Search Results - "Kopecki, Zlatko"

Comparing Redox and Intracellular Signalling Responses to Cold Plasma in Wound Healing and Cancer by Abdo, Adrian I, Kopecki, Zlatko

“…Cold plasma (CP) is an ionised gas containing excited molecules and ions, radicals, and free electrons, and which emits electric fields and UV radiation. CP is…”
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pH-Responsive "Smart" Hydrogel for Controlled Delivery of Silver Nanoparticles to Infected Wounds by Haidari, Hanif, Kopecki, Zlatko, Sutton, Adam T, Garg, Sanjay, Cowin, Allison J, Vasilev, Krasimir

“…Persistent wound infections have been a therapeutic challenge for a long time. Current treatment approaches are mostly based on the delivery of antibiotics,…”
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Antibacterial hydrogel therapy for eradication of wound associated polymicrobial biofilms by Haidari, Hanif, Kopecki, Zlatko

“…The recalcitrance of bacterial biofilms to current antimicrobials has presented a major cause of clinical recurrence of wound infections. These…”
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Immunological Memory in Imiquimod-Induced Murine Model of Psoriasiform Dermatitis by Fenix, Kevin, Wijesundara, Danushka K, Cowin, Allison J, Grubor-Bauk, Branka, Kopecki, Zlatko

“…Psoriasis is a common chronic inflammatory skin condition manifested by T cell responses and characterized by preferential recurrence at previously inflamed…”
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Editorial: Inflammation in Healing and Regeneration of Cutaneous Wounds by Cowin, Allison J, Bayat, Ardeshir, Murray, Rachael Z, Kopecki, Zlatko

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Eradication of Mature Bacterial Biofilms with Concurrent Improvement in Chronic Wound Healing Using Silver Nanoparticle Hydrogel Treatment by Haidari, Hanif, Bright, Richard, Garg, Sanjay, Vasilev, Krasimir, Cowin, Allison J, Kopecki, Zlatko

“…Biofilm-associated infections are a major cause of impaired wound healing. Despite the broad spectrum of anti-bacterial benefits provided by silver…”
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Development of Microneedles for Antimicrobial Drug Delivery: A Comprehensive Review on Applications in Wound Infection Management by Haidari, Hanif, Bright, Richard, Yu, Yunlong, Vasilev, Krasimir, Kopecki, Zlatko

“…Microneedles (MNs) have emerged as a promising transdermal antimicrobial delivery system, providing precise and localized drug delivery while complemented with…”
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Skin Barrier and Autoimmunity-Mechanisms and Novel Therapeutic Approaches for Autoimmune Blistering Diseases of the Skin by Stevens, Natalie E, Cowin, Allison J, Kopecki, Zlatko

“…One of the most important functions of the skin besides regulating internal body temperature includes formation of the barrier between the organism and the…”
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Overexpression of Flii during Murine Embryonic Development Increases Symmetrical Division of Epidermal Progenitor Cells by Yang, Gink N., Ahangar, Parinaz, Strudwick, Xanthe L., Kopecki, Zlatko, Cowin, Allison J.

“…Epidermal progenitor cells divide symmetrically and asymmetrically to form stratified epidermis and hair follicles during late embryonic development…”
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Increased Expression of Flightless I in Cutaneous Squamous Cell Carcinoma Affects Wnt/β-Catenin Signaling Pathway by Yang, Gink N, Strudwick, Xanthe L, Bonder, Claudine S, Kopecki, Zlatko, Cowin, Allison J

“…Cutaneous squamous cell carcinoma (cSCC) accounts for 25% of cutaneous malignancies diagnosed in Caucasian populations. Surgical removal in combination with…”
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Deferiprone-Gallium-Protoporphyrin Chitogel Decreases Pseudomonas aeruginosa Biofilm Infection without Impairing Wound Healing by Kennewell, Tahlia L, Haidari, Hanif, Mashtoub, Suzanne, Howarth, Gordon S, Bennett, Catherine, Cooksley, Clare M, Wormald, Peter John, Cowin, Allison J, Vreugde, Sarah, Kopecki, Zlatko

