Search Results - "Konopka, Christian J."
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Intratumoral generation of photothermal gold nanoparticles through a vectorized biomineralization of ionic gold
Published in Nature communications (10-09-2020)“…Various cancer cells have been demonstrated to have the capacity to form plasmonic gold nanoparticles when chloroauric acid is introduced to their cellular…”
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In Vitro and In Vivo Imaging-Based Evaluation of Doxorubicin Anticancer Treatment in Combination with the Herbal Medicine Black Cohosh
Published in International journal of molecular sciences (15-12-2023)“…As a substitution for hormone replacement therapy, many breast cancer patients use black cohosh (BC) extracts in combination with doxorubicin (DOX)-based…”
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Molecularly targeted nanoparticles: an emerging tool for evaluation of expression of the receptor for advanced glycation end products in a murine model of peripheral artery disease
Published in Cellular & molecular biology letters (16-03-2021)“…Molecular imaging with molecularly targeted probes is a powerful tool for studying the spatio-temporal interactions between complex biological processes. The…”
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Nanocarriers targeting adipose macrophages increase glucocorticoid anti-inflammatory potency to ameliorate metabolic dysfunction
Published in Biomaterials science (21-01-2021)“…Obesity is associated with systemic inflammation due to macrophage accumulation in adipose tissue (AT). AT macrophages are, therefore, a target for…”
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Impact of administration route on nanocarrier biodistribution in a murine colitis model
Published in Journal of experimental nanoscience (2022)“…The incidence of inflammatory bowel disease (IBD) is increasing worldwide. Although current diagnostic and disease monitoring tests for IBD sensitively detect…”
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Multimodal Nanocarrier Probes Reveal Superior Biodistribution Quantification by Isotopic Analysis over Fluorescence
Published in ACS nano (28-01-2020)“…Absolute measurements of biodistribution are essential for understanding and optimizing the function of nanomaterials for in vivo diagnostic and therapeutic…”
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Dextran-Mimetic Quantum Dots for Multimodal Macrophage Imaging In Vivo, Ex Vivo, and In Situ
Published in ACS nano (22-02-2022)“…Macrophages are white blood cells with diverse functions contributing to a healthy immune response as well as the pathogenesis of cancer, osteoarthritis,…”
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Objective Assessments in Diagnoses and Treatment: A Proposed Change in Paradigm
Published in Clinical EEG and neuroscience (01-04-2021)“…For patients with psychiatric disorders, current diagnostic and treatment approaches are far from optimal. The clinical interview drives the standard…”
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Quantitative imaging of the receptor for advanced glycation end-products in prostate cancer
Published in European journal of nuclear medicine and molecular imaging (01-10-2020)“…Purpose Current screening and monitoring of prostate cancer (PCa) is insufficient, producing inaccurate diagnoses. Presence of the receptor for advanced…”
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Multimodal imaging of the receptor for advanced glycation end-products with molecularly targeted nanoparticles
Published in Theranostics (01-01-2018)“…The receptor for advanced glycation end-products (RAGE) is central to multiple disease states, including diabetes-related conditions such as peripheral…”
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Evaluation of a dimeric-cRGD peptide for targeted PET-CT imaging of peripheral angiogenesis in diabetic mice
Published in Scientific reports (29-03-2018)“…The α V β 3 integrin plays an important role in many physiological functions and pathological disorders. α V β 3 is minimally expressed in normal quiescent…”
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Multimodal Assessment of Mesenchymal Stem Cell Therapy for Diabetic Vascular Complications
Published in Theranostics (01-01-2017)“…Peripheral arterial disease (PAD) is a debilitating complication of diabetes mellitus (DM) that leads to thousands of injuries, amputations, and deaths each…”
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