Search Results - "Koppelman, G H"

Prediction of the severity of allergic reactions to foods by Pettersson, M. E., Koppelman, G. H., Flokstra‐de Blok, B. M. J., Kollen, B. J., Dubois, A. E. J.

“…Background There is currently considerable uncertainty regarding what the predictors of the severity of diagnostic or accidental food allergic reactions are,…”
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Colistin dry powder inhalation with the Twincer™: An effective and more patient friendly alternative to nebulization by Akkerman-Nijland, A. M, Grasmeijer, F, Kerstjens, H. A. M, Frijlink, H. W, van der Vaart, H, Vonk, J. M, Hagedoorn, P, Rottier, B. L, Koppelman, G. H, Akkerman, O. W

“…Background Nebulization of antimicrobial drugs such as tobramycin and colistin is a cornerstone in the treatment of patients with cystic fibrosis (CF) infected…”
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Toll-like receptor 2 and 4 genes influence susceptibility to adverse effects of traffic-related air pollution on childhood asthma by Kerkhof, M, Postma, D S, Brunekreef, B, Reijmerink, N E, Wijga, A H, de Jongste, J C, Gehring, U, Koppelman, G H

“…Epidemiological studies have reported adverse effects of ambient air pollution on the prevalence of asthma. Laboratory studies have suggested that innate…”
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Residential greenness is differentially associated with childhood allergic rhinitis and aeroallergen sensitization in seven birth cohorts by Fuertes, E., Markevych, I., Bowatte, G., Gruzieva, O., Gehring, U., Becker, A., Berdel, D., Berg, A., Bergström, A., Brauer, M., Brunekreef, B., Brüske, I., Carlsten, C., Chan‐Yeung, M., Dharmage, S. C., Hoffmann, B., Klümper, C., Koppelman, G. H., Kozyrskyj, A., Korek, M., Kull, I., Lodge, C., Lowe, A., MacIntyre, E., Pershagen, G., Standl, M., Sugiri, D., Wijga, A., Heinrich, J.

“…Background The prevalence of allergic rhinitis is high, but the role of environmental factors remains unclear. We examined cohort‐specific and combined…”
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Filaggrin mutations in the onset of eczema, sensitization, asthma, hay fever and the interaction with cat exposure by Schuttelaar, M. L. A., Kerkhof, M., Jonkman, M. F., Koppelman, G. H., Brunekreef, B., De Jongste, J. C., Wijga, A., McLean, W. H. I., Postma, D. S.

“…Background:  Filaggrin gene (FLG) mutations contribute to the development of eczema and asthma, but their contribution to sensitization and hay fever remains…”
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Retrospective observational cohort study regarding the effect of breastfeeding on challenge-proven food allergy by van Ginkel, C. D., van der Meulen, G. N., Bak, E., Flokstra-de Blok, B. M. J., Kollen, B. J., Koppelman, G. H., Dubois, A. E. J.

“…Background/objectives Human breast milk is generally regarded as the best nutrition for infants in their first months of life. Whether breastfeeding has a…”
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Lung function decline in asthma: association with inhaled corticosteroids, smoking and sex by Dijkstra, A, Vonk, J M, Jongepier, H, Koppelman, G H, Schouten, J P, ten Hacken, N H T, Timens, W, Postma, D S

“…Background: Inhaled corticosteroids (ICS) provide short term benefits in asthma but the long term effects are still unknown. Methods: 281 patients diagnosed…”
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Are allergic multimorbidities and IgE polysensitization associated with the persistence or re‐occurrence of foetal type 2 signalling? The MeDALL hypothesis by Bousquet, J., Anto, J. M., Wickman, M., Keil, T., Valenta, R., Haahtela, T., Lodrup Carlsen, K., Hage, M., Akdis, C., Bachert, C., Akdis, M., Auffray, C., Annesi‐Maesano, I., Bindslev‐Jensen, C., Cambon‐Thomsen, A., Carlsen, K. H., Chatzi, L., Forastiere, F., Garcia‐Aymerich, J., Gehrig, U., Guerra, S., Heinrich, J., Koppelman, G. H., Kowalski, M. L., Lambrecht, B., Lupinek, C., Maier, D., Melén, E., Momas, I., Palkonen, S., Pinart, M., Postma, D., Siroux, V., Smit, H. A., Sunyer, J., Wright, J., Zuberbier, T., Arshad, S. H., Nadif, R., Thijs, C., Andersson, N., Asarnoj, A., Ballardini, N., Ballereau, S., Bedbrook, A., Benet, M., Bergstrom, A., Brunekreef, B., Burte, E., Calderon, M., De Carlo, G., Demoly, P., Eller, E., Fantini, M. P., Hammad, H., Hohman, C., Just, J., Kerkhof, M., Kogevinas, M., Kull, I., Lau, S., Lemonnier, N., Mommers, M., Nawijn, M., Neubauer, A., Oddie, S., Pellet, J., Pin, I., Porta, D., Saes, Y., Skrindo, I., Tischer, C. G., Torrent, M., Hertzen, L.

