Search Results - "Koo, Jaemo"
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Clinical application of whole-genome sequencing of solid tumors for precision oncology
Published in Experimental & molecular medicine (01-08-2024)“…Genomic alterations in tumors play a pivotal role in determining their clinical trajectory and responsiveness to treatment. Targeted panel sequencing (TPS) has…”
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Target-Enhanced Whole-Genome Sequencing (TE-WGS) Shows Clinical Validity Equivalent to Commercially Available Targeted Oncology Panel
Published in Cancer research and treatment (19-09-2024)“…Cancer poses a significant global health challenge, demanding precise genomic testing for individualized treatment strategies. Targeted-panel sequencing (TPS)…”
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Abstract 2054: Whole-genome sequencing based homologous recombination deficiency testing for precision oncology of breast cancers
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Breast cancers (BCs) with defects in homologous recombination repair (HRR) pathway depend on the Poly (ADP-ribose) polymerase enzymes (PARP) for their survival…”
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Abstract 239: Whole-genome sequencing based homologous recombination deficiency testing for precision oncology of breast cancers
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Breast cancers (BCs) with defects in homologous recombination repair (HRR) pathway depend on the Poly (ADP-ribose) polymerase enzymes (PARP) for their survival…”
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Abstract 2056: Large-scale whole genome sequencing of hepatocellular carcinoma reveals stepwise cancer evolution
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Liver cancer is a leading cause of death worldwide where somatic mutation plays a key role in tumorigenesis. As such, many recent researches have been…”
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Abstract 2055: Prevalent focal amplification of oncogene in lung adenocarcinomas without canonical driver alterations
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Lung adenocarcinoma (LADC) is the most common type of lung cancer and a leading cause of death worldwide. Typical oncogenes that drive LADCs when mutated…”
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Abstract 6069: Genomic and transcriptomic characterization of medullary thyroid cancer
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Medullary thyroid carcinoma (MTC) is a rare thyroid malignancy derived from the parafollicular C cells of thyroid gland. It features relatively aggressive…”
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