Search Results - "Kopp, Sarah J."

Herpesvirus entry mediator is a serotype specific determinant of pathogenesis in ocular herpes by Karaba, Andrew H, Kopp, Sarah J, Longnecker, Richard

“…Infection with herpes simplex virus type 1 (HSV-1) and HSV-2 is initiated by viral glycoprotein D (gD) binding to a receptor on the host cell. Two receptors,…”
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Herpesvirus Entry Mediator and Nectin-1 Mediate Herpes Simplex Virus 1 Infection of the Murine Cornea by KARABA, Andrew H, KOPP, Sarah J, LONGNECKER, Richard

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Structure-Based Mutations in the Herpes Simplex Virus 1 Glycoprotein B Ectodomain Arm Impart a Slow-Entry Phenotype by Fan, Qing, Kopp, Sarah J, Connolly, Sarah A, Longnecker, Richard

“…Glycoprotein B (gB) is the conserved herpesvirus fusion protein, and it is required for the entry of herpesviruses. The structure of the postfusion…”
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Natural Selection of Glycoprotein B Mutations That Rescue the Small-Plaque Phenotype of a Fusion-Impaired Herpes Simplex Virus Mutant by Fan, Qing, Kopp, Sarah J, Byskosh, Nina C, Connolly, Sarah A, Longnecker, Richard

“…Glycoprotein B (gB) is a conserved viral fusion protein that is required for herpesvirus entry. To mediate fusion with the cellular membrane, gB refolds from a…”
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Herpesvirus Entry Mediator Binding Partners Mediate Immunopathogenesis of Ocular Herpes Simplex Virus 1 Infection by Park, Seo J, Riccio, Rachel E, Kopp, Sarah J, Ifergan, Igal, Miller, Stephen D, Longnecker, Richard

“…Ocular herpes simplex virus 1 (HSV-1) infection leads to an immunopathogenic disease called herpes stromal keratitis (HSK), in which CD4 T cell-driven…”
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Infection of neurons and encephalitis after intracranial inoculation of herpes simplex virus requires the entry receptor nectin-1 by Kopp, Sarah J, Banisadr, Ghazal, Glajch, Kelly, Maurer, Ulrike E, Grünewald, Kay, Miller, Richard J, Osten, Pavel, Spear, Patricia G

“…Multiple entry receptors can mediate infection of cells by herpes simplex virus (HSV), permitting alternative pathways for infection and disease. We…”
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Herpesvirus entry mediator on radiation-resistant cell lineages promotes ocular herpes simplex virus 1 pathogenesis in an entry-independent manner by Edwards, Rebecca G, Kopp, Sarah J, Karaba, Andrew H, Wilcox, Douglas R, Longnecker, Richard

“…Ocular herpes simplex virus 1 (HSV-1) infection leads to a potentially blinding immunoinflammatory syndrome, herpes stromal keratitis (HSK). Herpesvirus entry…”
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Pathogenesis of Neonatal Herpes Simplex 2 Disease in a Mouse Model Is Dependent on Entry Receptor Expression and Route of Inoculation by Kopp, Sarah J, Karaba, Andrew H, Cohen, Laura K, Banisadr, Ghazal, Miller, Richard J, Muller, William J

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Characterization of Sex Differences in Ocular Herpes Simplex Virus 1 Infection and Herpes Stromal Keratitis Pathogenesis of Wild-Type and Herpesvirus Entry Mediator Knockout Mice by Riccio, Rachel E, Park, Seo J, Longnecker, Richard, Kopp, Sarah J

“…Sex differences related to immune response and inflammation play a role in the susceptibility and pathogenesis of a variety of viral infections and disease (S…”
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Erratum for Riccio et al., "Characterization of Sex Differences in Ocular Herpes Simplex Virus 1 Infection and Herpes Stromal Keratitis Pathogenesis of Wild-Type and Herpesvirus Entry Mediator Knockout Mice" by Riccio, Rachel E, Park, Seo J, Longnecker, Richard, Kopp, Sarah J

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Functional interaction between herpes simplex virus type 2 gD and HVEM transiently dampens local chemokine production after murine mucosal infection by Yoon, Miri, Kopp, Sarah J, Taylor, Joann M, Storti, Christopher S, Spear, Patricia G, Muller, William J

“…Herpes virus entry mediator (HVEM) is one of two principal receptors mediating herpes simplex virus (HSV) entry into murine and human cells. It functions…”
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Influence of social determinants of health on breastfeeding intent in the United States by Kopp, Sarah J., Kelly, Elizabeth A., DeFranco, Emily A.

