Search Results - "Konrad, F."
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Implications for post critical illness trial design: sub-phenotyping trajectories of functional recovery among sepsis survivors
Published in Critical care (London, England) (25-09-2020)“…Background Patients who survive critical illness suffer from a significant physical disability. The impact of rehabilitation strategies on health-related…”
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Quantifying epigenetic modulation of nucleosome breathing by high-throughput AFM imaging
Published in Biophysical journal (01-03-2022)“…Nucleosomes are the basic units of chromatin and critical for storage and expression of eukaryotic genomes. Chromatin accessibility and gene readout are…”
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The decisive role of acidophilic bacteria in concrete sewer networks: A new model for fast progressing microbial concrete corrosion
Published in Cement and concrete research (01-11-2017)“…This study introduces a novel approach intertwining analytics of spatial microbial distribution with chemical, mineralogical and (micro)structural related…”
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Addressing the post-acute sequelae of SARS-CoV-2 infection: a multidisciplinary model of care
Published in The lancet respiratory medicine (01-11-2021)“…As of July 31, 2021, SARS-CoV-2 had infected almost 200 million people worldwide. The growing burden of survivorship is substantial in terms of the complexity…”
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Barium partitioning in calcite and aragonite as a function of growth rate
Published in Geochimica et cosmochimica acta (15-09-2018)“…Calcite and aragonite growth rate experiments have been performed in the presence of aqueous Ba at 25 °C using the constant addition technique as a function of…”
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MET amplification status in therapy-naïve adeno- and squamous cell carcinomas of the lung
Published in Clinical cancer research (15-02-2015)“…MET is a potential therapeutic target in lung cancer and both MET tyrosine kinase inhibitors and monoclonal antibodies have entered clinical trials. MET…”
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Trajectories of post-traumatic stress in sepsis survivors two years after ICU discharge: a secondary analysis of a randomized controlled trial
Published in Critical care (London, England) (29-01-2024)“…Post-traumatic stress has been identified as a frequent long-term complication in survivors of critical illnesses after sepsis. Little is known about long-term…”
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Development of subtype-selective oestrogen receptor-based therapeutics
Published in Nature reviews. Drug discovery (01-10-2011)“…Key Points The biological effects of natural and synthetic oestrogen-like ligands are mediated by two oestrogen receptor (ER) subtypes, ERα and ERβ. ERα and…”
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Trajectories of depression in sepsis survivors: an observational cohort study
Published in Critical care (London, England) (29-04-2021)“…Advances in critical care medicine have led to a growing number of critical illness survivors. A considerable part of them suffers from long-term sequelae,…”
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CXCR2 in Acute Lung Injury
Published in Mediators of Inflammation (01-01-2012)“…In pulmonary inflammation, recruitment of circulating polymorphonuclear leukocytes is essential for host defense and initiates the following specific immune…”
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Free Energy Landscape and Dynamics of Supercoiled DNA by High-Speed Atomic Force Microscopy
Published in ACS nano (26-12-2018)“…DNA supercoiling fundamentally constrains and regulates the storage and use of genetic information. While the equilibrium properties of supercoiled DNA are…”
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The rostro-caudal gradient in the prefrontal cortex and its modulation by subthalamic deep brain stimulation in Parkinson’s disease
Published in Scientific reports (22-01-2021)“…Deep brain stimulation of the subthalamic nucleus (STN-DBS) alleviates motor symptoms in Parkinson’s disease (PD) but also affects the prefrontal cortex (PFC),…”
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13
Usability of a mHealth Solution using Speech Recognition for Point-of-care Diagnostic Management
Published in Journal of medical systems (02-02-2023)“…The administrative burden for physicians in the hospital can affect the quality of patient care. The Service Center Medical Informatics (SMI) of the University…”
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Randomized controlled study of early medication change for non-improvers to antidepressant therapy in major depression – The EMC trial
Published in European neuropsychopharmacology (01-04-2016)“…Abstract Patients with Major Depressive Disorder (MDD) and no improvement after two weeks of antidepressant pharmacotherapy have a high risk of treatment…”
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Tissue heme oxygenase-1 exerts anti-inflammatory effects on LPS-induced pulmonary inflammation
Published in Mucosal immunology (2016)“…Heme oxygenase-1 (HO-1) has been shown to display anti-inflammatory properties in models of acute pulmonary inflammation. For the first time, we investigated…”
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Definition of a fluorescence in-situ hybridization score identifies high- and low-level FGFR1 amplification types in squamous cell lung cancer
Published in Modern pathology (01-11-2012)“…We recently reported fibroblast growth factor receptor-type 1 ( FGFR1 ) amplification to be associated with therapeutically tractable FGFR1 dependency in…”
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Only I Know Now, of Course, How to Deal With it, or Better to Deal With it: A Mixed Methods Phase II Study of a Cognitive and Behavioral Intervention for the Management of Episodic Breathlessness
Published in Journal of pain and symptom management (01-05-2022)“…Episodic breathlessness is characterized by increased breathlessness intensity, and it is burdensome for patients. A vicious cycle of…”
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Test-Retest Reliability of the Tower of London Planning Task (TOL-F)
Published in Psychological assessment (01-09-2015)“…Test-retest reliability is difficult to establish for measures of executive functioning that rely on task novelty. Correspondingly, evidence on the test-retest…”
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The impact of physiological noise on hemodynamic-derived estimates of directed functional connectivity
Published in Brain Structure and Function (01-12-2019)“…Measuring the strength of directed functional interactions between brain regions is fundamental to understand neural networks. Functional near-infrared…”
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The Amount of Mitochondrial DNA in Blood Reflects the Course of a Depressive Episode
Published in Biological psychiatry (1969) (15-09-2016)Get full text
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