“…Allergic diseases [asthma, rhinitis and atopic dermatitis (AD)] are complex. They are associated with allergen‐specific IgE and nonallergic mechanisms that may…”
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Perinatal risk factors for wheezing phenotypes in the first 8 years of life by Caudri, D., Savenije, O. E. M., Smit, H. A., Postma, D. S., Koppelman, G. H., Wijga, A. H., Kerkhof, M., Gehring, U., Hoekstra, M. O., Brunekreef, B., de Jongste, J. C.

“…Summary Background A novel data‐driven approach was used to identify wheezing phenotypes in pre‐schoolchildren aged 0–8 years, in the Prevention and Incidence…”
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TLR-related pathway analysis: novel gene-gene interactions in the development of asthma and atopy by Reijmerink, N.E, Bottema, R.W.B, Kerkhof, M, Gerritsen, J, Stelma, F.F, Thijs, C, van Schayck, C.P, Smit, H.A, Brunekreef, B, Koppelman, G.H, Postma, D.S

“…To cite this article: Reijmerink NE, Bottema RWB, Kerkhof M, Gerritsen J, Stelma FF, Thijs C, van Schayck CP, Smit HA, Brunekreef B, Koppelman GH, Postma DS…”
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Adult onset asthma and interaction between genes and active tobacco smoking: The GABRIEL consortium by Vonk, J M, Scholtens, S, Postma, D S, Moffatt, M F, Jarvis, D, Ramasamy, A, Wjst, M, Omenaas, E R, Bouzigon, E, Demenais, F, Nadif, R, Siroux, V, Polonikov, A V, Solodilova, M, Ivanov, V P, Curjuric, I, Imboden, M, Kumar, A, Probst-Hensch, N, Ogorodova, L M, Puzyrev, V P, Bragina, E Yu, Freidin, M B, Nolte, I M, Farrall, A M, Cookson, W O C M, Strachan, D P, Koppelman, G H, Boezen, H M

“…Genome-wide association studies have identified novel genetic associations for asthma, but without taking into account the role of active tobacco smoking. This…”
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Increased risk of asthma in overweight children born large for gestational age by Pinto, L. A., Guerra, S., Anto, J. M., Postma, D., Koppelman, G. H., Jongste, J. C., Gehring, U., Smit, H. A., Wijga, A. H.

“…Summary Background Being born large for gestational age (LGA) is a marker of increased growth velocity in fetal life and a risk factor for childhood…”
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Polymorphisms of the ADAM33 gene are associated with accelerated lung function decline in asthma by Jongepier, H., Boezen, H. M., Dijkstra, A., Howard, T. D., Vonk, J. M., Koppelman, G. H., Zheng, S. L., Meyers, D. A., Bleecker, E. R., Postma, D. S.

“…Summary Background Asthma is a genetically complex disease characterized by respiratory symptoms, intermittent airway obstruction and airway…”
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MeDALL (Mechanisms of the Development of ALLergy): an integrated approach from phenotypes to systems medicine by Bousquet, J., Anto, J., Auffray, C., Akdis, M., Cambon‐Thomsen, A., Keil, T., Haahtela, T., Lambrecht, B. N., Postma, D. S., Sunyer, J., Valenta, R., Akdis, C. A., Annesi‐Maesano, I., Arno, A., Bachert, C., Ballester, F., Basagana, X., Baumgartner, U., Bindslev‐Jensen, C., Brunekreef, B., Carlsen, K. H., Chatzi, L., Crameri, R., Eveno, E., Forastiere, F., Garcia‐Aymerich, J., Guerra, S., Hammad, H., Heinrich, J., Hirsch, D., Jacquemin, B., Kauffmann, F., Kerkhof, M., Kogevinas, M., Koppelman, G. H., Kowalski, M. L., Lau, S., Lodrup‐Carlsen, K. C., Lopez‐Botet, M., Lotvall, J., Lupinek, C., Maier, D., Makela, M. J., Martinez, F. D., Mestres, J., Momas, I., Nawijn, M. C., Neubauer, A., Oddie, S., Palkonen, S., Pin, I., Pison, C., Rancé, F., Reitamo, S., Rial‐Sebbag, E., Salapatas, M., Siroux, V., Smagghe, D., Torrent, M., Toskala, E., van Cauwenberge, P., van Oosterhout, A. J. M., Varraso, R., von Hertzen, L., Wickman, M., Wijmenga, C., Worm, M., Wright, J., Zuberbier, T.

