Search Results - "Konvinse, Katherine C."

Severe Delayed Cutaneous and Systemic Reactions to Drugs: A Global Perspective on the Science and Art of Current Practice by Peter, Jonathan Grant, MD, PhD, Lehloenya, Rannakoe, MD, Dlamini, Sipho, MD, Risma, Kimberly, MD, White, Katie D., MD, PhD, Konvinse, Katherine C., BA, Phillips, Elizabeth J., MD, FIDSA, FAAAAI

“…Most immune-mediated adverse drug reactions (IM-ADRs) involve the skin, and many have additional systemic features. Severe cutaneous adverse drug reactions…”
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Multiomic single-cell sequencing defines tissue-specific responses in Stevens-Johnson syndrome and toxic epidermal necrolysis by Gibson, Andrew, Ram, Ramesh, Gangula, Rama, Li, Yueran, Mukherjee, Eric, Palubinsky, Amy M., Campbell, Chelsea N., Thorne, Michael, Konvinse, Katherine C., Choshi, Phuti, Deshpande, Pooja, Pedretti, Sarah, Fear, Mark W., Wood, Fiona M., O’Neil, Richard T., Wanjalla, Celestine N., Kalams, Spyros A., Gaudieri, Silvana, Lehloenya, Rannakoe J., Bailin, Samuel S., Chopra, Abha, Trubiano, Jason A., Peter, Jonny G., Mallal, Simon A., Phillips, Elizabeth J.

“…Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) is a rare but life-threatening cutaneous drug reaction mediated by human leukocyte antigen…”
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HLA-A32:01 is strongly associated with vancomycin-induced drug reaction with eosinophilia and systemic symptoms by Konvinse, Katherine C., Trubiano, Jason A., Pavlos, Rebecca, James, Ian, Shaffer, Christian M., Bejan, Cosmin A., Schutte, Ryan J., Ostrov, David A., Pilkinton, Mark A., Rosenbach, Misha, Zwerner, Jeffrey P., Williams, Kristina B., Bourke, Jack, Martinez, Patricia, Rwandamuriye, Francois, Chopra, Abha, Watson, Mark, Redwood, Alec J., White, Katie D., Mallal, Simon A., Phillips, Elizabeth J.

“…Vancomycin is a prevalent cause of the severe hypersensitivity syndrome drug reaction with eosinophilia and systemic symptoms (DRESS), which leads to…”
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Cross-reactivity between vancomycin, teicoplanin, and telavancin in patients with HLA-A∗32:01–positive vancomycin-induced DRESS sharing an HLA class II haplotype by Nakkam, Nontaya, Gibson, Andrew, Mouhtouris, Effie, Konvinse, Katherine C., Holmes, Natasha E., Chua, Kyra Y., Deshpande, Pooja, Li, Danmeng, Ostrov, David A., Trubiano, Jason, Phillips, Elizabeth J.

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Human Herpesvirus 6 Detection during the Evaluation of Sepsis in Infants Using the FilmArray Meningitis/Encephalitis Panel by Dantuluri, Keerti L., Konvinse, Katherine C., Crook, Jennifer, Thomsen, Isaac P., Banerjee, Ritu

“…We used the FilmArray meningitis/encephalitis panel for evaluation of sepsis in febrile neonates. We detected human herpesvirus 6, a virus we did not routinely…”
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Applications of Immunopharmacogenomics: Predicting, Preventing, and Understanding Immune-Mediated Adverse Drug Reactions by Karnes, Jason H, Miller, Matthew A, White, Katie D, Konvinse, Katherine C, Pavlos, Rebecca K, Redwood, Alec J, Peter, Jonathan G, Lehloenya, Rannakoe, Mallal, Simon A, Phillips, Elizabeth J

