Search Results - "Kopta, Laurice A."

Evidence for a primate origin of zoonotic Helicobacter suis colonizing domesticated pigs by Flahou, Bram, Rossi, Mirko, Bakker, Jaco, Langermans, Jan AM, Heuvelman, Edwin, Solnick, Jay V, Martin, Miriam E, O’Rourke, Jani, Ngoan, Le Duc, Hoa, Nguyen Xuan, Nakamura, Masahiko, Øverby, Anders, Matsui, Hidenori, Ota, Hiroyoshi, Matsumoto, Takehisa, Foss, Dennis L, Kopta, Laurice A, Omotosho, Oladipo, Franciosini, Maria Pia, Casagrande Proietti, Patrizia, Guo, Aizhen, Liu, Han, Borilova, Gabriela, Bracarense, Ana Paula, Lindén, Sara K, De Bruyckere, Sofie, Zhang, Guangzhi, De Witte, Chloë, Smet, Annemieke, Pasmans, Frank, Ducatelle, Richard, Corander, Jukka, Haesebrouck, Freddy

“…Helicobacter suis is the second most prevalent Helicobacter species in the stomach of humans suffering from gastric disease. This bacterium mainly inhabits the…”
Get full text

Inhibitors of HCV NS5B polymerase. Part 1: Evaluation of the southern region of (2Z)-2-(benzoylamino)-3-(5-phenyl-2-furyl)acrylic acid by Pfefferkorn, Jeffrey A., Greene, Meredith L., Nugent, Richard A., Gross, Rebecca J., Mitchell, Mark A., Finzel, Barry C., Harris, Melissa S., Wells, Peter A., Shelly, John A., Anstadt, Robert A., Kilkuskie, Robert E., Kopta, Laurice A., Schwende, Francis J.

“…[Display omitted] A novel series of nonnucleoside HCV NS5B polymerase inhibitors were prepared from (2Z)-2-(benzoylamino)-3-(5-phenyl-2-furyl)acrylic acid, a…”
Get full text

Inhibitors of HCV NS5B polymerase. Part 2: Evaluation of the northern region of (2 Z)-2-benzoylamino-3-(4-phenoxy-phenyl)-acrylic acid by Pfefferkorn, Jeffrey A., Nugent, Richard, Gross, Rebecca J., Greene, Meredith, Mitchell, Mark A., Reding, Matthew T., Funk, Lee A., Anderson, Rebecca, Wells, Peter A., Shelly, John A., Anstadt, Robert, Finzel, Barry C., Harris, Melissa S., Kilkuskie, Robert E., Kopta, Laurice A., Schwende, Francis J.

“…[Display omitted] A novel series of non-nucleoside HCV NS5B polymerase inhibitors was prepared from a (2 Z)-2-benzoylamino-3-(4-phenoxy-phenyl)-acrylic acid…”
Get full text

(−)-6-Chloro-2-[(1-furo[2,3-c]pyridin-5-ylethyl)thio]-4-pyrimidinamine, PNU-142721, a New Broad Spectrum HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitor by Wishka, Donn G, Graber, David R, Kopta, Laurice A, Olmsted, Robert A, Friis, Janice M, Hosley, John D, Adams, Wade J, Seest, Eric P, Castle, Thomas M, Dolak, Lester A, Keiser, Barbara J, Yagi, Yoshihiko, Jeganathan, Azhwarsamy, Schlachter, Stephen T, Murphy, Michael J, Cleek, Gary J, Nugent, Richard A, Poppe, Susan M, Swaney, Steven M, Han, Fusen, Watt, William, White, Wendy L, Poel, Toni-Jo, Thomas, Richard C, Voorman, Richard L, Stefanski, Kevin J, Stehle, Randall G, Tarpley, W. Gary, Morris, Joel

Get full text

Synthesis and Bioactivity of Novel Bis(heteroaryl)piperazine (BHAP) Reverse Transcriptase Inhibitors:  Structure−Activity Relationships and Increased Metabolic Stability of Novel Substituted Pyridine Analogs by Genin, Michael J., Poel, Toni J., Yagi, Yoshihiko, Biles, Carolyn, Althaus, Irene, Keiser, Barbara J., Kopta, Laurice A., Friis, Jan M., Reusser, Fritz, Adams, Wade J., Voorman, Richard L., Thomas, Richard C., Romero, Donna L.

