Search Results - "Koo, Sung I."

Comparison of ABTS/DPPH assays to measure antioxidant capacity in popular antioxidant-rich US foods by Floegel, Anna, Kim, Dae-Ok, Chung, Sang-Jin, Koo, Sung I., Chun, Ock K.

“…To evaluate the comparability of the two most common radical scavenging assays using 2,2′-azino-bis-3-ethylbenzthiazoline-6-sulphonic acid (ABTS) and…”
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Eliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice by Gariani, Karim, Menzies, Keir J., Ryu, Dongryeol, Wegner, Casey J., Wang, Xu, Ropelle, Eduardo R., Moullan, Norman, Zhang, Hongbo, Perino, Alessia, Lemos, Vera, Kim, Bohkyung, Park, Young‐Ki, Piersigilli, Alessandra, Pham, Tho X., Yang, Yue, Ku, Chai Siah, Koo, Sung I., Fomitchova, Anna, Cantó, Carlos, Schoonjans, Kristina, Sauve, Anthony A., Lee, Ji‐Young, Auwerx, Johan

“…With no approved pharmacological treatment, nonalcoholic fatty liver disease (NAFLD) is now the most common cause of chronic liver disease in Western countries…”
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Dietary Cadmium Intake and Sources in the US by Kim, Kijoon, Melough, Melissa M, Vance, Terrence M, Noh, Hwayoung, Koo, Sung I, Chun, Ock K

“…Cadmium (Cd) is a toxic heavy metal that can contribute to numerous diseases as well as increased mortality. Diet is the primary source of Cd exposure for most…”
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Astaxanthin inhibits inflammation and fibrosis in the liver and adipose tissue of mouse models of diet-induced obesity and nonalcoholic steatohepatitis by Kim, Bohkyung, Farruggia, Callie, Ku, Chai Siah, Pham, Tho X., Yang, Yue, Bae, Minkyung, Wegner, Casey J., Farrell, Nicholas J., Harness, Ellen, Park, Young-Ki, Koo, Sung I., Lee, Ji-Young

“…The objective of this study was to determine if astaxanthin (ASTX), a xanthophyll carotenoid, can prevent obesity-associated metabolic abnormalities,…”
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Astaxanthin prevents TGFβ1-induced pro-fibrogenic gene expression by inhibiting Smad3 activation in hepatic stellate cells by Yang, Yue, Kim, Bohkyung, Park, Young-Ki, Koo, Sung I., Lee, Ji-Young

“…Non-alcoholic steatohepatitis (NASH) is a subset of non-alcoholic fatty liver disease, the most common chronic liver disease in the U.S. Fibrosis, a common…”
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Blackcurrant (Ribes nigrum) Prevents Obesity‐Induced Nonalcoholic Steatohepatitis in Mice by Lee, Yoojin, Pham, Tho X., Bae, Minkyung, Hu, Siqi, O’Neill, Edward, Chun, Ock K., Han, Myung Joo, Koo, Sung I., Park, Young‐Ki, Lee, Ji‐Young

“…Objective With increasing prevalence of nonalcoholic steatohepatitis (NASH), effective strategies to prevent NASH are needed. This study investigated whether…”
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Estimation of antioxidant intakes from diet and supplements in U.S. adults by Chun, Ock K, Floegel, Anna, Chung, Sang-Jin, Chung, Chin Eun, Song, Won O, Koo, Sung I

“…The importance of antioxidants in reducing risks of chronic diseases has been well established; however, antioxidant intakes by a free-living population have…”
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Astaxanthin prevents and reverses the activation of mouse primary hepatic stellate cells by Yang, Yue, Bae, Minkyung, Kim, Bohkyung, Park, Young-Ki, Koo, Sung I., Lee, Ji-Young

“…Activation of hepatic stellate cells (HSCs) is a critical step that leads to the development of liver fibrosis. We showed that astaxanthin (ASTX), a…”
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Dietary Total Antioxidant Capacity Is Associated with Diet and Plasma Antioxidant Status in Healthy Young Adults by Wang, Ying, Yang, Meng, PhD, Lee, Sang-Gil, MS, Davis, Catherine G., MS, RD, Koo, Sung I., PhD, Chun, Ock K., PhD, MPH

“…Abstract Dietary total antioxidant capacity (TAC), based on the cumulative antioxidant activities of all the antioxidants present in food, has been shown to be…”
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Long-Term Blackcurrant Supplementation Modified Gut Microbiome Profiles in Mice in an Age-Dependent Manner: An Exploratory Study by Cao, Lei, Lee, Sang Gil, Melough, Melissa M, Sakaki, Junichi R, Maas, Kendra R, Koo, Sung I, Chun, Ock K