“…Adverse drug reactions (ADRs) are a significant health care burden. Immune-mediated adverse drug reactions (IM-ADRs) are responsible for one-fifth of ADRs but…”
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Multi-omics analysis of mucosal and systemic immunity to SARS-CoV-2 after birth by Wimmers, Florian, Burrell, Allison R., Feng, Yupeng, Zheng, Hong, Arunachalam, Prabhu S., Hu, Mengyun, Spranger, Sara, Nyhoff, Lindsay E., Joshi, Devyani, Trisal, Meera, Awasthi, Mayanka, Bellusci, Lorenza, Ashraf, Usama, Kowli, Sangeeta, Konvinse, Katherine C., Yang, Emily, Blanco, Michael, Pellegrini, Kathryn, Tharp, Gregory, Hagan, Thomas, Chinthrajah, R. Sharon, Nguyen, Tran T., Grifoni, Alba, Sette, Alessandro, Nadeau, Kari C., Haslam, David B., Bosinger, Steven E., Wrammert, Jens, Maecker, Holden T., Utz, Paul J., Wang, Taia T., Khurana, Surender, Khatri, Purvesh, Staat, Mary A., Pulendran, Bali

“…The dynamics of immunity to infection in infants remain obscure. Here, we used a multi-omics approach to perform a longitudinal analysis of immunity to severe…”
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The Combined Utility of Ex Vivo IFN-γ Release Enzyme-Linked ImmunoSpot Assay and In Vivo Skin Testing in Patients with Antibiotic-Associated Severe Cutaneous Adverse Reactions by Trubiano, Jason A., Strautins, Kaija, Redwood, Alec J., Pavlos, Rebecca, Konvinse, Katherine C., Aung, Ar Kar, Slavin, Monica A., Thursky, Karin A., Grayson, M. Lindsay, Phillips, Elizabeth J.

“…For severe cutaneous adverse reactions (SCARs) associated with multiple antibiotics dosed concurrently, clinical causality is challenging and diagnostic…”
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A Rapid Allele-Specific Assay for HLA-A32:01 to Identify Patients at Risk for Vancomycin-Induced Drug Reaction with Eosinophilia and Systemic Symptoms by Rwandamuriye, Francois X., Chopra, Abha, Konvinse, Katherine C., Choo, Linda, Trubiano, Jason A., Shaffer, Christian M., Watson, Mark, Mallal, Simon A., Phillips, Elizabeth J.

“…Human leukocyte antigen (HLA) alleles have been implicated as risk factors for immune-mediated adverse drug reactions. The authors recently reported a strong…”
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Old dog begging for new tricks: current practices and future directions in the diagnosis of delayed antimicrobial hypersensitivity by Konvinse, Katherine C, Phillips, Elizabeth J, White, Katie D, Trubiano, Jason A

“…PURPOSE OF REVIEWAntimicrobials are a leading cause of severe T cell-mediated adverse drug reactions (ADRs). The purpose of this review is to address the…”
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Altered TGF‐α/β signaling drives cooperation between breast cancer cell populations by Franco, Omar E., Tyson, Darren R., Konvinse, Katherine C., Udyavar, Akshata R., Estrada, Lourdes, Quaranta, Vito, Crawford, Susan E., Hayward, Simon W.

“…ABSTRACT The role of tumor heterogeneity in regulating disease progression is poorly understood. We hypothesized that interactions between subpopulations of…”
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Single Cell Approaches to Define the Pathogenic Immune Cells that Mediate Drug Hypersensitivity by White, Katie D., Konvinse, Katherine C., Pilkinton, Mark A., Redwood, Alec, Trubiano, Jason A., Peter, Jonathan Grant, Lehloenya, Rannakoe, Chung, Wen-Hung, Hung, Shuen-Iu, Pan, Ren-You, Chopra, Abha, Barnett, Louise, Gangula, Rama, Mallal, Simon A., Phillips, Elizabeth J.

“…Methods Single cell technologies including T-cell receptor αβ sequencing, multi-parameter flow cytometry, full transcriptome RNA-seq, and mass cytometry were…”
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The Combined Utility of Ex vivo IFN-g Release Enzyme-Linked ImmunoSpot Assay and In vivo Skin Testing in Patients With Antibiotic-Associated Severe Cutaneous Adverse Reactions by Trubiano, Jason A., Strautins, Kaija, Redwood, Alec J., Pavlos, Rebecca, Konvinse, Katherine C., Aung, Ar Kar, Slavin, Monica A., Thursky, Karin A., Grayson, M. Lindsay, Phillips, Elizabeth J.

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Human Herpesvirus 6 Detection during the Evaluation of Sepsis in Infants Using the FilmArray Meningitis/Encephalitis Panel by Dantuluri, Keerti L, Konvinse, Katherine C, Crook, Jennifer, Thomsen, Isaac P, Banerjee, Ritu

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