Search Results - "Kopantsev, E P"
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Evaluation of the toxic effects evoked by the transient expression of protease genes from human pathogens in HEK293 cells
Published in Applied biochemistry and microbiology (01-12-2013)“…A method for the in vitro evaluation of the toxic effects occurring in human cell lines upon the expression of genes from a range of pathogens is proposed. The…”
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Downregulation of RBSP3/CTDSPL, NPRL2/G21, RASSF1A, ITGA9, HYAL1, and HYAL2 in non-small cell lung cancer
Published in Molecular biology (New York) (01-12-2008)“…Chromosomal and genome abnormalities of 3p are frequent in many epithelial tumors, including lung cancer. Several critical regions with a high frequency of…”
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Expression of FTL and FTH genes encoding ferritin subunits in lung and renal carcinomas
Published in Molecular biology (New York) (01-12-2009)“…Numerous human cancers are accompanied with the increase of ferritin content in blood serum. Ferritin is composed of light and heavy chains, encoded by FTL and…”
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Fibroblast growth factors and pancreas organogenesis
Published in Biochemistry (Moscow). Supplement. Series B, Biomedical chemistry (01-10-2017)“…Fibroblast growth factors (FGFs) are growth factors that regulate many important biological processes, including proliferation and differentiation of embryonic…”
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The role of the signaling pathway FGF/FGFR in pancreatic cancer
Published in Biochemistry (Moscow). Supplement. Series B, Biomedical chemistry (01-04-2017)“…Fibroblast growth factors (FGFs) are signaling molecules with a wide range of actions that are involved in various processes in the body. Specifically for…”
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Expression of Therapeutic Gene FCU1 Sensitizes Pancreatic Cancer Cells to 5-Fluorocytosine and Enhances the Cytotoxic Effect of 5-Fluorouracil
Published in Bulletin of experimental biology and medicine (01-10-2016)“…Hybrid therapeutic gene FCU1 gene was cloned into a lentiviral expression vector and the therapeutic effect of its expression was studied in three pancreatic…”
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Comparative activity of several promoters in driving NIS expression in melanoma cells
Published in Molecular biology (New York) (2014)“…Targeted drug delivery systems are special importance for developing gene therapeutic drugs that recognize and eliminate tumor cells. It is desirable that…”
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Adult stem cells and other cancer residents. Part II
Published in Molecular genetics, microbiology and virology (01-10-2015)“…In this review, we have attempted to generalize recent data on adult stem cells as the most likely cells, according to the current dominant paradigm, in which…”
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Genes potentially associated with Cisplatin resistance of lung cancer cells
Published in Doklady. Biochemistry and biophysics (01-06-2011)“…A study investigated genes potentially associated with Cisplatin resistance of lung cancer cells. The greatest differences were found for 17 genes, and data…”
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Study of transactivation effect on transcription by Tat-TAR-system of human immunodeficiency virus type 1 (HIV-1) in non-lymphoid cells HEK293 and Calu-1
Published in Molekulârnaâ genetika, mikrobiologiâ i virusologiâ (2009)“…An important problem in the development of gene therapy approaches in oncology is the necessity of using promoters providing specific and high level of gene…”
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Study of transactivation effect on transcription by Tat-TAR system of human immunodeficiency virus type I (HIV-I) in nonlymphoid cells HEK293 and Calu-1
Published in Molecular genetics, microbiology and virology (01-06-2009)“…An important problem in the development of gene therapy approaches in oncology is the necessity of using promoters that provide specific and high levels of…”
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Transcription of TIMP3, DAPK1, and AKR1B10 in squamous-cell lung cancer
Published in Molecular biology (New York) (01-11-2006)“…Lung cancer is among the most common neoplasms in Russia, the United States, and in Western Europe and is accompanied by changes in the functional activity of…”
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Role of fibroblast growth factors in pancreatic cancer
Published in Biomeditsinskaia khimiia (01-11-2016)“…Fibroblast growth factors belong to a family of growth factors that are involved in various processes in organism and have a wide range of biological…”
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Adult stem cells and other cancer residents. Part I
Published in Molecular genetics, microbiology and virology (01-07-2015)“…The present review is an attempt to summarize the recent data on adult stem cells which, according to the present dominant paradigm, most probably can be…”
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Comparative analysis of activity of different promoters for NIS gene expression in melanoma cells
Published in Molekuliarnaia biologiia (01-01-2014)“…Development of targeted drug delivery system is key problem of cancer gene therapy. To ensure specific delivery of these therapeutic compounds to the tumor it…”
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Quantitative comparison of expression for genes linked in bicistronic vectors via ires or 2A-peptide of porcine teschovirus-1 sequence
Published in Bioorganicheskaia khimiia (01-07-2013)“…Simultaneous expression of multiple target genes is often required in biotechnology. Multicistronic vectors coding for several proteins are being actively…”
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Comparative analysis of herpes simplex virus thymidine kinase gene expression potentiation via HIV-1 Tat-TAR-system and cancer-specific promoters in p53(+) and p53(-) cells
Published in Molekuliarnaia biologiia (01-05-2010)“…Tumor-specific promoters are predominantly active and ensure expression of the gene under control exclusively in cancer cells. However, a low activity of the…”
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Structure and functions of isoforms of polyfunctional tumoral suppressor PML
Published in Molekulârnaâ genetika, mikrobiologiâ i virusologiâ (2009)“…Polyfunctional protein PML contributes significantly in vital activity of cell. 11 isoforms of PML differ from one another by C-terminal domain. In spite of…”
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Structure and functions of isoforms of polyfunctional tumoral suppressor PML
Published in Molecular genetics, microbiology and virology (01-06-2009)“…Polyfunctional protein PML contributes significantly to the vital activity of the cell. Eleven isoforms of PML differ from one another in their C-terminal…”
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