Search Results - "Kopka, K"

F-18 labelled PSMA-1007: biodistribution, radiation dosimetry and histopathological validation of tumor lesions in prostate cancer patients by Giesel, Frederik L., Hadaschik, B., Cardinale, J., Radtke, J., Vinsensia, M., Lehnert, W., Kesch, C., Tolstov, Y., Singer, S., Grabe, N., Duensing, S., Schäfer, M., Neels, O. C., Mier, W., Haberkorn, U., Kopka, K., Kratochwil, C.

“…Purpose The prostate-specific membrane antigen (PSMA) targeted positron-emitting-tomography (PET) tracer 68 Ga-PSMA-11 shows great promise in the detection of…”
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Pharmacokinetic studies of [68 Ga]Ga-PSMA-11 in patients with biochemical recurrence of prostate cancer: detection, differences in temporal distribution and kinetic modelling by tissue type by Strauss, Dimitrios S., Sachpekidis, C., Kopka, K., Pan, L., Haberkorn, U., Dimitrakopoulou-Strauss, A.

“…Purpose [ 68  Ga]Ga-PSMA-11 is a promising radiopharmaceutical for detecting tumour lesions in prostate cancer, but knowledge of the pharmacokinetics is…”
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Novel Bispecific PSMA/GRPr Targeting Radioligands with Optimized Pharmacokinetics for Improved PET Imaging of Prostate Cancer by Liolios, C, Schäfer, M, Haberkorn, U, Eder, M, Kopka, K

“…A new series of bispecific radioligands (BRLs) targeting prostate-specific membrane antigen (PSMA) and gastrin releasing peptide receptor (GRPr), both…”
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Intra-individual comparison of (68)Ga-PSMA-11-PET/CT and multi-parametric MR for imaging of primary prostate cancer by Giesel, F L, Sterzing, F, Schlemmer, H P, Holland-Letz, T, Mier, W, Rius, M, Afshar-Oromieh, A, Kopka, K, Debus, J, Haberkorn, U, Kratochwil, C

“…Multi-parametric magnetic resonance imaging (MP-MRI) is currently the most comprehensive work up for non-invasive primary tumor staging of prostate cancer…”
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PSMA PET/CT with Glu-urea-Lys-(Ahx)-[68Ga(HBED-CC)] versus 3D CT volumetric lymph node assessment in recurrent prostate cancer by Giesel, Frederik L., Fiedler, H., Stefanova, M., Sterzing, F., Rius, M., Kopka, K., Moltz, J. H., Afshar-Oromieh, A., Choyke, P. L., Haberkorn, U., Kratochwil, C.

“…Purpose PET/CT with the PSMA ligand is a powerful new method for the early detection of nodal metastases in patients with biochemical relapse. The purpose of…”
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(68)Ga-PSMA-11 dynamic PET/CT imaging in biochemical relapse of prostate cancer by Sachpekidis, C, Eder, M, Kopka, K, Mier, W, Hadaschik, B A, Haberkorn, U, Dimitrakopoulou-Strauss, A

“…We aim to investigate the pharmacokinetics and distribution of the recently clinically introduced radioligand (68)Ga-PSMA-11 in men with recurrent prostate…”
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18F-PSMA-1007 multiparametric, dynamic PET/CT in biochemical relapse and progression of prostate cancer by Sachpekidis, Christos, Afshar-Oromieh, A., Kopka, K., Strauss, D. S., Pan, L., Haberkorn, U., Dimitrakopoulou-Strauss, A.

“…Objectives Aim of the present analysis is to investigate the biodistribution and pharmacokinetics of the recently clinically introduced radioligand 18…”
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68Ga-PSMA PET/CT in the evaluation of bone metastases in prostate cancer by Sachpekidis, Christos, Bäumer, P., Kopka, K., Hadaschik, B. A., Hohenfellner, M., Kopp-Schneider, A., Haberkorn, U., Dimitrakopoulou-Strauss, A.

