Search Results - "Kooyman, D. L."

In Vivo Transfer of GPI-Linked Complement Restriction Factors from Erythrocytes to the Endothelium by Kooyman, D. L., Byrne, G. W., McClellan, S., Nielsen, D., Tone, M., Waldmann, H., Coffman, T. M., McCurry, K. R., Platt, J. L., Logan, J. S.

“…Many proteins are associated with the outer layer of the cell membrane through a posttranslationally added glycosyl phosphatidylinositol (GPI) anchor. The…”
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Construction of a quinoa (Chenopodium quinoa Willd.) BAC library and its use in identifying genes encoding seed storage proteins by Stevens, M.R, Coleman, C.E, Parkinson, S.E, Maughan, P.J, Zhang, H.B, Balzotti, M.R, Kooyman, D.L, Arumuganathan, K, Bonifacio, A, Fairbanks, D.J

“…Quinoa (Chenopodium quinoa Willd.) is adapted to the harsh environments of the Andean Altiplano region. Its seeds have a well-balanced amino acid composition…”
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Osteoarthritis-like changes in the heterozygous sedc mouse associated with the HtrA1–Ddr2–Mmp-13 degradative pathway: a new model of osteoarthritis by Holt, D.W, Henderson, M.L, Stockdale, C.E, Farrell, J.T, Kooyman, D.L, Bridgewater, L.C, Seegmiller, R.E

“…Summary Objective To test the hypothesis that the spondyloepiphyseal dysplasia congenita ( sedc ) heterozygous ( sedc /+) mouse, a COL2A1 mutant, is a model…”
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MALOCCLUSION MODEL OF TEMPOROMANDIBULAR JOINT OSTEOARTHRITIS IN MICE WITH AND WITHOUT RECEPTOR FOR ADVANCED GLYCATION END PRODUCTS by Matías, E.M.Chávez, Mecham, D.K, Black, C.S, Graf, J.W, Steel, S.D, Wilhelm, S.K, Andersen, K.M, Mitchell, J.A, Macdonald, J.R, Hollis, W.R, Eggett, D.L, Reynolds, P.R, Kooyman, D.L

“…Abstract Objective This study has two aims: 1. Validate a non-invasive malocclusion model of mouse temporomandibular joint (TMJ) osteoarthritis (OA) that we…”
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Osteoarthritis in temporomandibular joint of Col2a1 mutant mice by Ricks, M.L, Farrell, J.T, Falk, D.J, Holt, D.W, Rees, M, Carr, J, Williams, T, Nichols, B.A, Bridgewater, L.C, Reynolds, P.R, Kooyman, D.L, Seegmiller, R.E

“…Abstract Objective Col2a1 gene mutations cause premature degeneration of knee articular cartilage in disproportionate micromelia ( Dmm ) and spondyloepiphesial…”
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Construction of a Llama Bacterial Artificial Chromosome Library with Approximately 9-Fold Genome Equivalent Coverage by Hinckley, J. D., Airmet, K. W., Tree, L. T., Moss, M., Blumell, S., Ulicny, K., Gustafson, A. K., Weed, M., Theodosis, R., Lehnardt, M., Genho, J., Stevens, M. R., Kooyman, D. L.

“…The Ilama is an important agricultural livestock in much of South America. The llama is increasing in popularity in the United States as a companion animal…”
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Identification and characterization of a galactosyl peptide mimetic : Implications for use in removing xenoreactive anti-A Gal antibodies by KOOYMAN, D. L, MCCLELLAN, S. B, PARKER, W, AVISSAR, P. L, VELARDO, M. A, PLATT, J. L, LOGAN, J. S

“…Gal alpha 1,3 Gal is thought to be the major antigenic epitope present on pig tissues to which XNAs bind. Removal of antibodies directed against that structure…”
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Glycosyl phosphatidylinositol anchor by Kooyman, D L, Byrne, G W, Logan, J S

