Search Results - "Konokhova, Yana"

Variation in muscle and neuromuscular junction morphology between atrophy-resistant and atrophy-prone muscles supports failed re-innervation in aging muscle atrophy by Skinner, Sarah K., Fenton, Andrew I., Konokhova, Yana, Hepple, Russell T.

“…In advanced age, there is an accelerated decline in skeletal muscle mass that appears to be secondary to repeated cycles of denervation-reinnervation and…”
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Mitochondrial DNA Mutations Induce Neuromuscular Junction Degeneration by Anagnostou, Maria‐Eleni, Burke, Sarah S., Konokhova, Yana, Ferguson, Cole, Fenton, Andrew, Kim, Mi‐Jung, Someya, Shinichi, Hepple, Russell T.

“…Introduction Mitochondrial dysfunction is frequently posited as a cause of aging muscle atrophy. One of the proposed mechanisms involves an age‐related…”
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Anthracycline-containing chemotherapy causes long-term impairment of mitochondrial respiration and increased reactive oxygen species release in skeletal muscle by Gouspillou, Gilles, Scheede-Bergdahl, Celena, Spendiff, Sally, Vuda, Madhusudanarao, Meehan, Brian, Mlynarski, Heather, Archer-Lahlou, Elodie, Sgarioto, Nicolas, Purves-Smith, Fennigje M., Konokhova, Yana, Rak, Janusz, Chevalier, Stéphanie, Taivassalo, Tanja, Hepple, Russell T., Jagoe, R. Thomas

“…Anticancer treatments for childhood acute lymphoblastic leukaemia (ALL) are highly effective but are now implicated in causing impaired muscle function in…”
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Reduction in single muscle fiber rate of force development with aging is not attenuated in world class older masters athletes by Power, Geoffrey A, Minozzo, Fábio C, Spendiff, Sally, Filion, Marie-Eve, Konokhova, Yana, Purves-Smith, Maddy F, Pion, Charlotte, Aubertin-Leheudre, Mylène, Morais, José A, Herzog, Walter, Hepple, Russell T, Taivassalo, Tanja, Rassier, Dilson E

“…Normal adult aging is associated with impaired muscle contractile function; however, to what extent cross-bridge kinetics are altered in aging muscle is not…”
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Eccentric Ergometer Training Promotes Locomotor Muscle Strength but Not Mitochondrial Adaptation in Patients with Severe Chronic Obstructive Pulmonary Disease by MacMillan, Norah J, Kapchinsky, Sophia, Konokhova, Yana, Gouspillou, Gilles, de Sousa Sena, Riany, Jagoe, R Thomas, Baril, Jacinthe, Carver, Tamara E, Andersen, Ross E, Richard, Ruddy, Perrault, Hélène, Bourbeau, Jean, Hepple, Russell T, Taivassalo, Tanja

“…Eccentric ergometer training (EET) is increasingly being proposed as a therapeutic strategy to improve skeletal muscle strength in various cardiorespiratory…”
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Mitochondrial Involvement and Plasticity in Muscle Aging and Age-Related Disease by Konokhova, Yana

“…English: Skeletal muscle adaptability and plasticity are highly dependent on mitochondrial function. Mitochondria regulate critical intracellular functions,…”
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Cross-bridge Kinetics Impairment In Elite Octogenarian Masters Athletes: 3243 Board #4 May 30, 8: 00 AM - 9: 30 AM by Minozzo, Fábio C., Power, Geoffrey A., Filion, Marie-Eve, Konokhova, Yana, Morais, José A., Aubertln-Leheudre, Mylène, Pion, Charlotte, Hepple, Russell T., Rassier, Dilson E., Taivassalo, Tanja

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Failed upregulation of TFAM protein and mitochondrial DNA in oxidatively deficient fibers of chronic obstructive pulmonary disease locomotor muscle by Konokhova, Yana, Spendiff, Sally, Jagoe, R Thomas, Aare, Sudhakar, Kapchinsky, Sophia, MacMillan, Norah J, Rozakis, Paul, Picard, Martin, Aubertin-Leheudre, Mylène, Pion, Charlotte H, Bourbeau, Jean, Hepple, Russell T, Taivassalo, Tanja

“…Low mitochondrial content and oxidative capacity are well-established features of locomotor muscle dysfunction, a prevalent and debilitating systemic…”
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Prevalence of Mitochondrial Respiratory Chain Deficiency in Skeletal Muscle of Chronic Obstructive Pulmonary Disease Patients by Konokhova, Yana, Picard, Martin, Gouspillou, Gilles, Kapchinsky, Sophia, Baril, Jacinthe, Jagoe, Thomas, Taivassalo, Tanja

“…To quantify the levels of COX deficient myofibers in patients with COPD. Histochemistry using combined COX and succinate dehydrogenase (SDH, a respiratory…”
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