“…To cite this article: Bousquet J, Anto J, Auffray C, Akdis M, Cambon‐Thomsen A, Keil T, Haahtela T, Lambrecht BN, Postma DS, Sunyer J, Valenta R, Akdis CA,…”
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E-cadherin gene polymorphisms in asthma patients using inhaled corticosteroids by LERODIAKONOU, D, POSTMA, D. S, KOPPELMAN, G. H, BOEZEN, H. M, GERRITSEN, J, TEN HACKEN, N, TIMENS, W, VONK, J. M

“…E-cadherins form intercellular junctions that maintain epithelial integrity. Epithelial integrity is impaired in asthma and can be restored by inhaled…”
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Serum micronutrient concentrations and childhood asthma: the PIAMA birth cohort study by van Oeffelen, A. A. M., Bekkers, M. B. M., Smit, H. A., Kerkhof, M., Koppelman, G. H., Haveman-Nies, A., van der A, D. L., Jansen, E. H. J. M., Wijga, A. H.

“…To cite this article: van Oeffelen AAM, Bekkers MBM, Smit HA, Kerkhof M, Koppelman GH, Haveman‐Nies A, van der A DL, Jansen EHJM, Wijga AH. Serum micronutrient…”
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Interleukin 13, CD14, pet and tobacco smoke influence atopy in three Dutch cohorts: the allergenic study by Bottema, R. W. B, Reijmerink, N. E, Kerkhof, M, Koppelman, G. H, Stelma, F. F, Gerritsen, J, Thijs, C, Brunekreef, B, van Schayck, C. P, Postma, D. S

“…Studying gene-environment interactions may elucidate the complex origins of atopic diseases but requires large study populations. Pooling data from several…”
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Developmental determinants in non-communicable chronic diseases and ageing by Bousquet, J, Anto, J M, Berkouk, K, Gergen, P, Antunes, J Pinto, Augé, P, Camuzat, T, Bringer, J, Mercier, J, Best, N, Bourret, R, Akdis, M, Arshad, S H, Bedbrook, A, Berr, C, Bush, A, Cavalli, G, Charles, M A, Clavel-Chapelon, F, Gillman, M, Gold, D R, Goldberg, M, Holloway, J W, Iozzo, P, Jacquemin, S, Jeandel, C, Kauffmann, F, Keil, T, Koppelman, G H, Krauss-Etschmann, S, Kuh, D, Lehmann, S, Carlsen, K C Lodrup, Maier, D, Méchali, M, Melén, E, Moatti, J P, Momas, I, Nérin, P, Postma, D S, Ritchie, K, Robine, J M, Samolinski, B, Siroux, V, Slagboom, P E, Smit, H A, Sunyer, J, Valenta, R, Van de Perre, P, Verdier, J M, Vrijheid, M, Wickman, M, Yiallouros, P, Zins, M

“…Prenatal and peri-natal events play a fundamental role in health, development of diseases and ageing (Developmental Origins of Health and Disease (DOHaD))…”
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Interaction of a 17q12 variant with both fetal and infant smoke exposure in the development of childhood asthma-like symptoms by van der Valk, R. J. P., Duijts, L., Kerkhof, M., Willemsen, S. P., Hofman, A., Moll, H. A., Smit, H. A., Brunekreef, B., Postma, D. S., Jaddoe, V. W. V., Koppelman, G. H., de Jongste, J. C.

“…Background Gene variants on chromosome 17q12‐21 are associated with an increased risk of childhood‐onset asthma, a risk known to be modified by environmental…”
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Eliciting dose is associated with tolerance development in peanut and cow's milk allergic children by Nitsche, C., Westerlaken‐van Ginkel, C. D., Kollen, B. J., Sprikkelman, A. B., Koppelman, G. H., Dubois, A. E. J.

“…Background Tolerance development rates differ between food allergies. Almost all previous studies have not used the gold standard method, the double‐blind,…”
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