“…Recent studies have suggested that blackcurrant (BC) anthocyanins have promising health benefits, possibly through regulating gut microbiome. Three- and…”
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Green tea extract attenuates hepatic steatosis by decreasing adipose lipogenesis and enhancing hepatic antioxidant defenses in ob/ob mice by Park, Hea Jin, DiNatale, Dana A, Chung, Min-Yu, Park, Young-Ki, Lee, Ji-Young, Koo, Sung I, O'Connor, Meeghan, Manautou, Jose E, Bruno, Richard S

“…Excess hepatic lipid accumulation and oxidative stress contribute to nonalcoholic fatty liver disease (NAFLD). Thus, we hypothesized that the hypolipidemic and…”
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Contribution of Anthocyanin Composition to Total Antioxidant Capacity of Berries by Lee, Sang Gil, Vance, Terrence M, Nam, Tae-Gyu, Kim, Dae-Ok, Koo, Sung I, Chun, Ock K

“…The present study aimed to evaluate the contribution of anthocyanin composition to the total antioxidant capacity (TAC) of berries having different anthocyanin…”
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Dietary Antioxidants and Prostate Cancer: A Review by Vance, Terrence M., Su, Joseph, Fontham, Elizabeth T. H., Koo, Sung I., Chun, Ock K.

“…Prostate cancer is the most common noncutaneous cancer in men in the United States. Several studies have examined the relationship between prostate cancer and…”
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Protective Effect of Detoxified Rhus verniciflua Stokes on Human Keratinocytes and Dermal Fibroblasts against Oxidative Stress and Identification of the Bioactive Phenolics by LIU, Chun-Shan, NAM, Tae-Gyu, HAN, Min-Woo, AHN, Soo-mi, CHOI, Han Seok, KIM, Tae Young, CHUN, Ock K., KOO, Sung I., KIM, Dae-Ok

“…Oxidative stress due to the over-production of reactive oxygen species (ROS) is associated with human skin aging. This study was designed to identify the…”
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Dietary green tea extract lowers plasma and hepatic triglycerides and decreases the expression of sterol regulatory element-binding protein-1c mRNA and its responsive genes in fructose-fed, ovariectomized rats by Shrestha, Sudeep, Ehlers, Sarah J, Lee, Ji-Young, Fernandez, Maria-Luz, Koo, Sung I

“…The objective of this study was to determine whether green tea (GT) inhibits the expression of genes regulating hepatic lipogenesis and intestinal lipid…”
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Blackcurrant Supplementation Improves Trabecular Bone Mass in Young but Not Aged Mice by Sakaki, Junichi, Melough, Melissa, Lee, Sang Gil, Kalinowski, Judy, Koo, Sung I, Lee, Sun-Kyeong, Chun, Ock K

“…Due to deleterious side effects of currently available medications, the search for novel, safe, and effective preventive agents for improving bone health in…”
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ATP-binding cassette transporter A1 and HDL metabolism: effects of fatty acids by Lee, Jiyoung, Park, Youngki, Koo, Sung I

“…Ample evidence indicates that dietary fatty acids alter the plasma levels of high-density lipoprotein cholesterol (HDL-C). However, the mechanisms underlying…”
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Green tea extract protects against nonalcoholic steatohepatitis in ob/ob mice by decreasing oxidative and nitrative stress responses induced by proinflammatory enzymes by Chung, Min-Yu, Park, Hea Jin, Manautou, Jose E, Koo, Sung I, Bruno, Richard S

“…Oxidative and nitrative stress responses resulting from inflammation exacerbate liver injury associated with nonalcoholic steatohepatitis (NASH) by inducing…”
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Milk sphingomyelin is more effective than egg sphingomyelin in inhibiting intestinal absorption of cholesterol and fat in rats by Noh, Sang K, Koo, Sung I

“…We reported previously that egg sphingomyelin (SM) inhibits the intestinal absorption of cholesterol and fat in rats. This study was conducted to compare the…”
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Validation of Analytical Methods for Plasma Total Antioxidant Capacity by Comparing with Urinary 8-Isoprostane Level by Lee, Sang Gil, Wang, Taoran, Vance, Terrence M, Hubert, Patrice, Kim, Dae-Ok, Koo, Sung I, Chun, Ock K

“…Although several analytical methods for measuring total antioxidant capacity (TAC) have been applied to biological samples, there were often dissimilar results…”
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