“…Purpose The aims of this retrospective analysis were to compare 68 Ga-PSMA PET findings and low-dose CT findings (120 kV, 30 mA), and to obtain…”
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Treatment response evaluation with 18F-FDG PET/CT and 18F-NaF PET/CT in multiple myeloma patients undergoing high-dose chemotherapy and autologous stem cell transplantation by Sachpekidis, Christos, Hillengass, J., Goldschmidt, H., Wagner, B., Haberkorn, U., Kopka, K., Dimitrakopoulou-Strauss, A.

“…Aim The aim of this study was to assess the combined use of the radiotracers 18 F-FDG and 18 F-NaF in treatment response evaluation of a group of multiple…”
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SP-0602: PSMA ligands for diagnosis and therapy by Haberkorn, U, Babich, J.B, Kopka, K, Eder, M, Eisenhut, M

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Molecular imaging of matrix metalloproteinases in vivo using small molecule inhibitors for SPECT and PET by Wagner, S, Breyholz, H-J, Faust, A, Höltke, C, Levkau, B, Schober, O, Schäfers, M, Kopka, K

“…Matrix metalloproteinases (MMPs) are a family of zinc- and calcium-dependent secreted or membrane anchored endopeptidases. MMPs are involved in many…”
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Assessment of glucose metabolism and cellular proliferation in multiple myeloma: a first report on combined 18F-FDG and 18F-FLT PET/CT imaging by Sachpekidis, C., Goldschmidt, H., Kopka, K., Kopp-Schneider, A., Dimitrakopoulou-Strauss, A.

“…Background Despite the significant upgrading in recent years of the role of 18 F-FDG PET/CT in multiple myeloma (MM) diagnostics, there is a still unmet need…”
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Substituent Effect of Nitro Group on Aromaticity of Carbazole Rings by Radula-Janik, K., Kopka, K., Kupka, T., Ejsmont, K.

“…The molecular geometries of carbazole and its 17 nitro derivatives were optimized at the B3LYP/6-311++G(2d,2p) level of theory. The harmonic oscillator model…”
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The nonpeptidyl caspase binding radioligand (S)-1-(4-(2-[18F]Fluoroethoxy)-benzyl)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatin ([18F]CbR) as potential positron emission tomography-compatible apoptosis imaging agent by Faust, A, Wagner, S, Law, M P, Hermann, S, Schnöckel, U, Keul, P, Schober, O, Schäfers, M, Levkau, B, Kopka, K

“…Radiolabeled Annexin V-derivatives are well characterized phosphatidylserine-targeting biomarkers and considered as state-of-the-art tracers for non-invasive…”
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Specific biomarkers of receptors, pathways of inhibition and targeted therapies: pre-clinical developments by Waerzeggers, Y, Monfared, P, Viel, T, Faust, A, Kopka, K, Schäfers, M, Tavitian, B, Winkeler, A, Jacobs, A

“…A deeper understanding of the role of specific genes, proteins, pathways and networks in health and disease, coupled with the development of technologies to…”
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F18-PSMA-1007の集積分布は比放射能によりどう変化するか by 添田文彦, 渡部直史, 仲定宏, 劉雨薇, 堀次元気, Neels OC, Kopka K, 加藤弘樹, 巽光朗, 下瀬川恵久, Giesel FL, 畑澤順

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Non-invasive molecular imaging of beta-adrenoceptors in vivo: perspectives for PET-radioligands by Kopka, K, Law, M P, Breyholz, H-J, Faust, A, Höltke, C, Riemann, B, Schober, O, Schäfers, M, Wagner, S

“…Recently, the spectrum of molecular imaging devices such as positron emission tomography (PET) was further expanded by the now clinically available combined…”
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Non-invasive approaches to visualize the endothelin axis in vivo using state-of-the-art molecular imaging modalities by Höltke, C, Faust, A, Breyholz, H-J, Kopka, K, Schober, O, Riemann, B, Bremer, C, Schäfers, M, Wagner, S

“…The endothelin axis plays a major role in cardiovascular diseases and a number of human cancers. This review summarizes the work that has been published in the…”
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Reporter chemistry universalises radiochemistry by Kopka, K

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Synthesis of bifunctional HBED-based complexing ligands for use in theragnostic radiopharmaceuticals by Makarem, A., Litau, G., Kopka, K.

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