Search Results - "Kopell, Nancy J"

Beyond the Connectome: The Dynome by Kopell, Nancy J., Gritton, Howard J., Whittington, Miles A., Kramer, Mark A.

“…The human connectome will provide a detailed mapping of the brain’s connectivity, with fundamental insights for health and disease. However, further…”
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Thalamic model of awake alpha oscillations and implications for stimulus processing by Vijayan, Sujith, Kopell, Nancy J

“…We describe a unique conductance-based model of awake thalamic alpha and some of its implications for function. The full model includes a model for a…”
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Thalamocortical model for a propofol-induced α-rhythm associated with loss of consciousness by Ching, ShiNung, Cimenser, Aylin, Purdon, Patrick L, Brown, Emery N, Kopell, Nancy J

“…Recent data reveal that the general anesthetic propofol gives rise to a frontal α-rhythm at dose levels sufficient to induce loss of consciousness. In this…”
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Parietal low beta rhythm provides a dynamical substrate for a working memory buffer by Gelastopoulos, Alexandros, Whittington, Miles A., Kopell, Nancy J.

“…Working memory (WM) is a component of the brain’s memory systems vital for interpretation of sequential sensory inputs and consequent decision making…”
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neurophysiological–metabolic model for burst suppression by Ching, ShiNung, Purdon, Patrick L, Vijayan, Sujith, Kopell, Nancy J, Brown, Emery N

“…Burst suppression is an electroencepholagram (EEG) pattern in which high-voltage activity alternates with isoelectric quiescence. It is characteristic of an…”
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Theta-gamma coupling increases during the learning of item-context associations by Tort, Adriano B.L, Komorowski, Robert W, Manns, Joseph R, Kopell, Nancy J, Eichenbaum, Howard

“…Phase-amplitude cross-frequency coupling (CFC) between theta (4-12 Hz) and gamma (30-100 Hz) oscillations occurs frequently in the hippocampus. However, it…”
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Top-down beta rhythms support selective attention via interlaminar interaction: a model by Lee, Jung H, Whittington, Miles A, Kopell, Nancy J

“…Cortical rhythms have been thought to play crucial roles in our cognitive abilities. Rhythmic activity in the beta frequency band, around 20 Hz, has been…”
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Electroencephalogram signatures of loss and recovery of consciousness from propofol by Purdon, Patrick L, Pierce, Eric T, Mukamel, Eran A, Prerau, Michael J, Walsh, John L, Wong, Kin Foon K, Salazar-Gomez, Andres F, Harrell, Priscilla G, Sampson, Aaron L, Cimenser, Aylin, Ching, ShiNung, Kopell, Nancy J, Tavares-Stoeckel, Casie, Habeeb, Kathleen, Merhar, Rebecca, Brown, Emery N

“…Unconsciousness is a fundamental component of general anesthesia (GA), but anesthesiologists have no reliable ways to be certain that a patient is unconscious…”
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Dynamic cross-frequency couplings of local field potential oscillations in rat striatum and hippocampus during performance of a T-maze task by Tort, Adriano B.L, Kramer, Mark A, Thorn, Catherine, Gibson, Daniel J, Kubota, Yasuo, Graybiel, Ann M, Kopell, Nancy J

“…Oscillatory rhythms in different frequency ranges mark different behavioral states and are thought to provide distinct temporal windows that coherently bind…”
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Brain Rhythms Connect Impaired Inhibition to Altered Cognition in Schizophrenia by Pittman-Polletta, Benjamin R, Kocsis, Bernat, Vijayan, Sujith, Whittington, Miles A, Kopell, Nancy J

“…Abstract In recent years, schizophrenia research has focused on inhibitory interneuron dysfunction at the level of neurobiology and on cognitive impairments at…”
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Rates and Rhythms: A Synergistic View of Frequency and Temporal Coding in Neuronal Networks by Ainsworth, Matt, Lee, Shane, Cunningham, Mark O., Traub, Roger D., Kopell, Nancy J., Whittington, Miles A.

“…In the CNS, activity of individual neurons has a small but quantifiable relationship to sensory representations and motor outputs. Coactivation of a few 10s to…”
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Gamma oscillations mediate stimulus competition and attentional selection in a cortical network model by Börgers, Christoph, Epstein, Steven, Kopell, Nancy J

“…Simultaneous presentation of multiple stimuli can reduce the firing rates of neurons in extrastriate visual cortex below the rate elicited by a single…”
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Flexible resonance in prefrontal networks with strong feedback inhibition by Sherfey, Jason S, Ardid, Salva, Hass, Joachim, Hasselmo, Michael E, Kopell, Nancy J

“…Oscillations are ubiquitous features of brain dynamics that undergo task-related changes in synchrony, power, and frequency. The impact of those changes on…”
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Interacting rhythms enhance sensitivity of target detection in a fronto-parietal computational model of visual attention by Aussel, Amélie, Fiebelkorn, Ian C, Kastner, Sabine, Kopell, Nancy J, Pittman-Polletta, Benjamin Rafael

“…Even during sustained attention, enhanced processing of attended stimuli waxes and wanes rhythmically, with periods of enhanced and relatively diminished…”
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Hippocampal theta rhythm and its coupling with gamma oscillations require fast inhibition onto parvalbumin-positive interneurons by Wulff, Peer, Ponomarenko, Alexey A, Bartos, Marlene, Korotkova, Tatiana M, Fuchs, Elke C, Bähner, Florian, Both, Martin, Tort, Adriano B.L, Kopell, Nancy J, Wisden, William, Monyer, Hannah

“…Hippocampal theta (5-10 Hz) and gamma (35-85 Hz) oscillations depend on an inhibitory network of GABAergic interneurons. However, the lack of methods for…”
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Differential contributions of synaptic and intrinsic inhibitory currents to speech segmentation via flexible phase-locking in neural oscillators by Pittman-Polletta, Benjamin R, Wang, Yangyang, Stanley, David A, Schroeder, Charles E, Whittington, Miles A, Kopell, Nancy J

“…Current hypotheses suggest that speech segmentation-the initial division and grouping of the speech stream into candidate phrases, syllables, and phonemes for…”
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Frontal beta-theta network during REM sleep by Vijayan, Sujith, Lepage, Kyle Q, Kopell, Nancy J, Cash, Sydney S

“…We lack detailed knowledge about the spatio-temporal physiological signatures of REM sleep, especially in humans. By analyzing intracranial electrode data from…”
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Sharp edge artifacts and spurious coupling in EEG frequency comodulation measures by Kramer, Mark A., Tort, Adriano B.L., Kopell, Nancy J.

“…Recent electroencephalogram (EEG), electrocorticogram (ECoG), and local field potential (LFP) observations suggest that distinct frequency bands interact…”
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Background Gamma Rhythmicity and Attention in Cortical Local Circuits: A Computational Study by Börgers, Christoph, Epstein, Steven, Kopell, Nancy J.

“…We describe a simple computational model, based on generic features of cortical local circuits, that links cholinergic neuromodulation, gamma rhythmicity, and…”
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Gamma oscillations and stimulus selection by Börgers, Christoph, Kopell, Nancy J

“…More coherent excitatory stimuli are known to have a competitive advantage over less coherent ones. We show here that this advantage is amplified greatly when…”
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