“…The major route of metabolism of the bis(heteroaryl)piperazine (BHAP) class of reverse transcriptase inhibitors (RTIs), atevirdine and delavirdine, is via…”
Get full text

Synthesis and Structure−Activity Relationships of the (Alkylamino)piperidine-Containing BHAP Class of Non-Nucleoside Reverse Transcriptase Inhibitors:  Effect of 3-Alkylpyridine Ring Substitution by Genin, Michael J, Poel, Toni J, May, Paul D, Kopta, Laurice A, Yagi, Yoshihiko, Olmsted, Robert A, Friis, Janice M, Voorman, Richard L, Adams, Wade J, Thomas, Richard C, Romero, Donna L

“…Development of resistance to currently approved HIV therapies has continued to fuel research efforts to improve the metabolic stability and spectrum of…”
Get full text

A Drug Resistance Mutation in the Inhibitor Binding Pocket of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Impairs DNA Synthesis and RNA Degradation by Fan, Naisheng, Rank, Kenneth B, Slade, David E, Poppe, Susan M, Evans, David B, Kopta, Laurice A, Olmsted, Robert A, Thomas, Richard C, Tarpley, W. Gary, Sharma, Satish K

“…Selection of the IIIB strain of human immunodeficiency virus type (HIV-1) resistant to the (alkylamino)piperidine-bis(heteroaryl)piperazine (AAP-BHAP) U-104489…”
Get full text

Identification of Helicobacter suis in pig-producing regions of the United States by Foss, Dennis, Kopta, Laurice, Paquette, Jennifer, Bowersock, Terry, Choromanski, Leszek, Galvin, Jeffrey, Godbee, Traci, Laurinat, Robert, Sanchez, Margaret

“…Objectives: To develop a non-culture-based method to determine levels of Helicobacter suis infection in porcine stomachs and to test the method in a sample of…”
Get full text

Targeting Delavirdine/Atevirdine Resistant HIV-1:  Identification of (Alkylamino)piperidine-Containing Bis(heteroaryl)piperazines as Broad Spectrum HIV-1 Reverse Transcriptase Inhibitors by Romero, Donna L, Olmsted, Robert A, Poel, Toni Jo, Morge, Raymond A, Biles, Carolyn, Keiser, Barbara J, Kopta, Laurice A, Friis, Jan M, Hosley, John D, Stefanski, Kevin J, Wishka, Donn G, Evans, David B, Morris, Joel, Stehle, Randy G, Sharma, Satish K, Yagi, Yoshihiko, Voorman, Richard L, Adams, Wade J, Tarpley, W. Gary, Thomas, Richard C

“…A novel class of bis(heteroaryl)piperazine (BHAP) analogs which possesses the ability to inhibit NNRTI (non-nucleoside reverse transcriptase inhibitor)…”
Get full text

(Alkylamino) piperidine bis(heteroaryl)piperizine analogs are potent, broad-spectrum nonnucleoside reverse transcriptase inhibitors of drug-resistant isolates of human immunodeficiency virus type 1 (HIV-1) and select for drug-resistant variants of HIV-1IIIB with reduced replication phenotypes by Olmsted, R A, Slade, D E, Kopta, L A, Poppe, S M, Poel, T J, Newport, S W, Rank, K B, Biles, C, Morge, R A, Dueweke, T J, Yagi, Y, Romero, D L, Thomas, R C, Sharma, S K, Tarpley, W G

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Home cleaning-disinfection procedure for tracheal suction catheters by Shabino, C L, Erlandson, A L, Kopta, L A

“…The cost effectiveness of home care for pediatric tracheostomy patients has become a concern. One major cost component of this care is the tracheal suction…”
Get more information