Search Results - "Kopia, Gregory A."
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Twenty-eight-day efficacy and phamacokinetics of the sirolimus-eluting stent
Published in Coronary artery disease (01-05-2002)“…BACKGROUNDIn-stent restenosis is caused by neointimal hyperplasia. Sirolimus (rapamycin; Wyeth Research, Radnor, Pennsylvania, USA) inhibits vascular smooth…”
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Biocompatibility, bone healing, and safety evaluation in rabbits with an IlluminOss bone stabilization system
Published in Journal of orthopaedic research (01-10-2017)“…ABSTRACT Bone healing, biocompatibility, and safety employing the IlluminOss System (IS), comprised of an inflatable balloon filled with photopolymerizable…”
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Long-term effects of polymer-based, slow-release, sirolimus-eluting stents in a porcine coronary model
Published in Cardiovascular research (01-09-2004)“…Stent-based delivery of sirolimus (SRL) has shown reduction in neointimal hyperplasia and restenosis. The purpose of this study was to evaluate the chronic…”
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TCT-552 Particulates from Hydrophilic Coated Guiding Sheaths Embolize to the Brain
Published in Journal of the American College of Cardiology (16-09-2014)“…Results The Cook guiding sheath was associated with intravascular accumulation of an amorphous, non-refractile, non-crystalline, and non-birefringent embolic…”
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Evaluation of an intramedullary bone stabilization system using a light-curable monomer in sheep
Published in Journal of biomedical materials research. Part B, Applied biomaterials (01-02-2016)“…Percutaneous intramedullary fixation may provide an ideal method for stabilization of bone fractures, while avoiding the need for large tissue dissections…”
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Particulates from hydrophilic-coated guiding sheaths embolise to the brain
Published in EuroIntervention (01-03-2016)“…We sought to evaluate the incidence of embolic material in porcine brains following vascular interventions using hydrophilic-coated sheaths. A new…”
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CRT-306 Particulates from Hydrophilic Coated Guiding Sheaths Embolize to the Brain
Published in JACC. Cardiovascular interventions (01-02-2015)Get full text
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Safety and pharmacokinetics of sirolimus-eluting stents in the canine cerebral vasculature: 180 day assessment
Published in Neurosurgery (01-10-2006)“…We evaluated local and systemic pharmacokinetics and pharmacodynamics of sirolimus-eluting stents (SES) in canine cerebral vessels. SES (1.5 x 8 mm, 79…”
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Update on sirolimus drug-eluting stents
Published in Current pharmaceutical design (01-01-2004)“…Percutaneous transluminal coronary angioplasty (PTCA) has become the main method of coronary revascularization. However, despite technical advancement,…”
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Segmental vessel wall shear stress and neointimal formation after sirolimus-eluting stent implantation: physiological insights in a porcine coronary model
Published in Cardiovascular revascularization medicine (01-04-2005)“…Low vessel-wall shear stress promotes atherosclerosis and restenosis. We conducted serial analysis of vessel-wall shear stress following placement of metal and…”
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Particulates from Hydrophilic-Coated Guiding Sheaths Embolize to the Brain
Published in EuroIntervention (20-03-2016)Get full text
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Importance of receptor regulation in the pathophysiology and therapy of congestive heart failure
Published in The American journal of medicine (28-02-1986)“…The available data indicate that the beta-adrenergic receptors that mediate positive inotropic responses undergo "down-regulation," a cellularly mediated…”
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Antagonism of vasopressin-induced coronary artery constriction by the vasopressin antagonist d(CH2)5Tyr(Me)-AVP
Published in Journal of cardiovascular pharmacology (01-09-1985)“…d(CH2)5Tyr(Me)-AVP is a potent inhibitor of the systemic vasoconstrictor action of vasopressin (AVP). In order to examine the effectiveness of this agent in…”
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Evaluation of the acute hemodynamic effects and pharmacokinetics of coronary thrombolysis produced by intravenous tissue-type plasminogen activator in the anesthetized dog
Published in Journal of cardiovascular pharmacology (01-09-1988)“…The thrombolytic dose-response effectiveness and pharmacokinetics of tissue-type plasminogen activator (rt-PA) was evaluated in anesthetized, open-chest dogs…”
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1139-49 Sirolimus-eluting stents: Pharmacokinetics in blood, vessel, and myocardium in a porcine coronary model
Published in Journal of the American College of Cardiology (03-03-2004)Get full text
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Safety and pharmacokinetics of sirolimus-eluting stents in the canine cerebral vasculature : 180 day assessment. Commentary
Published in Neurosurgery (2006)Get full text
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Antiarrhythmic and electrophysiologic actions of clofilium in experimental canine models
Published in European journal of pharmacology (08-10-1985)“…Clofilium was studied in three experimental models. In non-ischemic and chronically infarcted canine hearts, clofilium (0.5-2 mg/kg) produced a dose-dependent…”
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Antifibrillatory action of bretylium: role of the sympathetic nervous system
Published in Pharmacology (1987)“…This study was performed to assess the role of cardiac sympathetic nerves in the in vivo antifibrillatory action of bretylium using the technique of…”
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Cardiac arrhythmias induced by guanethidine in cats anesthetized with halothane
Published in European journal of pharmacology (05-12-1980)“…Rapid i.v. administration of guanethidine provokes severe and sustained ventricular arrhythmias in cats anesthetized with halothane. The arrhythmias include…”
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