“…Recently, we and others demonstrated the unique potential for glycosyl phosphatidylinositol (GPI) anchored proteins to transfer from one cell membrane to…”
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Human complement regulatory proteins protect swine-to-primate cardiac xenografts from humoral injury by McCurry, Kenneth R, Kooyman, David L, Alvarado, Cristobal G, Cotterell, Adrian H, Martin, Michael J, Logan, John S, Platt, Jeffrey L

“…The susceptibility of xenografts to hyperacute rejection is postulated to reflect in part failure of complement regulatory proteins (CRPs) to control…”
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Transgenic animals and their impact on the drug discovery industry by Dunn, DA, Pinkert, CA, Kooyman, D L

“…Transgenic animals serve as important models in translating findings in the basic sciences to potential clinical applications. Moreover, the use of transgenic…”
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Genomic analysis of genetic markers associated with inherited cardiomyopathy (round heart disease) in the turkey (Meleagris gallopavo) by Reed, K. M., Mendoza, K. M., Hu, G. R., Sullivan, L. R., Grace, M. W., Chaves, L. D., Kooyman, D. L.

“…Summary In turkeys, spontaneous cardiomyopathy or round heart (RH) disease is characterised by dilated ventricles and cardiac muscle hypertrophy. Although the…”
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A Tale of Two Joints: The Role of Matrix Metalloproteases in Cartilage Biology by Rose, Brandon J., Kooyman, D. L.

“…Matrix metalloproteinases are a class of enzymes involved in the degradation of extracellular matrix molecules. While these molecules are exceptionally…”
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Human complement regulatory proteins in transgenic animals regulate complement activation in xenoperfused organs by McCurry, K R, Kooyman, D L, Diamond, L E, Byrne, G W, Martin, M J, Logan, J S, Platt, J L

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Human complement regulatory proteins expressed in transgenic swine protect swine xenografts from humoral injury by McCurry, K R, Diamond, L E, Kooyman, D L, Byrne, G W, Martin, M J, Logan, J S, Platt, J L

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In-vitro development of zygotes from superovulated prepubertal and mature gilts by Pinkert, C A, Kooyman, D L, Baumgartner, A, Keisler, D H

“…Ten prepubertal and 8 mature gilts were superovulated with PMSG and hCG, and inseminated with fresh boar semen. Zygotes were surgically recovered from oviducts…”
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Identification and characterization of a peptide mimeotope of galactose alpha 1,3 galactose by Kooyman, D L, McClellan, S B, Parker, W R, Avissar, P L, Velardo, M A, Nielsen, D H, Platt, J L, Logan, J S

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Transgenic expression of human complement regulatory proteins in mice results in diminished complement deposition during organ xenoperfusion by McCurry, K R, Kooyman, D L, Diamond, L E, Byrne, G W, Logan, J S, Platt, J L

“…Complement activation is an essential step in the hyperacute rejection of a vascularized xenograft. Endothelial cell-associated complement regulatory proteins…”
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The role of natural anti-Gal alpha 1-3Gal antibodies in hyperacute rejection of pig-to-baboon cardiac xenotransplants by Lin, S S, Kooyman, D L, Daniels, L J, Daggett, C W, Parker, W, Lawson, J H, Hoopes, C W, Gullotto, C, Li, L, Birch, P, Davis, R D, Diamond, L E, Logan, J S, Platt, J L

“…Xenoreactive natural antibodies in humans and higher primates are directed predominantly at Gal alpha 1-3Gal. These antibodies are thought to initiate…”
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Characterization of transgenic livestock production by Pinkert, C A, Dyer, T J, Kooyman, D L, Kiehm, D J

“…The objective of transgenic livestock improvement projects is to develop and bring to market superior breeding stock, as well as germplasm for the artificial…”
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Transgenic mice expressing a chimaeric anti-E. coli immunoglobulin α heavy chain gene by KOOYMAN, D. L, PINKERT, C. A

“…To induce constitutive immunity against a pathogenic strain of Escherichia coli (K99), a rearranged immunoglobulin (Ig) heavy chain (HC) gene was constructed…”
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