F, CLAVO, A. C, JACKSON, G. A, WAHL, R. L

“…We studied the effect of monoclonal antibody protein dose on the uniformity of radioiodinated antibody distribution within tumor masses using quantitative…”
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Application of ART to time-coded emission tomography by Koral, K F, Rogers, W L

“…Devices for single-photon emission tomography currently take projections either in a plane over a full angular range (0--360 degrees) or in a volume with a…”
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Count-based monitoring of Anger-camera spectra--local energy shifts due to rotation by Swailem, F M, Koral, K F, Rogers, W L

“…This study reports on a spectral monitoring method in which (1) a small source fixed to the camera is used, (2) a narrow, offset window is set on the side of…”
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