Search Results - "Kopinski, Piotr"

Mitochondrial DNA variation and cancer by Kopinski, Piotr K., Singh, Larry N., Zhang, Shiping, Lott, Marie T., Wallace, Douglas C.

“…Variation in the mitochondrial DNA (mtDNA) sequence is common in certain tumours. Two classes of cancer mtDNA variants can be identified: de novo mutations…”
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Aptamers in diagnostics and treatment of viral infections by Wandtke, Tomasz, Woźniak, Joanna, Kopiński, Piotr

“…Aptamers are in vitro selected DNA or RNA molecules that are capable of binding a wide range of nucleic and non-nucleic acid molecules with high affinity and…”
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Mitochondrial functions modulate neuroendocrine, metabolic, inflammatory, and transcriptional responses to acute psychological stress by Picard, Martin, McManus, Meagan J., Gray, Jason D., Nasca, Carla, Moffat, Cynthia, Kopinski, Piotr K., Seifert, Erin L., McEwen, Bruce S., Wallace, Douglas C.

“…The experience of psychological stress triggers neuroendocrine, inflammatory, metabolic, and transcriptional perturbations that ultimately predispose to…”
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Aptamers-Diagnostic and Therapeutic Solution in SARS-CoV-2 by Wandtke, Tomasz, Wędrowska, Ewelina, Szczur, Marcin, Przybylski, Grzegorz, Libura, Marek, Kopiński, Piotr

“…The SARS-CoV-2 virus is currently the most serious challenge to global public health. Its emergence has severely disrupted the functioning of health services…”
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Foxp3 Reprograms T Cell Metabolism to Function in Low-Glucose, High-Lactate Environments by Angelin, Alessia, Gil-de-Gómez, Luis, Dahiya, Satinder, Jiao, Jing, Guo, Lili, Levine, Matthew H., Wang, Zhonglin, Quinn, William J., Kopinski, Piotr K., Wang, Liqing, Akimova, Tatiana, Liu, Yujie, Bhatti, Tricia R., Han, Rongxiang, Laskin, Benjamin L., Baur, Joseph A., Blair, Ian A., Wallace, Douglas C., Hancock, Wayne W., Beier, Ulf H.

“…Immune cells function in diverse metabolic environments. Tissues with low glucose and high lactate concentrations, such as the intestinal tract or ischemic…”
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Lactate Limits T Cell Proliferation via the NAD(H) Redox State by Quinn, William J., Jiao, Jing, TeSlaa, Tara, Stadanlick, Jason, Wang, Zhonglin, Wang, Liqing, Akimova, Tatiana, Angelin, Alessia, Schäfer, Patrick M., Cully, Michelle D., Perry, Caroline, Kopinski, Piotr K., Guo, Lili, Blair, Ian A., Ghanem, Louis R., Leibowitz, Michael S., Hancock, Wayne W., Moon, Edmund K., Levine, Matthew H., Eruslanov, Evgeniy B., Wallace, Douglas C., Baur, Joseph A., Beier, Ulf H.

“…Immune cell function is influenced by metabolic conditions. Low-glucose, high-lactate environments, such as the placenta, gastrointestinal tract, and the tumor…”
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Regulation of nuclear epigenome by mitochondrial DNA heteroplasmy by Kopinski, Piotr K., Janssen, Kevin A., Schaefer, Patrick M., Trefely, Sophie, Perry, Caroline E., Potluri, Prasanth, Tintos-Hernandez, Jesus A., Singh, Larry N., Karch, Kelly R., Campbell, Sydney L., Doan, Mary T., Jiang, Helen, Nissim, Itzhak, Nakamaru-Ogiso, Eiko, Wellen, Kathryn E., Snyder, Nathaniel W., Garcia, Benjamin A., Wallace, Douglas C.

“…Diseases associated with mitochondrial DNA (mtDNA) mutations are highly variable in phenotype, in large part because of differences in the percentage of normal…”
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The Latest Achievements in the Construction of Influenza Virus Detection Aptasensors by Wędrowska, Ewelina, Wandtke, Tomasz, Piskorska, Elżbieta, Kopiński, Piotr

“…Aptamers are short fragments of nucleic acids, DNA or RNA that have the ability to bind selected proteins with high specificity and affinity. These properties…”
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Neutrophil extracellular traps (NETs) in aortic stenosis: Comparison of methods for assessment of NETs formation by Kopiński, Piotr, Kopytek, Magdalena, Ząbczyk, Michał, Undas, Anetta, Natorska, Joanna

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Rac2-MRC-cIII–generated ROS cause genomic instability in chronic myeloid leukemia stem cells and primitive progenitors by Nieborowska-Skorska, Margaret, Kopinski, Piotr K., Ray, Regina, Hoser, Grazyna, Ngaba, Danielle, Flis, Sylwia, Cramer, Kimberly, Reddy, Mamatha M., Koptyra, Mateusz, Penserga, Tyrone, Glodkowska-Mrowka, Eliza, Bolton, Elisabeth, Holyoake, Tessa L., Eaves, Connie J., Cerny-Reiterer, Sabine, Valent, Peter, Hochhaus, Andreas, Hughes, Timothy P., van der Kuip, Heiko, Sattler, Martin, Wiktor-Jedrzejczak, Wieslaw, Richardson, Christine, Dorrance, Adrienne, Stoklosa, Tomasz, Williams, David A., Skorski, Tomasz

