Search Results - "Konopka, Elizabeth"

A recombinant technique for mapping functional sites of heterotrimeric collagen helices: Collagen IV CB3 fragment as a prototype for integrin binding by Boudko, Sergei P., Konopka, Elizabeth H., Kim, Woojin, Taga, Yuki, Mizuno, Kazunori, Springer, Timothy A., Hudson, Billy G., Moy, Terence I., Lin, Fu-Yang

“…Collagen superfamily of proteins is a major component of the extracellular matrix. Defects in collagens underlie the cause of nearly 40 human genetic diseases…”
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The Discovery of MORF-627, a Highly Selective Conformationally-Biased Zwitterionic Integrin αvβ6 Inhibitor for Fibrosis by Harrison, Bryce A., Dowling, James E., Bursavich, Matthew G., Troast, Dawn M., Chong, Katherine M., Hahn, Kristopher N., Zhong, Cheng, Mulvihill, Kristen M., Nguyen, Hanh, Monroy, Meghan F., Qiao, Qi, Sosa, Brian, Mostafavi, Siavash, Smukste, Inese, Lee, Dooyoung, Cappellucci, Laura, Konopka, Elizabeth H., Nowakowski, Patrycja, Stawski, Lukasz, Senices, Mayra, Nguyen, Minh Hai, Kapoor, Parmita S., Luus, Lia, Sullivan, Andrew, Bortolato, Andrea, Svensson, Mats, Hickey, Eugene R., Konze, Kyle D., Day, Tyler, Kim, Byungchan, Negri, Ana, Gerasyuto, Aleksey I., Moy, Terence I., Lu, Min, Ray, Adrian S., Wang, Liangsu, Cui, Dan, Lin, Fu-Yang, Lippa, Blaise, Rogers, Bruce N.

“…Inhibition of integrin αvβ6 is a promising approach to the treatment of fibrotic disease such as idiopathic pulmonary fibrosis. Screening a small library…”
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595 Inhibition of integrin αvβ8 in combination with low dose radiation induces antitumor effect in advanced immune checkpoint blockade refractory tumor model by Reszka-Blanco, Natalia, Krumpoch, Megan, Mentzer, Michaela, Yadav, Vinod Yadav, Bannister, Brianna, Cui, Dan, Konopka, Elizabeth, Lee, Dooyoung, Lin, Fu-Yang, Moy, Terence, Nebelitsky, Eugene, Qiao, Qi, Smutske, Inese, Root, Charlotte, Allison, Patrick, Krueger, Sarah, Troast, Dawn, Lippa, Blaise, Rogers, Bruce, Ray, Adrian

“…BackgroundIntegrin αvβ8 activates TGFβ in immune cells. αvβ8 inhibitors have been shown to potentiate immune checkpoint blockade (ICB) in preclinical models…”
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Abstract 4139371: Treatment of pulmonary arterial hypertension by blocking integrin a5b1, a potential disease-modifying strategy by Montesinos, Monica, Lemay, Sarah-Eve, Kapoor, Parmita, Rapisardi, Hailey, Nguyen, Minh Hai, Kim, Haejin, Akram, Muzaffar, Jain, Dhawal, Konopka, Elizabeth, Moy, Terence I., Smukste, Inese, McTeague, T. Andrew, Dowling, James, Lama, Sujan, Pondish, Jessica, Qiao, Qi, Monroy, Meghan Monroy, Lin, Albert, Wang, Hua, Boucherat, Olivier, Sauvaget, Melanie, Potus, Francois, Breuils Bonnet, Sandra, Theberge, Charlie, Provencher, Steeve, Ray, Adrian, Lippa, Blaise, Bonnet, Sebastien, Goodwin, Bryan, Lu, Min

“…Abstract only Introduction: Pulmonary arterial hypertension (PAH) is marked by pathological remodeling of distal arteries, driven by hyperplasia of pulmonary…”
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