“…is one of the most common pathogens encountered in clinical wound infections. Clinical studies have shown that infection results in a larger wound area,…”
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Bioluminescent murine models of bacterial sepsis and scald wound infections for antimicrobial efficacy testing by Ogunniyi, Abiodun D, Kopecki, Zlatko, Hickey, Elizabeth E, Khazandi, Manouchehr, Peel, Emma, Belov, Katherine, Boileau, Alexandra, Garg, Sanjay, Venter, Henrietta, Chan, Wei Yee, Hill, Peter B, Page, Stephen W, Cowin, Allison J, Trott, Darren J

“…There are very few articles in the literature describing continuous models of bacterial infections that mimic disease pathogenesis in humans and animals…”
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Recombinant Leucine-Rich Repeat Flightless-Interacting Protein-1 Improves Healing of Acute Wounds through Its Effects on Proliferation Inflammation and Collagen Deposition by Kopecki, Zlatko, Stevens, Natalie E, Yang, Gink N, Melville, Elizabeth, Cowin, Allison J

“…Wound healing is an increasing clinical problem involving substantial morbidity, mortality, and rising health care costs. Leucine-rich repeat…”
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Cytoskeletal Regulation of Inflammation and Its Impact on Skin Blistering Disease Epidermolysis Bullosa Acquisita by Kopecki, Zlatko, Ludwig, Ralf J, Cowin, Allison J

“…Actin remodelling proteins regulate cytoskeletal cell responses and are important in both innate and adaptive immunity. These responses play a major role in…”
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Flightless I Alters the Inflammatory Response and Autoantibody Profile in an OVA-Induced Atopic Dermatitis Skin-Like Disease by Kopecki, Zlatko, Stevens, Natalie E, Chong, Heng T, Yang, Gink N, Cowin, Allison J

“…Atopic dermatitis (AD) is a chronic pruritic inflammatory skin disease characterized by excessive inflammation and disrupted skin barrier function. Although…”
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A Multifunctional Wearable Device with a Graphene/Silver Nanowire Nanocomposite for Highly Sensitive Strain Sensing and Drug Delivery by Shi, Ge, Liu, Tianqing, Kopecki, Zlatko, Cowin, Allison, Lee, Ivan, Pai, Jing-Hong, Lowe, Sean E., Zhong, Yu Lin

“…Advances in wearable, highly sensitive and multifunctional strain sensors open up new opportunities for the development of wearable human interface devices for…”
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Lipid Liquid Crystal Nanoparticles: Promising Photosensitizer Carriers for the Treatment of Infected Cutaneous Wounds by Awad, Muhammed, Kopecki, Zlatko, Barnes, Timothy J, Wignall, Anthony, Joyce, Paul, Thomas, Nicky, Prestidge, Clive A

“…Cutaneous chronic wounds impose a silent pandemic that affects the lives of millions worldwide. The delayed healing process is usually complicated by…”
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In vitro analysis of the effect of Flightless I on murine tenocyte cellular functions by Jackson, Jessica E, Kopecki, Zlatko, Anderson, Peter J, Cowin, Allison J

“…Healing of tendons after injury involves the proliferation of tenocytes and the production of extracellular matrix; however, their capacity to heal is limited…”
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Increasing the level of cytoskeletal protein Flightless I reduces adhesion formation in a murine digital flexor tendon model by Jackson, Jessica E, Kopecki, Zlatko, Anderson, Peter J, Cowin, Allison J

“…Surgical repair of tendons is common, but function is often limited due to the formation of flexor tendon adhesions which reduce the mobility and use of the…”
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Regulation of Focal Adhesions by Flightless I Involves Inhibition of Paxillin Phosphorylation via a Rac1-Dependent Pathway by Kopecki, Zlatko, O'Neill, Geraldine M., Arkell, Ruth M., Cowin, Allison J.

“…Flightless I (Flii) is an actin-remodeling protein that influences diverse processes including cell migration and gene transcription and links signal…”
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