“…Chronic myeloid leukemia in chronic phase (CML-CP) is induced by BCR-ABL1 oncogenic tyrosine kinase. Tyrosine kinase inhibitors eliminate the bulk of CML-CP…”
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Coronaviruses fusion with the membrane and entry to the host cell by Wędrowska, Ewelina, Wandtke, Tomasz, Senderek, Tomasz, Piskorska, Elżbieta, Kopiński, Piotr

“…Coronaviruses (CoVs) are positive-strand RNA viruses with the largest genome among all RNA viruses. They are able to infect many host, such as mammals or…”
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Challenges and Prospects for Alpha-1 Antitrypsin Deficiency Gene Therapy by Wozniak, Joanna, Wandtke, Tomasz, Kopinski, Piotr, Chorostowska-Wynimko, Joanna

“…Alpha-1 antitrypsin (AAT) is a protease inhibitor belonging to the serpin family. A number of identified mutations in the SERPINA1 gene encoding this protein…”
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The First Potentially Causal Genetic Variant Documented in a Polish Woman with Multiple Cavernous Malformations of the Brain by Szczygieł-Pilut, Elżbieta, Pilut, Daniel, Korostynski, Michal, Kopiński, Piotr, Potaczek, Daniel P, Wypasek, Ewa

“…Cerebral cavernous malformations (CCMs) are relatively common in the central nervous system. They occur in two forms, sporadic and familial (FCCMs). Three…”
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Targeting ACLY sensitizes castration-resistant prostate cancer cells to AR antagonism by impinging on an ACLY-AMPK-AR feedback mechanism by Shah, Supriya, Carriveau, Whitney J, Li, Jinyang, Campbell, Sydney L, Kopinski, Piotr K, Lim, Hee-Woong, Daurio, Natalie, Trefely, Sophie, Won, Kyoung-Jae, Wallace, Douglas C, Koumenis, Constantinos, Mancuso, Anthony, Wellen, Kathryn E

“…The androgen receptor (AR) plays a central role in prostate tumor growth. Inappropriate reactivation of the AR after androgen deprivation therapy promotes…”
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Different expression of immune checkpoint markers on bronchoalveolar lavage CD4+ cells: a comparison between hypersensitivity pneumonitis and sarcoidosis by Kopiński, Piotr, Wypasek, Ewa, Senderek, Tomasz, Wędrowska, Ewelina, Wandtke, Tomasz, Przybylski, Grzegorz

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Interleukin-27: Biological Properties and Clinical Application by Jankowski, Marek, Kopiński, Piotr, Goc, Anna

“…Interleukin (IL)-27 is a novel cytokine secreted by stimulated antigen-presenting cells. Initial studies on the biology of IL-27 provided evidence for its role…”
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Endobronchial ultrasound-guided needle aspiration in the non-small cell lung cancer staging by Szlubowski, Artur, Kużdżał, Jarosław, Kołodziej, Marcin, Soja, Jerzy, Pankowski, Juliusz, Obrochta, Anna, Kopiński, Piotr, Zieliński, Marcin

“…Objective: The aim of the study was to assess the diagnostic yield of the endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-NA) in the…”
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Thromboprophylaxis in hospitalized COVID-19 patients: the efficacy and safety of the approved hospital protocol by Kolanko, Emanuel, Senderek, Tomasz, Prokop-Staszecka, Anna, Kruk, Aleksandra, Broniatowska, Elżbieta, Konieczyńska, Małgorzata, Kopiński, Piotr, Pudło, Joanna, Undas, Anetta

“…INTRODUCTION Prothrombotic coagulopathy in COVID‑19 has led to a strong recommendation for thromboprophylaxis in all hospitalized patients, although there are…”
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Predicting Choroidal Nevus Transformation to Melanoma Using Machine Learning by Tailor, Prashant D., Kopinski, Piotr K., D’Souza, Haley S., Leske, David A., Olsen, Timothy W., Shields, Carol L., Shields, Jerry A., Dalvin, Lauren A.

“…To develop and validate machine learning (ML) models to predict choroidal nevus transformation to melanoma based on multimodal imaging at initial presentation…”
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Increased levels of interleukin 27 in patients with early clinical stages of non-small cell lung cancer by Kopiński, Piotr, Wandtke, Tomasz, Dyczek, Andrzej, Wędrowska, Ewelina, Roży, Adriana, Senderek, Tomasz, Przybylski, Grzegorz, Chorostowska-Wynimko, Joanna

“…INTRODUCTION    Interleukin 27 (IL‑27) is a cytokine secreted mostly by antigen‑presenting cells. It is important for the immune polarization of T helper‑1…”
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