Search Results - "Koo, Ada"
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5-HT containing enteroendocrine cells characterised by morphologies, patterns of hormone co-expression, and relationships with nerve fibres in the mouse gastrointestinal tract
Published in Histochemistry and cell biology (01-06-2021)“…5-HT containing enteroendocrine cells (EEC), the most abundant type of EEC in the gut, regulate many functions including motility, secretion and inflammatory…”
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Morphologies and distributions of 5-HT containing enteroendocrine cells in the mouse large intestine
Published in Cell and tissue research (01-05-2021)“…Serotonin (5-HT)-containing gastrointestinal endocrine cells contribute to regulation of numerous bodily functions, but whether these functions are related to…”
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Fat Depot–Specific Characteristics Are Retained in Strains Derived From Single Human Preadipocytes
Published in Diabetes (New York, N.Y.) (01-09-2006)“…Fat Depot–Specific Characteristics Are Retained in Strains Derived From Single Human Preadipocytes Tamara Tchkonia 1 , Nino Giorgadze 1 , Tamar Pirtskhalava 1…”
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Sites and mechanisms of action of colokinetics at dopamine, ghrelin and serotonin receptors in the rodent lumbosacral defecation centre
Published in The Journal of physiology (01-12-2023)“…Agonists of dopamine D2 receptors (D2R), 5‐hydroxytryptamine (5‐HT, serotonin) receptors (5‐HTR) and ghrelin receptors (GHSR) activate neurons in the…”
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MondoA coordinately regulates skeletal myocyte lipid homeostasis and insulin signaling
Published in The Journal of clinical investigation (01-09-2016)“…Intramuscular lipid accumulation is a common manifestation of chronic caloric excess and obesity that is strongly associated with insulin resistance. The…”
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Expression of the relaxin family peptide 4 receptor by enterochromaffin cells of the mouse large intestine
Published in Cell and tissue research (01-07-2022)“…The gastrointestinal hormone, insulin-like peptide 5 (INSL5), is found in large intestinal enteroendocrine cells (EEC). One of its functions is to stimulate…”
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Discovery of Novel Small-Molecule Inducers of Heme Oxygenase-1 That Protect Human iPSC-Derived Cardiomyocytes from Oxidative Stress
Published in The Journal of pharmacology and experimental therapeutics (01-01-2018)“…Oxidative injury to cardiomyocytes plays a critical role in cardiac pathogenesis following myocardial infarction. Transplantation of stem cell-derived…”
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A Novel Antagonist Peptide Reveals a Physiological Role of Insulin-Like Peptide 5 in Control of Colorectal Function
Published in ACS pharmacology & translational science (08-10-2021)“…Insulin-like peptide 5 (INSL5), the natural ligand for the relaxin family peptide receptor 4 (RXFP4), is a gut hormone that is exclusively produced by colonic…”
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Abundance of two human preadipocyte subtypes with distinct capacities for replication, adipogenesis, and apoptosis varies among fat depots
Published in American journal of physiology: endocrinology and metabolism (01-01-2005)“…Fat depots vary in function and size. The preadipocytes that fat cells develop from exhibit distinct regional characteristics that persist in culture. Human…”
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Identification of Inhibitors of triacylglyceride accumulation in muscle cells: comparing HTS results from 1536-well plate-based and high-content platforms
Published in Journal of biomolecular screening (01-01-2014)“…Excess caloric consumption leads to triacylglyceride (TAG) accumulation in tissues that do not typically store fat, such as skeletal muscle. This ectopic…”
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