“…Background Breastfeeding rates in the United States are suboptimal despite public health recommendations that infants are fed breastmilk for their first year…”
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Herpes Simplex Virus-2 Glycoprotein Interaction with HVEM Influences Virus-Specific Recall Cellular Responses at the Mucosa by Kopp, Sarah J., Storti, Christopher S., Muller, William J.

“…Infection of susceptible cells by herpes simplex virus (HSV) requires the interaction of the HSV gD glycoprotein with one of two principal entry receptors,…”
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Age-Related Differences in Flashbulb Memories: A Meta-Analysis by Kopp, Sarah J., Sockol, Laura E., Multhaup, Kristi S.

“…Recent meta-analyses reveal age-related declines in short-term memory (STM), working memory, associative memory, prospective memory, face memory, recognition,…”
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Role of Nectin-1 and Herpesvirus Entry Mediator as Cellular Receptors for Herpes Simplex Virus 1 on Primary Murine Dermal Fibroblasts by Petermann, Philipp, Rahn, Elena, Thier, Katharina, Hsu, Mei-Ju, Rixon, Frazer J, Kopp, Sarah J, Knebel-Mörsdorf, Dagmar

“…The cellular proteins nectin-1 and herpesvirus entry mediator (HVEM) can both mediate the entry of herpes simplex virus 1 (HSV-1). We have recently shown how…”
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Murine Corneal Inflammation and Nerve Damage After Infection With HSV-1 Are Promoted by HVEM and Ameliorated by Immune-Modifying Nanoparticle Therapy by Edwards, Rebecca G, Kopp, Sarah J, Ifergan, Igal, Shui, Jr-Wen, Kronenberg, Mitchell, Miller, Stephen D, Longnecker, Richard

“…To determine cellular and temporal expression patterns of herpes virus entry mediator (HVEM, Tnfrsf14) in the murine cornea during the course of herpes simplex…”
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Perihematomal mitochondrial dysfunction after intracerebral hemorrhage by KIM-HAN, Jeong Sook, KOPP, Sarah J, DUGAN, Laura L, DIRINGER, Michael N

“…Recent measurements in intracerebral hemorrhage (ICH) patients suggest a primary reduction in brain metabolism is responsible for reduced cerebral blood flow…”
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Herpes simplex virus serotype and entry receptor availability alter CNS disease in a mouse model of neonatal HSV by Kopp, Sarah J., Ranaivo, Hantamalala R., Wilcox, Douglas R., Karaba, Andrew H., Wainwright, Mark S., Muller, William J.

“…Background: Outcomes of neonates with herpes simplex virus (HSV) encephalitis are worse after infection with HSV-2 when compared with HSV-1. The proteins…”
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Prolonged α-Tocopherol Deficiency Decreases Oxidative Stress and Unmasks α-Tocopherol-dependent Regulation of Mitochondrial Function in the Brain by Cuddihy, Sarah L., Ali, Sameh S., Musiek, Erik S., Lucero, Jacinta, Kopp, Sarah J., Morrow, Jason D., Dugan, Laura L.

“…Vitamin E is the major lipid-soluble chain-breaking antioxidant in mammals and plays an important role in normal development and physiology. Deficiency…”
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Longitudinal Characterization of Herpes Simplex Virus (HSV) Isolates Acquired From Different Sites in an Immune-Compromised Child: A New HSV Thymidine Kinase Mutation Associated With Resistance by Karaba, Andrew H., Cohen, Laura K., Glaubach, Taly, Kopp, Sarah J., Reichek, Jennifer L., Yoon, Hawke H., Zheng, Xiaotian T., Muller, William J.

“…Background. Herpes simplex virus resistance to acyclovir is well described in immune-compromised patients. Management of prolonged infection and recurrences in…”
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