Search Results - "Koone, Jordan C."

Charge Regulation in a Rieske Proton Pump Pinpoints Zero, One, and Two Proton-Coupled Electron Transfer by Koone, Jordan C., Simmang, Mikaela, Saenger, Devin L., Hunsicker-Wang, Laura M., Shaw, Bryan F.

“…The degree to which redox-driven proton pumps regulate net charge during electron transfer (ΔZET) remains undetermined due to difficulties in measuring the net…”
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A method for quantifying how the activity of an enzyme is affected by the net charge of its nearest crowded neighbor by Koone, Jordan C., Dashnaw, Chad M., Gonzalez, Mayte, Shaw, Bryan F.

“…The electrostatic effects of protein crowding have not been systematically explored. Rather, protein crowding is generally studied with co‐solvents or crowders…”
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Measuring how two proteins affect each other's net charge in a crowded environment by Dashnaw, Chad M., Koone, Jordan C., Abdolvahabi, Alireza, Shaw, Bryan F.

“…Theory predicts that the net charge (Z) of a protein can be altered by the net charge of a neighboring protein as the two approach one another below the Debye…”
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Metal migration and subunit swapping in ALS-linked SOD1: Zn2+ transfer between mutant and wild-type occurs faster than the rate of heterodimerization by Dashnaw, Chad M., Zhang, Ao Yun, Gonzalez, Mayte, Koone, Jordan C., Shaw, Bryan F.

“…The heterodimerization of WT Cu, Zn superoxide dismutase-1 (SOD1), and mutant SOD1 might be a critical step in the pathogenesis of SOD1-linked amyotrophic…”
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Complete Charge Regulation by a Redox Enzyme Upon Single Electron Transfer by Zhang, Ao Yun, Koone, Jordan C., Dashnaw, Chad M., Zahler, Collin T., Shaw, Bryan F.

“…The degree by which metalloproteins partially regulate net charge (Z) upon electron transfer (ET) was recently measured for the first time using “protein…”
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Supercharging Prions via Amyloid‐Selective Lysine Acetylation by Baumer, Katelyn M., Cook, Christopher D., Zahler, Collin T., Beard, Alexandra A., Chen, Zhijuan, Koone, Jordan C., Dashnaw, Chad M., Villacob, Raul A., Solouki, Touradj, Wood, John L., Borchelt, David R., Shaw, Bryan F.

“…Repulsive electrostatic forces between prion‐like proteins are a barrier against aggregation. In neuropharmacology, however, a prion's net charge (Z) is not a…”
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Kinetic Variability in Seeded Formation of ALS-Linked SOD1 Fibrils Across Multiple Generations by Baumer, Katelyn M, Koone, Jordan C, Shaw, Bryan F

“…The unseeded aggregation of superoxide dismutase-1 (SOD1) into amyloid-like fibrils occurs stochastically in vitro and in vivo, that is, isolated populations…”
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Oxidation of Dueling Cysteine Promotes Subunit Exchange in SOD1 by Zhang, Ao Yun, Dashnaw, Chad M., Gonzalez, Mayte, Koone, Jordan C., Wells, Nick A., Smith, Colin A., Guberman-Pfeffer, Matthew J., Shaw, Bryan F.

“…The heterodimerization of wild-type (WT) Cu, Zn superoxide dismutase-1 (SOD1) and mutant SOD1 might be a critical step in the pathogenesis of SOD1-linked…”
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Data for all: Tactile graphics that light up with picture-perfect resolution by Koone, Jordan C., Dashnaw, Chad M., Alonzo, Emily A., Iglesias, Miguel A., Patero, Kelly-Shaye, Lopez, Juan J., Zhang, Ao Yun, Zechmann, Bernd, Cook, Noah E., Minkara, Mona S., Supalo, Cary A., Wedler, Hoby B., Guberman-Pfeffer, Matthew J., Shaw, Bryan F.

“…People who are blind do not have access to graphical data and imagery produced by science. This exclusion complicates learning and data sharing between sighted…”
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Universal pictures: A lithophane codex helps teenagers with blindness visualize nanoscopic systems by Alonzo, Emily A, Lato, Travis J, Gonzalez, Mayte, Olson, Trevor L, Savage, Quentin R, Garza, Levi N, Green, Morgan T, Koone, Jordan C, Cook, Noah E, Dashnaw, Chad M, Armstrong, Darren B, Wood, John L, Garbrecht, Lisa S, Haynes, Madeline L, Jacobson, Miriam R, Guberman-Pfeffer, Matthew J, Minkara, Mona S, Wedler, Hoby B, Zechmann, Bernd, Shaw, Bryan F

“…People with blindness have limited access to the high-resolution graphical data and imagery of science. Here, a lithophane codex is reported. Its pages display…”
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Complete Charge Regulation by a Redox Enzyme Upon Single Electron Transfer by Zhang, Ao Yun, Koone, Jordan C., Dashnaw, Chad M., Zahler, Collin T., Shaw, Bryan F.

“…The degree by which metalloproteins partially regulate net charge (Z) upon electron transfer (ET) was recently measured for the first time using “protein…”
Get full text

Supercharging Prions via Amyloid‐Selective Lysine Acetylation by Baumer, Katelyn M., Cook, Christopher D., Zahler, Collin T., Beard, Alexandra A., Chen, Zhijuan, Koone, Jordan C., Dashnaw, Chad M., Villacob, Raul A., Solouki, Touradj, Wood, John L., Borchelt, David R., Shaw, Bryan F.

“…Repulsive electrostatic forces between prion‐like proteins are a barrier against aggregation. In neuropharmacology, however, a prion's net charge (Z) is not a…”
Get full text

Metal migration and subunit swapping in ALS-linked SOD1: Zn 2+ transfer between mutant and wild-type occurs faster than the rate of heterodimerization by Dashnaw, Chad M, Zhang, Ao Yun, Gonzalez, Mayte, Koone, Jordan C, Shaw, Bryan F

“…The heterodimerization of WT Cu, Zn superoxide dismutase-1 (SOD1), and mutant SOD1 might be a critical step in the pathogenesis of SOD1-linked amyotrophic…”
Get full text